产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
蛋白
产品名称 :
人类STIM1合成肽
目录 :
PEP-0488
规格 :
50微克
价格 :
美国159.00
更多信息或购买 :
产品信息
产品类型 :
多肽
产品名称 :
人类STIM1合成肽
目录# :
PEP-0488
规格 :
50微克
价格 :
美国159.00
克隆性 :
Synthetic
纯度 :
纯化
反应物种 :
人类
应用 :
Blocking Assay: Assay-dependent, Control: Assay-dependent
物种 :
人类
储存 :
-20°C
描述 :
STIM1 (stromal interacting molecule; also known as GOK) acts as a sensor of calcium depletion within the endoplasmic reticulum and transduces the signal to Orai1, the presumptive CRAC channel at the plasma membrane. Following decrease of luminal calcium concentration, STIM1 oligomerizes and induces Orai1 to enable entry of extracellular calcium into the cytoplasm. However, the precise mechanism of STIM1-Orai1 interaction has not been elucidated yet. Many questions also remain to be solved around STIM1 functional distribution. It turns out that STIM1 associates with growing ends of microtubules and is involved in endoplasmic reticulum tubule extension.
格式 :
液体
应用w/稀释 :
Blocking Assay: Assay-dependent, Control: Assay-dependent
别名 :
D11S4896E; GOK; IMD10; RGD:1306831}; SIM; Stim1; stim1 {ECO:0000312; STIM1L; STRMK; Stromal interaction molecule 1; stromal interaction molecule 1 precursor; TAM; TAM1
更多信息或购买 :
公司信息
赛默飞世尔