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抗体

IKBIP多克隆抗体

PA5-58491

100微升

美国496.00

多克隆

domestic rabbit

未共轭

免疫印迹, 免疫组化

IKBIP多克隆抗体

PA5-58491

100微升

美国496.00

多克隆

抗原亲和色谱

兔

人类

Immunohistochemistry: 1:2,500-1:5,000, Western Blot: 0.04-0.4 µg/mL

人类

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

IKIP (Inhibitor of nuclear factor kappa-B kinase-interacting protein, IKK-interacting protein) is a single-pass membrane protein that shares a common promoter with APAF1. APAF1 and IKIP are both induced by X irradiation, however, the two gene products are transcribed in different directions. The IKIP gene is believed to be a target for p53 as expression of IKIP has been shown to promote apoptosis. IKIP has four known isoforms, three of which are found traversing the endoplasmic reticulum membrane. IKIP isoform 4 has a deletion of the transmembrane region which leads to a homogenous distribution of the protein within the cell. The IKIP gene products are expressed in vascular endothelial cells, while the isoform 4 has also been detected in lung, kidney, spleen, thymus and skeletal muscle.

Recombinant protein corresponding to Human IKBIP

液体

Immunohistochemistry: 1:2,500-1:5,000, Western Blot: 0.04-0.4 µg/mL

1200009F10Rik; 1700023M03Rik; D18354; I kappa B kinase interacting protein; i kappa-B kinase interacting protein; i kappa-B kinase-interacting protein; Ikbip; IKBKB interacting protein; IKBKB-interacting protein; Ikip; IKK interacting protein; IKK-interacting protein; inhibitor of nuclear factor kappa-B kinase-interacting protein