产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
Recombinant HIV-1 nef
目录 :
MBS142611
规格 :
0.1毫克
价格 :
225美元
更多信息或购买 :
产品信息
目录号 :
MBS142611
产品类型 :
重组蛋白
产品全称 :
Recombinant HIV-1 nef
产品简称 :
HIV-1 nef
产品名称同义词 :
HIV-1 nef; HIV-1 nef Recombinant; HIV-1 nef
宿主 :
大肠杆菌
序列 :
kwskssv igwptvrerm rraepaadgv gaasqdlekh gaitssntaa tnadcawleaqeeeevgfpv tpqvplrpmt ykaavdlshf lkekgglegl ihsqrrqdil dlwiyhtqgyfpdwqnytpg pgirypltfg wcyklvpvep ekleeankge ntsllhpvsl hgmddperevlewrfdsrla.
特异性 :
HIV-1 nef is immunoreactive with all sera of HIV-1 infected individuals.
纯度 :
Greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
形式 :
HIV-1 nef protein solution in 8M urea, 20mM Tris-HCl pH 8.0, 10mM b-mercaptoethanol. Sterile filtered colorless clear solution.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
应用笔记 :
HIV-1 nef antigen in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
产品种类 :
病毒ANTIGENS-人类IMMUNODEFICIENCY病毒;病毒抗原;艾滋病毒
产品描述 :
Description: The E Coli derived 20 kDa recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 nef immunodominant regions, 3-190 amino acids. The HIV-1 nef is fused to beta-galactosidase (114 kDa) at the N-terminus. Introduction: Human immunodeficiency virus (HIV) is a retrovirus that can lead to a condition in which the immune system begins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the human immune system such as helper T cells (specifically CD4+ T cells), macrophages and dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosis in infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytes that recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunity is lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genome is converted to double-stranded DNA by a virally encoded reverse transcriptase that is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integrase so that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latent and the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells.
尺寸1 :
0.1毫克
价格1 :
225美元
尺寸2 :
0.5毫克
价格2 :
645
size3 :
1毫克
价格3 :
1220
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。