产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
MYO1A多克隆抗体
目录 :
PA5-29084
规格 :
100微升
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
图像
图像 1 :
Immunohistochemical analysis of paraffin-embedded Colon carcinoma using myosin IA (PA5-29084) antibody at 1:500 dilution.
图像 2 :
Western Blot analysis using anti-myosin IA Polyclonal Antibody on the following cells: (30 ug of whole cell lysate) A: Jurkat B: Raji C: K562 D: NCI-H929. Primary antibody (PA5-29084) diluted at 1:2000
产品信息
产品类型 :
抗体
产品名称 :
MYO1A多克隆抗体
目录# :
PA5-29084
规格 :
100微升
价格 :
美国456.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
物种 :
人类
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
The protein encoded by this gene belongs to the myosin superfamily. Myosins are molecular motors that, upon interaction with actin filaments, utilize energy from ATP hydrolysis to generate mechanical force. Each myosin has a conserved N-terminal motor domain that contains both ATP-binding and actin-binding sequences. Following the motor domain is a light-chain-binding 'neck' region containing 1-6 copies of a repeat element, the IQ motif, that serves as a binding site for calmodulin or other members of the EF-hand superfamily of calcium-binding proteins. At the C-terminus, each myosin class has a distinct tail domain that serves in dimerization, membrane binding, protein binding, and/or enzymatic activities and targets each myosin to its particular subcellular location. The kidney epithelial cell line, LLC-PK1-CL4 (CL4), forms a well ordered brush border (BB) on its apical surface. Experiments indicate that the brush border population of the encoded protein turns over rapidly, while its head and tail domains interact transiently with the core actin and plasma membrane, respectively. A rapidly exchanging pool of the protein encoded by this gene envelops an actin core bundle that, by comparison, is static in structure.
免疫原 :
Recombinant fragment corresponding to a region within amino acids 299 and 547 of Human myosin IA
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 1:100-1:1,000, Western Blot: 1:500-1:3,000
别名 :
BBMI; BBM-I; brush border myosin 1; brush border myosin I; brush border myosin-I; DFNA48; MIHC; Myh1; MYHL; Myo1a; myosin heavy polypeptide 1 skeletal muscle adult; myosin I heavy chain; myosin IA; myosin, heavy polypeptide-like (100kD); myosin, heavy polypeptide-like (110kD); myosin-Ia; unconventional myosin-Ia
更多信息或购买 :
公司信息
赛默飞世尔