抗体

磷酸化PKA RII甲(Ser99)抗体

HY-P80847

100微升;10微升;50微升

300;70;185美元

多克隆

domestic rabbit

未共轭

磷酸化PKA RII甲(Ser99)抗体

抗体

兔

多克隆抗体

Non-conjugated

100微升;10微升;50微升

300;70;185美元

Phospho-PKA RII alpha (Ser99) Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 46 kDa, targeting to Phospho-PKA RII alpha (Ser99). It can be used for WB,IHC-P,ICC/IF,IP assays with tag free, in the background of Human, Mouse, Rat, Pig.

人类, 小鼠, 大鼠, 猪

PKA RII alpha: cAMP is a signaling molecule important for a variety of cellular functions. cAMP exerts its effects by activating the cAMP-dependent protein kinase, which transduces the signal through phosphorylation of different target proteins. The inactive kinase holoenzyme is a tetramer composed of two regulatory and two catalytic subunits. cAMP causes the dissociation of the inactive holoenzyme into a dimer of regulatory subunits bound to four cAMP and two free monomeric catalytic subunits. Four different regulatory subunits and three catalytic subunits have been identified in humans. The protein encoded by this gene is one of the regulatory subunits. This subunit can be phosphorylated by the activated catalytic subunit. It may interact with various A-kinase anchoring proteins and determine the subcellular localization of cAMP-dependent protein kinase. This subunit has been shown to regulate protein transport from endosomes to the Golgi apparatus and further to the endoplasmic reticulum (ER). [provided by RefSeq, Jul 28]

Synthetic phosphopeptide corresponding to residues surrounding Ser99 of Human Phospho-PKA R2.AA range:436-485.

>98%

Supplied in phosphate buffered saline (pH 7.4), 150 mM NaCl and 50% glycerol. Preservative: 0.02% sodium azide

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.