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抗体

RALA重组兔单克隆抗体(JE54-12)

MA5-50740

100微升

美国439.00

重组

domestic rabbit

未共轭

JE54-12

免疫印迹, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片

RALA重组兔单克隆抗体(JE54-12)

MA5-50740

100微升

美国439.00

重组单克隆

蛋白质A

兔

人类

Flow Cytometry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500

人类

JE54-12

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Multifunctional GTPase involved in a variety of cellular processes including gene expression, cell migration, cell proliferation, oncogenic transformation and membrane trafficking. Accomplishes its multiple functions by interacting with distinct downstream effectors. Acts as a GTP sensor for GTP-dependent exocytosis of dense core vesicles. Plays a role in the early stages of cytokinesis and is required to tether the exocyst to the cytokinetic furrow. The RALA-exocyst complex regulates integrin-dependent membrane raft exocytosis and growth signaling. Key regulator of LPAR1 signaling and competes with GRK2 for binding to LPAR1 thus affecting the signaling properties of the receptor. Required for anchorage-independent proliferation of transformed cells.

Recombinant protein within Human RALA aa 107-206/206.

液体

Flow Cytometry: 1:500-1:1,000, Immunohistochemistry (Paraffin): 1:200-1:1,000, Western Blot: 1:500

3010001O15Rik; AW322615; MGC48949; Ral; -ral simian leukemia viral oncogene homolog A (ras related); RALA; Ral-a; ral-A protein; RALA Ras like proto-oncogene A; Ras family small GTP binding protein RALA; ras related GTP binding protein A; Rasl1; RAS-like protein A; RAS-like, family 1; ras-related protein Ral-A; v-ral simian leukemia viral oncogene homolog A (ras related)