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抗体

胱氨酸-天冬氨酸蛋白酶4/5 p20(切断的Asp270, Asp311)多克隆抗体

PA5-39873

100微克

美国436.00

多克隆

domestic rabbit

未共轭

胱氨酸-天冬氨酸蛋白酶4/5 p20(切断的Asp270, Asp311)多克隆抗体

PA5-39873

100微克

美国436.00

多克隆

抗原亲和色谱

兔

人类

Western Blot: 1:500-1:1,000

人类

IgG

-20°C

This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes composed of a prodomain and a large and small protease subunit. Activation of caspases requires proteolytic processing at conserved internal aspartic residues to generate a heterodimeric enzyme consisting of the large and small subunits. This caspase is able to cleave and activate its own precursor protein, as well as caspase 1 precursor. When overexpressed, this gene induces cell apoptosis. Alternative splicing results in transcript variants encoding distinct isoforms.

A synthetic peptide derived from human Caspase 4/5

液体

Western Blot: 1:500-1:1,000

apoptotic cysteine protease Mih1/TX; CASP4; CASP-4; CASP5; CASP-5; caspase 4; caspase 4, apoptosis-related cysteine peptidase; caspase 4, apoptosis-related cysteine protease; caspase 5; caspase 5, apoptosis-related cysteine peptidase; caspase 5, apoptosis-related cysteine protease; caspase-4; Caspase-4 subunit 1; Caspase-4 subunit 2; Caspase-5; Caspase-5 subunit p10; Caspase-5 subunit p20; ICE and Ced-3 homolog 2; ICE(rel)II; ICE(rel)-II; ICE(rel)III; ICE(rel)-III; ICEREL-II; ICEREL-III; ICH2; ICH-2; ICH3; ICH-3; Mih1; Mih1/TX; protease ICH-2; protease ICH-3; protease protease ICE(rel)III; protease protease TY; Protease TX; protease TY; TX; TY protease