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抗体

神经纤毛蛋白1多克隆抗体

PA5-81295

100微升

美国299.00

多克隆

domestic rabbit

未共轭

免疫组化, 免疫组化-石蜡切片

神经纤毛蛋白1多克隆抗体

PA5-81295

100微升

美国299.00

多克隆

抗原亲和色谱, 蛋白质A

兔

小鼠

免疫组化(石蜡): 1:200-1:1, 000

小鼠

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Neuropilin 1 is a 923 amino acid containing membrane bound coreceptor to a tyrosine kinase receptor belonging to the neuropilin family with two CUB domains, two F5/8 type C domains and a MAM domain. Neuropilin 1 forms a heterodimer with NRP2 (Neuropilin 2) and is known to bind to plexin (PLXNB1) to form semaphorin receptors. Expressed mostly in the nervous system this receptor is implicated in a wide range of functions including in the development of the cardiovascular system, angiogenesis, repulsive axon guidance, formation of certain neuronal circuits, cell survival, control of neuronal migration and organogenesis outside the nervous system. This semaphorin receptor functions as receptors for both the semaphorins and vascular endothelial growth factor and is also a regulator of VEGF-induced angiogenesis. Neuropilin 1 may be involved in aggressive advanced prostate carcinoma and in the progression of breast cancer.

A synthetic peptide corresponding to the center region of the Mouse Neuropilin-1/NRP1

液体

免疫组化(石蜡): 1:200-1:1, 000

A5 protein; BDCA4; C530029I03; CD304; Neuropilin; neuropilin 1; Neuropilin1; neuropilin-1; Neuropilin-1 precursor (A5 protein); NP1; NP-1; Npn1; NPN-1; NRP; NRP 1; Nrp1; sNRP 1; sNRP1; soluble NRP 1; soluble NRP1; transmembrane receptor; vascular endothelial cell growth factor 165 receptor; VEGF165R