蛋白

Recombinant HIV-1 pol Integrase

MBS142609

0.1毫克

225美元

重组蛋白

Recombinant HIV-1 pol Integrase

HIV-1 pol Integrase

艾滋病毒-1整合酶类;艾滋病毒-1整合酶类重组;艾滋病毒-1整合酶类

大肠杆菌

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scdkcqlkgeamhgqvdcspgiwqldcthlegkvilvav
hvasgyieaevipaetgqetayfilklagrwpvktihtd
ngsnftsttvkaacwwagikqefgipynpqsqgviesmn
kelkkiigqvrdqaehlktavqmavfihnfkrkggiggy
sagerivdiiatdiqtkelqkqitkiqnfrvyyrdsrdp
lwkgpakllwkgegavviqdnsdikvvprrkakiirdyg
kqmagddcvasrqdedhhhhhh.

Immunoreactive with all sera of HIV-1 infected individuals.

Greater than 95.0% as determined by SDS-PAGE.

1.5M urea, 25mM Tris-HCl pH 8.0, 0.2% Triton-X & 50% Glycerol. Sterile filtered colorless clear solution.

4.55毫克/1毫升

酶联免疫吸附测定(EIA), 免疫印迹(免疫印迹)

HIV-1 Integrase antigen is suitable for ELISA and Western blots, excellent antigen for early detection of HIV seroconvertors with minimal specificity problems.

病毒ANTIGENS-人类IMMUNODEFICIENCY病毒;病毒抗原;艾滋病毒

Description: The E Coli derived 36 kDa recombinant protein is a non-glycosylated polypeptide chain, containing the HIV-1 immunodominant regions from the pol protein (intergrase) and fused with a six histidines tag. Introduction: Integrase is an enzyme produced by the HIV which enables its genetic material to be integrated into the DNA of the infected cell and is a key component in the pre-integration complex. HIV integrase contains 3 domains, an N-terminal HH-CC zinc fingerdomainwhich is partially responsible for multimerization, a central catalytic domain and a C-terminal domain. Both Central catalytic domain and C-terminal domains have been shown to bind both viral and cellular DNA. No crystal structure data exists with Integrase bound to its DNA substrates. HIV-1 integrase functions as a dimeror a tetramer. Additionally, several host cellular proteins interact with integrase and may facilitate the integration process.

0.1毫克

225美元

0.5毫克

645

1毫克

1220