产品简要
公司名称 :
MyBioSource
产品类型 :
ELISA/assay
产品名称 :
兔血管内皮生长因子受体2酶联免疫吸附试剂盒
目录 :
MBS027756
规格 :
48-Strip-Wells
价格 :
470美元
更多信息或购买 :
产品信息
目录号 :
MBS027756
产品类型 :
酶联免疫吸附试剂盒
产品全称 :
兔血管内皮生长因子受体2酶联免疫吸附试剂盒
产品简称 :
[血管内皮生长因子受体2]
其他名称 :
[vascular endothelial growth factor receptor 2; Vascular endothelial growth factor receptor 2; vascular endothelial growth factor receptor 2; soluble VEGFR2; fetal liver kinase 1; fetal liver kinase-1; protein-tyrosine kinase receptor Flk-1; tyrosine kinase growth factor receptor; kinase insert domain receptor (a type III receptor tyrosine kinase); Fetal liver kinase 1; FLK-1; Kinase insert domain receptor; KDR; Protein-tyrosine kinase receptor flk-1]
产品基因名称 :
[VEGFR2]
其他基因名称 :
[激酶插入区受体;激酶插入区受体;FLK1;CD309;VEGFR;VEGFR2;FLK1;VEGFR2;VEGFR-2;FLK-1;激酶插入区受体]
UniProt数据库进入名 :
VGFR2_HUMAN
反应物种 :
兔
特异性 :
No significant cross-reactivity or interference between this analyte and analogues is observed.
储存稳定性 :
Store all reagents at 2-8 degree C
其它信息1 :
Samples: Serum, Plasma and Tissue Homogenate. Assay Type: Sandwich. Detection Range: 6.25 ng/ml - 200 ng/ml. Sensitivity: 1.0 ng/ml.
其他信息2 :
Intra-assay Precision: Intra-assay CV (%) is less than 15%. Inter-assay Precision: Inter-assay CV (%) is less than 15%. [CV(%) = SD/mean ×100].
产品描述 :
Background: This Quantitative Sandwich ELISA kit is only for in vitro research use only, not for drug, household, therapeutic or diagnostic applications! This kit is intended to be used for determination the level of VEGFR2 (hereafter termed this analyte) in undiluted original Rabbit serum, plasma and tissue homogenate samples.
NCBI GI登录号 :
11321597
NCBI登录号 :
NP_002244.1
NCBI基因登录号 :
NM_002253.2
UniProt数据库登录号 :
P35968
NCBI分子量 :
151,527 Da
NCBI信号通路 :
Angiogenesis Pathway (198772); Cardiac Progenitor Differentiation Pathway (712094); Cytokine-cytokine Receptor Interaction Pathway (83051); Cytokine-cytokine Receptor Interaction Pathway (460); Endocytosis Pathway (102279); Endocytosis Pathway (102181); Focal Adhesion Pathway (198795); Focal Adhesion Pathway (83067); Focal Adhesion Pathway (478); HIF-2-alpha Transcription Factor Network Pathway (137956)
NCBI总结 :
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas. [provided by RefSeq, May 2009]
UniProt数据库总结 :
VEGFR2: a receptor tyrosine kinase of the VEGFR family. High affinity receptor for VEGF and VEGF-C. Ligand binding induces autophosphorylation and activation. Activated receptor recruits proteins including Shc, GRB2, PI3K, Nck, SHP-1 and SHP-2. Plays a key role in vascular development and regulation of vascular permeability. Protein type: Kinase, protein; EC 2.7.10.1; Protein kinase, TK; Membrane protein, integral; Protein kinase, tyrosine (receptor); TK group; VEGFR family. Chromosomal Location of Human Ortholog: 4q11-q12. Cellular Component: Golgi apparatus; endoplasmic reticulum; integral to plasma membrane; early endosome; cytoplasmic membrane-bound vesicle; extracellular region; plasma membrane; nucleus; cell junction; endosome; lipid raft; external side of plasma membrane. Molecular Function: integrin binding; vascular endothelial growth factor receptor activity; protein binding; growth factor binding; protein-tyrosine kinase activity; Hsp90 protein binding; receptor signaling protein tyrosine kinase activity; transmembrane receptor protein tyrosine kinase activity; ATP binding. Biological Process: extracellular matrix organization and biogenesis; positive regulation of positive chemotaxis; peptidyl-tyrosine phosphorylation; viral reproduction; protein amino acid autophosphorylation; cell maturation; calcium ion homeostasis; regulation of cell shape; positive regulation of MAPKKK cascade; ovarian follicle development; positive regulation of focal adhesion formation; positive regulation of mesenchymal cell proliferation; positive regulation of cell proliferation; angiogenesis; vasculogenesis; endothelial cell differentiation; cell fate commitment; embryonic hemopoiesis; positive regulation of phosphoinositide 3-kinase cascade; positive regulation of angiogenesis; branching morphogenesis of a tube; cell migration during sprouting angiogenesis; positive regulation of endothelial cell proliferation; positive regulation of protein amino acid phosphorylation; lymph vessel development; vascular endothelial growth factor receptor signaling pathway; alveolus development; surfactant homeostasis; transmembrane receptor protein tyrosine kinase signaling pathway; positive regulation of nitric-oxide synthase biosynthetic process; positive regulation of cell migration; negative regulation of apoptosis. Disease: Hemangioma, Capillary Infantile
尺寸1 :
48-Strip-Wells
价格1 :
470美元
尺寸2 :
96-Strip-Wells
价格2 :
680
size3 :
5x96-Strip-Wells
价格3 :
3100
size4 :
10x96-Strip-Wells
price4 :
6095
更多信息或购买 :
公司信息
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MyBioSource
P.O. Box 153308
San Diego, CA 92195-3308
San Diego, CA 92195-3308
sales@mybiosource.com
https://www.mybiosource.com1-858-633-0165
公司总部: 美国
MyBioSource,LLC最初由三名热情澎湃的提供高品质试剂的科学家联合创立于温哥华,公司愿景是“生物研究试剂的源头”,现在位于圣地亚哥市。
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