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抗体

UBR4多克隆抗体

PA5-116101

100微升

美国436.00

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化

UBR4多克隆抗体

PA5-116101

100微升

美国436.00

多克隆

亲和色谱

兔

人类, 小鼠, 大鼠

Immunohistochemistry (PFA fixed): 1:50-1:200, Western Blot: 1:500-1:2,000

人类, 小鼠, 大鼠

IgG

-20°C

E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation. Together with clathrin, forms meshwork structures involved in membrane morphogenesis and cytoskeletal organization. Regulates integrin-mediated signaling. May play a role in activation of FAK in response to cell-matrix interactions. Mediates ubiquitination of ACLY, leading to its subsequent degradation.

A synthesized peptide derived from human UBR4(Accession Q5T4S7), corresponding to amino acid residues P4006-A4056.

液体

Immunohistochemistry (PFA fixed): 1:50-1:200, Western Blot: 1:500-1:2,000

1810009A16Rik; 600 kDa retinoblastoma protein-associated factor; A930005E13Rik; D930005K06Rik; E3 ubiquitin-protein ligase UBR4; Gm1032; Gm1666; KIAA0462; KIAA1307; mKIAA0462; N28143; N-recognin-4; p600; Rbaf600; retinoblastoma-associated factor 600; retinoblastoma-associated factor 600-like protein; retinoblastoma-associated factor of 600 kDa; RING-type E3 ubiquitin transferase UBR4; ubiquitin protein ligase E3 component n-recognin 4; UBR4; Zinc finger UBR1-type protein 1; zinc finger, UBR1 type 1; ZUBR1