产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
人类CENPW合成肽
目录 :
PEP-1483
规格 :
50微克
价格 :
美国159.00
更多信息或购买 :
产品信息
产品类型 :
多肽
产品名称 :
人类CENPW合成肽
目录# :
PEP-1483
规格 :
50微克
价格 :
美国159.00
克隆性 :
Synthetic
纯度 :
纯化
反应物种 :
人类
应用 :
Blocking Assay: Assay-dependent, Control: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
CENPW was initially identified as a gene that was upregulated in multiple cancers, and whose overexpression in mouse fibroblast cells gave rise to distinct cancer-specific phenotypes. It was later found to be a nuclear protein that associated with CENPT, a component of CENPA nucleosome complex in the centromere, and is required for proper kinetochore function. CENPW also specifically interacts with the nucleolar phosphoprotein nucleophosmin, also known as B23 It has been suggested that nucleophosmin functions in the assembly of the kinetochore by interacting with CENPW during interphase. Overexpression of CENPW in the SKOV-3 human ovarian cancer cell line as well as in the zebrafish embryo led to apoptosis, suggesting that high levels of CENPW induces apoptotic cell death.
格式 :
液体
应用w/稀释 :
Blocking Assay: Assay-dependent, Control: Assay-dependent
别名 :
2610036L11Rik; C6orf173; cancer-upregulated gene 2; cancer-up-regulated gene 2 protein; CANP-W; Cenpw; CENP-W; Centromere protein W; Cug2
更多信息或购买 :
公司信息
赛默飞世尔