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抗体

RAB9多克隆抗体

PA5-101027

100微升

美国446.00

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫细胞化学

RAB9多克隆抗体

PA5-101027

100微升

美国446.00

多克隆

亲和色谱

兔

人类, 小鼠, 大鼠

Immunocytochemistry: Assay-dependent, Western Blot: 1:1,000-1:3,000

人类, 小鼠, 大鼠

IgG

-20°C

Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components. It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin.

A synthesized peptide derived from human RAB9A(Accession P51151), corresponding to amino acid residues L72-L122.

液体

Immunocytochemistry: Assay-dependent, Western Blot: 1:1,000-1:3,000

2410064E05Rik; AI195561; rab9; rab9 GTP-binding protein; RAB9, member RAS oncogene family; Rab9a; rab-9A; RAB9A, member RAS oncogene family; RAB9-like protein; ras-related protein Rab-9A; Sid 99; Sid6061p; Sid99