NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience

抗体

PBX1多克隆抗体

PA5-82100

100微升

美国500.00

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学

PBX1多克隆抗体

PA5-82100

100微升

美国500.00

多克隆

Anitgen affinity chromatography, Antigen affinity chromatography

兔

人类, 小鼠, 大鼠

Immunocytochemistry: 0.25-2 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.04-0.4 µg/mL

人类, 小鼠, 大鼠

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

This gene encodes a nuclear protein that belongs to the PBX homeobox family of transcriptional factors. Studies in mice suggest that this gene may be involved in the regulation of osteogenesis, and required for skeletal patterning and programming. A chromosomal translocation, t(1; 19) involving this gene and TCF3/E2A gene, is associated with pre-B-cell acute lymphoblastic leukemia. The resulting fusion protein, in which the DNA binding domain of E2A is replaced by the DNA binding domain of this protein, transforms cells by constitutively activating transcription of genes regulated by the PBX protein family. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Recombinant protein corresponding to Human PBX1

液体

Immunocytochemistry: 0.25-2 µg/mL, Immunohistochemistry: 1:200-1:500, Western Blot: 0.04-0.4 µg/mL

2310056B04Rik; D230003C07Rik; DKFZp686B09108; Homeobox protein PBX1; homeobox protein PRL; MGC126627; OTTHUMP00000032205; PBX homeobox 1; Pbx1; Pbx-1; pre B cell leukemia homeobox 1; pre-B-cell leukemia homeobox 1; pre-B-cell leukemia transcription factor 1; PRL