产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Anthrax Protective Antigen Polyclonal Antibody
目录 :
PA1-41081
规格 :
200微升
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
anthrax bacterium
应用 :
免疫印迹
更多信息或购买 :
图像
图像 1 :
产品信息
产品类型 :
抗体
产品名称 :
Anthrax Protective Antigen Polyclonal Antibody
目录# :
PA1-41081
规格 :
200微升
价格 :
美国446.00
克隆性 :
多克隆
宿主 :
兔
反应物种 :
细菌
应用 :
Western Blot: 1:1,000
物种 :
细菌
抗体亚型 :
IgG
储存 :
短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻
描述 :
Anthrax infection is initiated by the inhalation, ingestion, or cutaneous contact with Bacillus anthracis endospores. B. anthracis produces three polypeptides that comprise the anthrax toxin: protective antigen (PA), lethal factor (LF), and edema factor (EF). PA binds to two related proteins on the cell surface; these are termed tumor epithelial marker 8 (TEM8)/anthrax toxin receptor (ATR) and capillary morphogenesis protein 2 (CMG2), although it is still unclear which is physiologically relevant. Following PA binding to its receptor, PA is cleaved into two fragments by a furin-like protease. The bound fragment binds both LF and EF; the resulting complex is then endocytosed which allows the translocation of LF and EF into the cytoplasm. These toxins are usually sufficient to cause rapid cell death, and often the death of the organism.
免疫原 :
Synthetic peptide corresponding to residues 240-254 of the anthrax Pa protein.
格式 :
液体
应用w/稀释 :
Western Blot: 1:1,000
别名 :
炭疽PA
更多信息或购买 :
公司信息
赛默飞世尔