产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
BDNF多克隆抗体
目录 :
PA1-18372
规格 :
500微克
价格 :
美国456.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫组化-冰冻切片
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产品信息
产品类型 :
抗体
产品名称 :
BDNF多克隆抗体
目录# :
PA1-18372
规格 :
500微克
价格 :
美国456.00
克隆性 :
多克隆
纯度 :
蛋白质G
宿主 :
兔
反应物种 :
人类, 大鼠
应用 :
ELISA: 1-10 µg/mL, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1-10 µg/mL, Western Blot: 1-10 µg/mL
物种 :
人类, 大鼠
抗体亚型 :
IgG
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
BDNF (Brain-Derived Neurotrophic Factor) is a member of the neurotrophin family. BDNF is synthesized as pre-proBDNF, followed by cleavage to proBDNF. Although further processing generates the mature, 14 kDa protein, pro-BDNF is biologically active and is secreted in synaptic vesicles along with the mature form. BDNF is widely expressed in the central nervous system and acts in an autocrine and paracrine manner on several classes of neurons. Signaling occurs mainly through the tyrosine kinase receptor TrkB, although binding to the lower-affinity receptor, p75-NTR, has also been demonstrated. BDNF promotes neuronal survival and differentiation and has been shown to play a critical role in memory formation and synaptic regulation. BDNF is induced by cortical neurons, and is necessary for survival of striatal neurons in the brain. Expression of BDNF is reduced in both Alzheimer's and Huntington disease patients, and may also play a role in the regulation of stress response and in the biology of mood disorders.
免疫原 :
合成多肽对应于氨基酸残基H(129)S D P A R R G E L(138)人的BDNF
格式 :
冻干
应用w/稀释 :
ELISA: 1-10 µg/mL, Immunocytochemistry: 1:200, Immunohistochemistry (Frozen): 1-10 µg/mL, Western Blot: 1-10 µg/mL
别名 :
abrineurin; ANON2; anorexia BDNF; Bdnf; BDNF precursor form; bdnf protein; brain derived neurothrophic factor; brain derived neurotrophic factor; brain-derived neurotrophic factor; BULN2; H-BDNF; neurotrophin; ProBDNF
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公司信息
赛默飞世尔