蛋白

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)

MBS2011305

0.01毫克

185美元

重组蛋白

Recombinant A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)

A Disintegrin And Metalloproteinase With Thrombospondin 8 (ADAMTS8)

A disintegrin and metalloproteinase with thrombospondin motifs 8 preproprotein; A disintegrin and metalloproteinase with thrombospondin motifs 8; A disintegrin and metalloproteinase with thrombospondin motifs 8; METH-2; METH-8; ADAMTS-8; ADAM-TS 8; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 8; ADAM metallopeptidase with thrombospondin type 1 motif, 8; METH-2; METH-8

ADAMTS8

ADAMTS8;ADAMTS8;METH2;ADAM-TS8;METH2;ADAM-TS 8;ADAM-TS8;ADAMTS-8

ATS8_HUMAN

大肠杆菌

人类

> 95%

PBS, pH7.4, containing 1mM DTT, 5% trehalose, 0.01% sarcosyl and Proclin300.

200微克/毫升

Storage : Avoid repeated freeze/thaw cycles.Store at 2-8 degree C for one month.Aliquot and store at -80 degree C for 12 months. Stability Test : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed.The loss rate is less than 5% within the expiration date under appropriate storage condition

SDS-PAGE; WB; ELISA; IP; CoIP; Purification; Amine Reactive Labeling. (May be suitable for use in other assays to be determined by the end user.)

Source: Prokaryotic expression. Residues: Leu832~Leu889. Tags: N-terminal His-Tag. Tissue Specificity: Lung. Subcellular Location: Secreted, extracellular space, extracellular matrix. Traits: Freeze-dried powder

Predicted isoelectric point: 6.3. Predicted Molecular Mass: 7.6kDa. Accurate Molecular Mass: 13kDa as determined by SDS-PAGE reducing conditions. Usage: Reconstitute in PBS (pH7.4) to a concentration of 0.1-1.0 mg/mL. Do not vortex

153792351

NP_008968.4

NM_007037.4

Q9UP79

Degradation Of The Extracellular Matrix Pathway (576263); Degradation Of The Extracellular Matrix Pathway (934113); Extracellular Matrix Organization Pathway (576262); Extracellular Matrix Organization Pathway (934100)

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. [provided by RefSeq, Jul 2008]

ADAMTS8: Has anti-angiogenic properties. Protein type: EC 3.4.24.-; Motility/polarity/chemotaxis; Secreted; Protease; Secreted, signal peptide; Cell cycle regulation. Chromosomal Location of Human Ortholog: 11q25. Cellular Component: extracellular matrix; proteinaceous extracellular matrix. Molecular Function: heparin binding; integrin binding; metallopeptidase activity; zinc ion binding; metalloendopeptidase activity; low affinity phosphate transmembrane transporter activity. Biological Process: negative regulation of cell proliferation; proteolysis

0.01毫克

185美元

0.05毫克

380

0.1毫克

585