产品简要
公司名称 :
MyBioSource
产品类型 :
蛋白
产品名称 :
重组艾滋病毒-I p24压制
目录 :
MBS142610
规格 :
0.1毫克
价格 :
225美元
更多信息或购买 :
产品信息
目录号 :
MBS142610
产品类型 :
重组蛋白
产品全称 :
重组艾滋病毒-I p24压制
产品简称 :
艾滋病毒-I p24压制
产品名称同义词 :
艾滋病毒-1 p24压制;艾滋病毒-1 p24压制重组;艾滋病毒-1 p24压制
宿主 :
大肠杆菌
序列 :
slyn tvatlycvhq rieikdtkea ldkikeeqnk skkkaqqaaa dtghssqvsq nypivqniqg qmvhqaispr tlnawvkvve ekafspevip mfsalsegat pqdlntmlnt vgghqaamqm lketineeaa ewdrvhpvha gpiapgqmre prgsdiagtt stlqeqigwm tnnppipvge iykrwiilgl nkivrmyspt sildirqgpk epfrdyvdrf yktlraeqas qevknwmtet llvqnanpdc ktilkalgpa atleemmtac qgvggpghka rvlaeamsqv tnsatimmqr gnfrnqrkiv kcfncgkegh iarncraprk kgcwkcgkeg hqmkdcterq anflgk.
特异性 :
Immunoreactive with all sera of HIV-1 infected individuals.
纯度 :
Greater than 95.0% as determined by HPLC analysis and SDS-PAGE.
形式 :
8M urea, 20mM Tris-HCl pH-8 & 10mM b-mercaptoethanol. Sterile filtered colorless clear solution.
检测过的应用 :
酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)
应用笔记 :
HIV-1 p24 gag antigen in ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.
产品种类 :
病毒ANTIGENS-人类IMMUNODEFICIENCY病毒;病毒抗原;艾滋病毒
产品描述 :
Description: The E Coli derived 39 kDa recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 p24 gag immunodominant regions, 77-436 amino acids.The HIV-1 p24 gag is fused to beta-galactosidase (114 kDa). Introduction: Human immunodeficiency virus (HIV) is a retrovirusthat can lead to a condition in which the immune systembegins to fail, leading to opportunistic infections. HIV primarily infects vital cells in the humanimmune systemsuch as helper T cells(specifically CD4+ T cells), macrophagesand dendritic cells. HIV infection leads to low levels of CD4+ T cells through three main mechanisms: firstly, direct viral killing of infected cells; secondly, increased rates of apoptosisin infected cells; and thirdly, killing of infected CD4+ T cells by CD8 cytotoxic lymphocytesthat recognize infected cells. When CD4+ T cell numbers decline below a critical level, cell-mediated immunityis lost, and the body becomes progressively more susceptible to opportunistic infections. HIV was classified as a member of the genus Lentivirus, part of the family of Retroviridae. Lentiviruses have many common morphologies and biological properties. Many species are infected by lentiviruses, which are characteristically responsible for long-duration illnesses with a long incubation period. Lentiviruses are transmitted as single-stranded, positive-sense, enveloped RNA viruses. Upon entry of the target cell, the viral RNA genomeis converted to double-stranded DNAby a virally encoded reverse transcriptasethat is present in the virus particle. This viral DNA is then integrated into the cellular DNA by a virally encoded integraseso that the genome can be transcribed. Once the virus has infected the cell, two pathways are possible: either the virus becomes latentand the infected cell continues to function, or the virus becomes active and replicates, and a large number of virus particles are liberated that can then infect other cells.
规格 :
0.1毫克
价格 :
225美元
更多信息或购买 :
公司信息
![logo](http://aws.labome.com/img/977.gif)
MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。