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抗体

磷酸化LAT(Tyr191)重组兔单克隆抗体(2E4)

MA5-33177

100微升

美国450.00

重组

domestic rabbit

未共轭

2E4

免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片

磷酸化LAT(Tyr191)重组兔单克隆抗体(2E4)

MA5-33177

100微升

美国450.00

重组单克隆

蛋白质G

兔

人类

ELISA: Assay-Dependent, Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 1:200-1:1,000, Western Blot: 1:500-1:5,000

人类

2E4

IgG

-20°C or -80°C if preferred

LAT (Linker for Activation of T cells) is a 36-38 kDa double-palmitoylated transmembrane adaptor protein expressed by T cells, pre-B cells, NK cells, mast cells and platelets. After immunoreceptor triggering, LAT becomes multiply tyrosine-phosphorylated by Syk-, Src-, or Tec-family kinases, providing docking sites for downstream signaling molecules. LAT is essential for TCR-dependent T cell- and FcepsilonRI-dependent mast cell activation, as well as for maturation of early thymocytes. It is also involved in NK cell signaling and platelet activation.

A synthesized peptide derived from human Phospho-LAT (Y191)

液体

ELISA: Assay-Dependent, Immunocytochemistry: 1:20-1:200, Immunohistochemistry (Paraffin): 1:50-1:200, Immunoprecipitation: 1:200-1:1,000, Western Blot: 1:500-1:5,000

36 kDa phospho-tyrosine adapter protein; 36 kDa phospho-tyrosine adaptor protein; Lat; LAT1; linker for activation of T cells; linker for activation of T cells, transmembrane adaptor; linker for activation of T-cells; linker for activation of T-cells family member 1; linker protein; p36-38; pp36