抗体

细胞周期蛋白E1抗体

HY-P80635

10微升;100微升;50微升

70;300;185美元

多克隆

domestic rabbit

未共轭

细胞周期蛋白E1抗体

抗体

兔

多克隆抗体

Non-conjugated

10微升;100微升;50微升

70;300;185美元

Cyclin E1 Antibody is a non-conjugated and Rabbit origined polyclonal antibody about 47 kDa, targeting to Cyclin E1. It can be used for WB,IHC-F,IHC-P,ICC/IF,ELISA assays with tag free, in the background of Human, Mouse, Rat.

人类, 小鼠, 大鼠

Cyclin E1: The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK2, whose activity is required for cell cycle G1/S transition. This protein accumulates at the G1-S phase boundary and is degraded as cells progress through S phase. Overexpression of this gene has been observed in many tumors, which results in chromosome instability, and thus may contribute to tumorigenesis. This protein was found to associate with, and be involved in, the phosphorylation of NPAT protein (nuclear protein mapped to the ATM locus), which participates in cell-cycle regulated histone gene expression and plays a critical role in promoting cell-cycle progression in the absence of pRB. [provided by RefSeq, Apr 216]

合成多肽对应于人的细胞周期蛋白E1.氨基酸range:91-140

>98%

Supplied in 1*PBS (pH 7.3), 50% glycerol and 0.5% BSA. Preservative: 0.02% sodium azide.

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.