产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
PKC theta Monoclonal Antibody (M217)
目录 :
MA5-47677
规格 :
100微升
价格 :
美国499.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
M217
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
PKC theta Monoclonal Antibody (M217)
目录# :
MA5-47677
规格 :
100微升
价格 :
美国499.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:1,000, Western Blot: 1:100
物种 :
人类, 小鼠, 大鼠
克隆 :
M217
抗体亚型 :
IgG2a
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Protein Kinase C (PKC) isoforms are serine/threonine kinases involved in signal transduction pathways that govern a wide range of physiological processes including differentiation, proliferation, gene expression, brain function, membrane transport and the organization of cytoskeletal and extracellular matrix proteins. Increasing evidence from studies using in vitro and in vivo systems points to PKC as a key regulator of critical cell cycle transitions, including cell cycle entry and exit and the G1 and G2 checkpoints. PKC-mediated control of these transitions can be negative or positive, depending on the timing of PKC activation during the cell cycle and on the specific PKC isozymes involve. There have been at least 12 different PKC isoforms identified in humans to date, including alpha, beta I, beta II, gamma, delta, epsilon, zeta, eta, theta, iota, lambda, and mu. The different PKC isoforms vary in structure, subcellular localization, tissue distribution and response to extracellular signals. PKC beta II has been shown to be expressed, in part, in cardiac muscle, intestinal epithelium, kidney and pancreas. PKC beta II has been shown to be involved in cell cycle progression and cancer proliferation.
免疫原 :
Clone (M217) was generated from a recombinant mouse PKC theta protein that included amino acids residues in the N-terminal region. This sequence is conserved in human and rat PKC theta, and has low homology to other PKC family members.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:1,000, Western Blot: 1:100
别名 :
A130035A12Rik; AW494342; EC 2.7.11.13; kinase nPKC-theta; KPCT; MGC126514; MGC141919; nPKC-theta; PKC theta; PKC-0; Pkcq; PKCtheta; PKC-theta; PRKCQ; PRKCT; protein kinase C theta; protein kinase C theta type; protein kinase C, theta; RP11-563J2.1; si:ch211-239o15.1
更多信息或购买 :
公司信息
赛默飞世尔