产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
MKP-1多克隆抗体
目录 :
PA5-17973
规格 :
100微克
价格 :
美国450.00
克隆性 :
多克隆
宿主 :
domestic goat
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 1
图像
图像 1 :
Immunohistochemical staining of paraffin embedded of Human Prostate using PA5-17973 at a concentration of 3.8 ug/ml. The tissue was processed by steamed antigen retrieval with citrate buffer pH 6 and stained with AP.
图像 2 :
Western Blot staining of HeLa cell lysate using PA5-17973 at a concentration of 0.3 ug/ ml, the primary antibody incubation was 1 hour and the detection method was chemiluminescence.
产品信息
产品类型 :
抗体
产品名称 :
MKP-1多克隆抗体
目录# :
PA5-17973
规格 :
100微克
价格 :
美国450.00
克隆性 :
多克隆
纯度 :
硫酸铵沉淀
宿主 :
山羊
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 8 µg/mL, Western Blot: 1-3 µg/mL
物种 :
人类
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
The expression of DUSP1 gene is induced in human skin fibroblasts by oxidative/heat stress and growth factors. It specifies a protein with structural features similar to members of the non-receptor-type protein-tyrosine phosphatase family, and which has significant amino-acid sequence similarity to a Tyr/Ser-protein phosphatase encoded by the late gene H1 of vaccinia virus. The bacterially expressed and purified DUSP1 protein has intrinsic phosphatase activity, and specifically inactivates mitogen-activated protein (MAP) kinase in vitro by the concomitant dephosphorylation of both its phosphothreonine and phosphotyrosine residues. Furthermore, it suppresses the activation of MAP kinase by oncogenic ras in extracts of Xenopus oocytes. Thus, DUSP1 may play an important role in the human cellular response to environmental stress as well as in the negative regulation of cellular proliferation.
免疫原 :
Synthetic peptide sequence (SYLQSPITTSPSC) corresponding to the C-terminus amino acids of DUSP1
格式 :
液体
应用w/稀释 :
Immunohistochemistry (Paraffin): 8 µg/mL, Western Blot: 1-3 µg/mL
别名 :
3ch134; 3CH134/CL100 PTPase; CL 100; CL100; dual specificity phosphatase 1; dual specificity protein phosphatase 1; Dual specificity protein phosphatase hVH1; DUS1; DUSP1; EC 3.1.3.16; EC 3.1.3.48; erp; HVH1; MAP kinase phosphatase 1; MAP kinase phosphatase-1; mitogen-activated protein (MAP) kinase phosphatase-1; mitogen-activated protein kinase phosphatase 1; mitogen-activated protein kinase phosphatase-1; MKP1; mkp-1; oxidative stress-inducible protein tyrosine phosphatase; protein tyrosine phosphatase non-receptor type 16; protein tyrosine phosphatase, non-receptor type 16; protein-tyrosine phosphatase 3CH134; Protein-tyrosine phosphatase CL100; protein-tyrosine phosphatase ERP; Protein-tyrosine phosphatase non-receptor type 16; PTPN10; Ptpn16; serine/threonine specific protein phosphatase; U19515; VH1
更多信息或购买 :
公司信息
赛默飞世尔