抗体

多克隆抗体血小板/内皮细胞 粘连分子(PECAM1)

MBS2005476

0.01毫克

110美元

多克隆

兔

未共轭

免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀

抗体

多克隆抗体血小板/内皮细胞 粘连分子(PECAM1)

[血小板/内皮细胞 粘连分子(PECAM1)]

[血小板内皮细胞 粘连分子;血小板内皮细胞 粘连分子;血小板内皮细胞 粘连分子;血小板和内皮细胞 粘连分子1;CD_antigen:CD31]

[PECAM1]

[Pecam1; Pecam1; CD31; Pecam; Pecam; PECAM-1]

多克隆

IgG

兔

大鼠

The antibody is a Rabbit polyclonal antibody raised against PECAM1. It has been selected for its ability to recognize PECAM1 in immunohistochemical staining and western blotting.

Antigen-specific Affinity Chromatography

Supplied as solution form in 0.01M PBS, pH7.4, containing 0.05% Proclin-300, 50% glycerol

200微克/毫升

Storage: Avoid repeated freeze/thaw cycles. Store at 4 degree C for frequent use. Aliquot and store at -20 degree C for 12 months. Stability Test: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 degree C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.

免疫印迹;免疫组化;免疫细胞化学;免疫沉淀

Western blotting: 0.5-5µg/mL. Immunocytochemistry in formalin fixed cells: 5-20µg/mL. Immunohistochemistry in formalin fixed frozen section: 5-20µg/mL. Immunohistochemistry in paraffin section: 5-20µg/mL. Optimal working dilutions must be determined by end user

免疫印迹(免疫印迹)

免疫组化(免疫组化)

Source: Polyclonal antibody preparation. Traits: Liquid. Immunogen: Recombinant PECAM1 (Arg459~Glu624) expressed in E.coli.

Conjugated Antibody: The APC conjugated antibody version of this item is also available as catalog #MBS2041390

75832033

NP_113779.1

NM_031591.1

Q3SWT0

76,189 Da

Cell Adhesion Molecules (CAMs) Pathway (83461); Cell Adhesion Molecules (CAMs) Pathway (480); Leukocyte Transendothelial Migration Pathway (83475); Leukocyte Transendothelial Migration Pathway (494); Malaria Pathway (152662); Malaria Pathway (152657)

cell adhesion molecule, also intracellular signaling molecule; may mediate leukocyte adhesion and migration, angiogenesis, and thrombosis [RGD, Feb 2006]

PECAM-1: a cell adhesion molecule expressed on platelets and at endothelial cell intercellular junctions. Plays a role in modulation of integrin-mediated cell adhesion, transendothelial migration, angiogenesis, apoptosis, cell migration, negative regulation of immune cell signaling, autoimmunity, macrophage phagocytosis, IgE-mediated anaphylaxis and thrombosis. Undergoes alternative splicing, generating multiple isoforms in vascular beds of various tissues. Protein type: Cell adhesion; Cell development/differentiation; Membrane protein, integral; Motility/polarity/chemotaxis. Chromosomal Location of Human Ortholog: 10q32.1. Cellular Component: cell junction; cell surface; external side of plasma membrane; extracellular space; integral component of membrane; membrane; membrane raft; plasma membrane; ruffle; smooth muscle contractile fiber. Molecular Function: protein phosphatase binding. Biological Process: angiogenesis; cell adhesion; diapedesis; endothelial cell migration; endothelial cell morphogenesis; negative regulation of actin filament polymerization; negative regulation of peptidyl-tyrosine phosphorylation; phagocytosis; positive regulation of cellular extravasation; positive regulation of leukocyte migration; positive regulation of tyrosine phosphorylation of STAT protein; regulation of cell migration; Rho protein signal transduction; wound healing

0.01毫克

110美元

0.02毫克

125

0.05毫克

175

0.1毫克

225

0.2毫克

330

1毫克

785