抗体

兔抗人类水通道蛋白4多克隆抗体(AQP4)

MBS1491961

0.05毫升

120美元

多克隆

兔

未共轭

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 酶免疫法

抗体

兔抗人类水通道蛋白4多克隆抗体(AQP4)

[水通道蛋白4]

[Aquaporin-4 (AQP-4) (Mercurial-insensitive water channel) (MIWC) (WCH4),AQP4]

[aquaporin-4 isoform M1; Aquaporin-4; aquaporin-4; aquaporin 4; Mercurial-insensitive water channel; MIWC; WCH4]

[AQP4]

[AQP4;AQP4;MIWC;WCH4;AQP-4;MIWC]

AQP4_HUMAN

多克隆

IgG

兔

人类, 小鼠

323

抗原亲和纯化

Liquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

Recommended dilution: WB:1:500-2000

免疫印迹(免疫印迹)

Conjugate: Non-conjugated. Species: Human. Research Area: Signal Transduction. Target Names: AQP4

Immunogen: Recombinant human Aquaporin-4 protein (244-323aa). Santa Cruz Alternative: Potential replacement for Santa Cruz Biotechnology antibody catalog# sc-9887 / sc-9888 / sc-20812

Forms a water-specific channel. Osmoreceptor which regulates body water balance and mediates water flow within the central nervous system.

4502181

NP_001641.1

NM_001650.5

P55087

Aquaporin-mediated Transport Pathway (1269944); Bile Secretion Pathway (193146); Bile Secretion Pathway (193095); Passive Transport By Aquaporins Pathway (1269945); SIDS Susceptibility Pathways (198901); Spinal Cord Injury Pathway (739007); Transmembrane Transport Of Small Molecules Pathway (1269903); Vasopressin Regulates Renal Water Homeostasis Via Aquaporins Pathway (1269946); Vasopressin-regulated Water Reabsorption Pathway (143700); Vasopressin-regulated Water Reabsorption Pathway (143631)

This gene encodes a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. This protein is the predominant aquaporin found in brain and has an important role in brain water homeostasis. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. A recent study provided evidence for translational readthrough in this gene and expression of an additional C-terminally extended isoform via the use of an alternative in-frame translation termination codon. [provided by RefSeq, Dec 2015]

AQP4: a member of the aquaporin family of intrinsic membrane proteins that function as water-selective channels in the plasma membranes of many cells. The predominant aquaporin found in brain. Two alternatively spliced transcript variants have been described. Protein type: Channel, misc.; Transporter; Membrane protein, multi-pass; Transporter, aquaporin family; Membrane protein, integral. Chromosomal Location of Human Ortholog: 18q11.2-q12.1. Cellular Component: basolateral plasma membrane; cytoplasm; external side of plasma membrane; integral to membrane; plasma membrane. Molecular Function: glycerol channel activity; water channel activity; water transporter activity. Biological Process: glycerol transport; multicellular organismal water homeostasis; renal water homeostasis; transmembrane transport; transport; water transport

0.05毫升

120美元

0.1毫升

160