产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ETS1多克隆抗体
目录 :
PA5-24211
规格 :
400微升
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
图像
图像 1 :
Western blot analysis of ETS1 in Jurkat cell line lysates using 35ug per lane of antibody.
图像 2 :
图像 3 :
Flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
产品信息
产品类型 :
抗体
产品名称 :
ETS1多克隆抗体
目录# :
PA5-24211
规格 :
400微升
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱, 蛋白质A
宿主 :
兔
反应物种 :
人类
应用 :
Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Western Blot: 1:1,000
物种 :
人类
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
ETS1 (c-Ets-1; v-ets erythroblastosis virus E26 oncogene homlog 1 (avian); ETS-1; EWSR2; p54), a 441 A. A protein, is a member of DNA-binding ETS protein family. It is a multifunctional protein consisting of an N-terminal pointed domain, a central transactivation domain and 2 auto inhibitory domains flanked on both sides of conserved C-terminal Ets domain. It interacts with factors including PEBP2alphaA, p300/CBP and mediates transactivation of Osteopontin, Presenilin-1, Stromelysin and Collagenase. It is activated by Ras/MAPK signaling and its expression is up-regulated in resting T-cells. Its activity is modulated by various factors including AP-1, Sp-1, c-myb and MafB. Sp100 activates ETS1 in nuclear bodies. It interacts with EAP1/Daxx and causes repression of MMP1 and BCL2 transactivation. It interacts with STAT6 and modulates Socs-1 expression induced by IL-4. It interacts with GATA3 and positively regulates Tax-1 dependent IL-5 expression.
免疫原 :
KLH conjugated synthetic peptide between 43-70 amino acids from the N-terminal region of human ETS1
格式 :
液体
应用w/稀释 :
Flow Cytometry: 1:10-1:50, Immunocytochemistry: 1:10-1:50, Western Blot: 1:1,000
别名 :
AI196000; AI448617; Avian erythroblastosis virus E26 (v-ets) oncogene homolog-1; avian erythroblastosis virus E26 oncogene 1; c-ets protein; c-ets1; c-ets-1; c-ets-1 oncogene; c-ets-1 protein; c-ets-alpha; c-ets-beta; D230050P06; E26 avian leukemia oncogene 1, 5' domain; Ets avian erythroblastosis virus E2 oncogene homolog 1 (tumor progression locus 1); ets protein; ETS proto-oncogene 1, transcription factor; Ets1; ETS-1; ETS-1A; ETS-1B; Ets-1Delta(III-VI); Etsoncb; EWSR2; FLJ10768; oncoprotein; p54; p54 transcription factor; protein C-ets-1; TNFAIP3 interacting protein 1; TNIP1; Tpl1; transforming protein p54/c-ets-1; transforming protein p68/c-ets-1; tumor progression locus 1; unnamed protein product; v-ets avian erythroblastosis virus E2 oncogene homolog 1; v-ets avian erythroblastosis virus E26 oncogene homolog 1; v-ets erythroblastosis virus E26 oncogene homolog 1; virion-associated nuclear-shuttling protein
更多信息或购买 :
公司信息
赛默飞世尔