产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
B4GALT1多克隆抗体
目录 :
PA5-117139
规格 :
100微升
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类
应用 :
免疫印迹
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
B4GALT1多克隆抗体
目录# :
PA5-117139
规格 :
100微升
价格 :
美国446.00
克隆性 :
多克隆
纯度 :
亲和色谱
宿主 :
兔
反应物种 :
人类
应用 :
Western Blot: 1:500-1:2,000
物种 :
人类
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing.
免疫原 :
Recombinant fusion protein containing a sequence corresponding to amino acids 45-210 of human B4GALT1 (NP_0014882)
格式 :
液体
应用w/稀释 :
Western Blot: 1:500-1:2,000
别名 :
b1,4-Galactosyltransferase I; B-1,4-GalT; B-1,4-GalT1; B4galt1; b4Gal-T1; Beta-1,4-galactosyltransferase 1; beta-1,4-GalT; beta-1,4-GalT1; beta-1,4-GalTase 1; beta4Gal-T1; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; CDG2D; galactosyltransferase 2 beta 1, 4; GalT; Ggtb; GGTB2; glycoprotein galactosyltransferase beta 1, 4; glycoprotein-4-beta-galactosyltransferase 2; Golgi complex; GT1; GTB; lactose synthase; Lactose synthase A protein; N-acetyllactosamine synthase; Nal synthase; Processed beta-1; Processed beta-1,4-galactosyltransferase 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1
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公司信息
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赛默飞世尔