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抗体

磷酸化哺乳动物雷帕霉素靶蛋白(Ser2448)重组兔单克隆抗体(ARC0094)

MA5-35832

100微升

美国460.00

重组

domestic rabbit

未共轭

ARC0094

人类, 小鼠, 大鼠

磷酸化哺乳动物雷帕霉素靶蛋白(Ser2448)重组兔单克隆抗体(ARC0094)

MA5-35832

100微升

美国460.00

重组单克隆

亲和色谱

兔

人类, 小鼠, 大鼠

Western Blot: 1:500-1:2,000

人类, 小鼠, 大鼠

ARC0094

IgG

-20° C, 避免反复冷冻/解冻

FRAP1 (mTOR) is a serine/threonine kinase that plays a critical role in cellular growth and proliferation. Perturbations in the mTOR/PI3-kinase/AKT pathway are associated with numerous forms of cancer. FRAP1 is also the target of rapamycin and its analogues, which are currently used as immunosuppressants and cancer therapeutics. Mutations affecting the gene results in Smith-Kingsmore syndrome.

A synthetic phosphorylated peptide around S2448 of human mTOR (P42345)

液体

Western Blot: 1:500-1:2,000

2610315D21Rik; AI327068; angiopoietin-like factor CDT6; FK506 binding protein 12-rapamycin associated protein 1; FK506 binding protein 12-rapamycin associated protein 2; FK506-binding protein 12-rapamycin complex-associated protein 1; FKBP12-rapamycin complex-associated protein; FKBP12-rapamycin complex-associated protein 1; FKBP-rapamycin associated protein; FKBP-rapamycin associated protein (FRAP); FKBP-rapamycin-associated protein FRAP; flat; FRAP; FRAP1; FRAP2; Mammalian target of rapamycin; mechanistic target of rapamycin; mechanistic target of rapamycin (serine/threonine kinase); mechanistic target of rapamycin kinase; Mtor; m-TOR; mTORC1; Raft1; Rapamycin and FKBP12 target 1; rapamycin and FKBP12 target-1 protein; rapamycin associated protein FRAP2; rapamycin target protein 1; RAPT1; serine/threonine-protein kinase mTOR; SKS