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抗体

B4GALT1多克隆抗体

PA5-117139

100微升

美国446.00

多克隆

domestic rabbit

未共轭

B4GALT1多克隆抗体

PA5-117139

100微升

美国446.00

多克隆

亲和色谱

兔

人类

Western Blot: 1:500-1:2,000

人类

IgG

-20° C, 避免反复冷冻/解冻

This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. This gene is unique among the beta4GalT genes because it encodes an enzyme that participates both in glycoconjugate and lactose biosynthesis. For the first activity, the enzyme adds galactose to N-acetylglucosamine residues that are either monosaccharides or the nonreducing ends of glycoprotein carbohydrate chains. The second activity is restricted to lactating mammary tissues where the enzyme forms a heterodimer with alpha-lactalbumin to catalyze UDP-galactose + D-glucose UDP + lactose. The two enzymatic forms result from alternate transcription initiation sites and post-translational processing.

Recombinant fusion protein containing a sequence corresponding to amino acids 45-210 of human B4GALT1 (NP_0014882)

液体

Western Blot: 1:500-1:2,000

b1,4-Galactosyltransferase I; B-1,4-GalT; B-1,4-GalT1; B4galt1; b4Gal-T1; Beta-1,4-galactosyltransferase 1; beta-1,4-GalT; beta-1,4-GalT1; beta-1,4-GalTase 1; beta4Gal-T1; Beta-N-acetylglucosaminyl-glycolipid beta-1,4-galactosyltransferase; Beta-N-acetylglucosaminylglycopeptide beta-1,4-galactosyltransferase; CDG2D; galactosyltransferase 2 beta 1, 4; GalT; Ggtb; GGTB2; glycoprotein galactosyltransferase beta 1, 4; glycoprotein-4-beta-galactosyltransferase 2; Golgi complex; GT1; GTB; lactose synthase; Lactose synthase A protein; N-acetyllactosamine synthase; Nal synthase; Processed beta-1; Processed beta-1,4-galactosyltransferase 1; UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 1; UDP-Gal:beta-GlcNAc beta-1,4-galactosyltransferase 1; UDP-galactose:beta-N-acetylglucosamine beta-1,4-galactosyltransferase 1