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抗体

Nestin Monoclonal Antibody (4D11)

MA5-47329

500微升

美国1556.00

单克隆

小鼠

未共轭

4D11

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学

Nestin Monoclonal Antibody (4D11)

MA5-47329

500微升

美国1556.00

单克隆

蛋白质A/G

小鼠

人类, 小鼠, 大鼠

Immunocytochemistry: 1:500, Immunohistochemistry: Assay-dependent, Western Blot: 1:500

人类, 小鼠, 大鼠

4D11

IgG1

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

Recombinant construct, amino acids 317-630 of the human protein expressed in and purified from E. coli.

液体

Immunocytochemistry: 1:500, Immunohistochemistry: Assay-dependent, Western Blot: 1:500

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin