蛋白

硫氧还蛋白1人类, 重组, 大肠杆菌

MBS203108

0.1毫克

255美元

重组蛋白

硫氧还蛋白1人类, 重组, 大肠杆菌

硫氧还蛋白1

TRX1; TRX2; Thioredoxin-1; Thioredoxin I; TR-I; Thioredoxin-2; Thioredoxin-1; ADF; Surface associated sulphydryl protein; TXN protein; ATL derived factor; DKFZp686B1993; MGC61975; SASP; Thioredoxin; TRDX; TRX; TRX 1; TXN

thioredoxin isoform 1; Thioredoxin; thioredoxin; ADF; ATL-derived factor; SASP; TXN delta 3; surface-associated sulphydryl protein; thioredoxin delta 3; thioredoxin; ATL-derived factor; ADF; Surface-associated sulphydryl protein; SASP

TXN; TXN; TRX; TRDX; TRX1; TRDX; TRX; TRX1; Trx; ADF; SASP

THIO_HUMAN

105

MVKQIESKTA FQEALDAAGD KLVVVDFSAT WCGPCKMIKP FFHSLSEKYS NVIFLEVDVD DCQDVASECE VKCMPTFQFF KKGQKVGEFS GANKEKLEAT INELV

> 95% by SDS - PAGE

液体。 在磷酸盐缓冲液(PBS), pH值7.4

1毫克/毫升(由布拉德福德Bradford检测确定)

Can be stored at 4 degree C short term (1-2 weeks). For long term storage, aliquot and store at -20 degree C or -70 degree C. Avoid repeated freezing and thawing cycles.

十二烷基磺酸钠-PAGE

Antigen Species: Human

Expression System: E Coli. Bioactivity: Specific activity is 7-10 A650/min/mg, obtained by measuring the increase of insulin precipitation in absorbance at 650 nm resulting from the reduction of insulin. Please refer to our activity assay protocol. Assay: 1. Prepare a 1ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris, 63mM sodium phosphate, 1mM DTT, 0.1% (w/v) insulin, 2mM EDTA. 2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately. 3. Incubate at 25C for 20 minutes. 4. Record the increase in A650nm for 15 minutes

Redox Proteins

Thioredoxin(Trx) is a low molecular weight redox protein. Trx contains a redox active disulfide/dithiol group within the conserved Cys-Gly-Pro-Cys active site. It is involved in the first unique step in DNA synthesis. Trx also provides control over a number of transcription factors affecting cell proliferation and death through a mechanism referred to as redox regulation. Recombinant human thioredoxin-1 was overexpressed in E. coli and purified by using conventional chromatography techniques

Pigiet VP., et al.(1986) Proc. Natl.Acad.Sci. uSA 83(20):7643-7. Lundstrom J., et al. (1990) J.Biol.Chem. 265(16):9114-20. Laurent TC., et al. (1964) J Biol Chem. 239:3436-44.

50592994

NP_003320

NM_003329.3

11.7 kDa (105 aa), confirmed by MALDI-TOF.

Cellular Senescence Pathway 905991!!Cellular Responses To Stress Pathway 645258!!Detoxification Of Reactive Oxygen Species Pathway 1127552!!Folic Acid Network Pathway 920880!!Folic Acid Network Pathway 219799!!Folic Acid Network Pathway 198383!!Immune System Pathway 106386!!Inflammasomes Pathway 366166!!Innate Immune System Pathway 106387!!Metabolism Pathway 477135

The protein encoded by this gene acts as a homodimer and is involved in many redox reactions. The encoded protein is active in the reversible S-nitrosylation of cysteines in certain proteins, which is part of the response to intracellular nitric oxide. This protein is found in the cytoplasm. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]

0.1毫克

255美元