产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化MECP2(Ser421)多克隆抗体
目录 :
PA5-35396
规格 :
100微升
价格 :
美国460.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 2
| 参考文献 |
|---|
产品信息
产品类型 :
抗体
产品名称 :
磷酸化MECP2(Ser421)多克隆抗体
目录# :
PA5-35396
规格 :
100微升
价格 :
美国460.00
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
小鼠, 大鼠
应用 :
Western Blot: 1:1,000
物种 :
小鼠, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
MECP2 belongs to a family of nuclear proteins (including MBD1, MBD2, MBD3 and MBD4) that have a methyl-CpG binding domain. MECP2 is capable of binding specifically to methylated DNA. DNA methylation is the major modification of eukaryotic genomes and plays an essential role in mammalian development. MECP2 can also repress transcription from methylated gene promoters. In contrast to other MBD family members, MECP2 is X-linked and subject to X inactivation. MECP2 is dispensible in stem cells, but is essential for embryonic development. MECP2 gene mutations are the cause of most cases of Rett syndrome, a progressive neurologic developmental disorder and one of the most common causes of mental retardation in females.
免疫原 :
Synthetic phospho-peptide corresponding to amino acid residues surrounding Ser421 of mouse MeCP2 conjugated to KLH
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
1500041B07Rik; AUTSX3; D630021H01Rik; DKFZp686A24160; Mbd5; MECP2; MeCp-2 protein; methyl CpG binding protein 2; methyl-CpG binding protein 2; methyl-CpG-binding protein 2; MRX16; MRX79; MRXS13; MRXSL; PPMX; RS; RTS; RTT; testis tissue sperm-binding protein Li 41a; WBP10
更多信息或购买 :
公司信息
赛默飞世尔