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抗体

Phospho-Rb (Ser780) Polyclonal Antibody

PA5-12681

400微升

美国446.00

多克隆

domestic rabbit

未共轭

磷酸化

免疫组化, 免疫组化-石蜡切片, dot blot

Phospho-Rb (Ser780) Polyclonal Antibody

PA5-12681

400微升

美国446.00

多克隆

抗原亲和色谱, 蛋白质A

兔

人类

Dot Blot: 1:500, Immunohistochemistry (Paraffin): 1:50-1:100

人类

IgG

-20° C, 避免反复冷冻/解冻

Rb is a tumor suppressor nuclear phosphoprotein capable of binding to DNA. It is phosphorylated on serine and threonine, but not on tyrosine residues. It forms a complex with SV40 large T antigen, adenovirus E1A, and human papilloma virus-16 E. Rb protein may act by regulating transcription and loss of its function leads to uncontrolled cell growth. Aberrations in the RB gene have been implicated in cancers of breast, colon, prostate, kidney, nasopharynx, and leukemia.

KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S780 of human Rb

液体

Dot Blot: 1:500, Immunohistochemistry (Paraffin): 1:50-1:100

Cleaved Rb; delta RB-p70; DRb-p70; exon 17 tumor GOS561 substitution mutation causes premature stop; GOS563 exon 17 substitution mutation causes premature stop; OSRC; p104; p104 chicken Rb; P105RB; p105-Rb; Phospho-Retinoblastoma; pp105; pp110; PPP1R130; pRb; prepro-retinoblastoma-associated protein; protein phosphatase 1, regulatory subunit 130; rb; RB transcriptional corepressor 1; RB1; Rb-1; Rb-p70; Retin; Retinoblastoma; retinoblastoma 1; retinoblastoma 1 (including osteosarcoma); retinoblastoma 1 protein; retinoblastoma gene; retinoblastoma isoform A; retinoblastoma protein; retinoblastoma suspectibility protein; retinoblastoma tumor suppressor; retinoblastoma-associated protein