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抗体

STAT5甲/乙重组兔单克隆抗体(JJ08-78)

MA5-32452

100微升

美国436.00

重组

domestic rabbit

未共轭

JJ08-78

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

STAT5甲/乙重组兔单克隆抗体(JJ08-78)

MA5-32452

100微升

美国436.00

重组单克隆

蛋白质A

兔

人类, 小鼠, 大鼠

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:50-1:200, Immunohistochemistry: 1:50-1:200, Western Blot: 1:1,000-1:2,000

人类, 小鼠, 大鼠

JJ08-78

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of, many cell ligands, such as IL-2, IL-3, IL-7, GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/ BCL-X(L), which suggests the antiapoptotic function of this gene in cells.

Recombinant protein within mouse Stat5b aa 585-773

液体

Flow Cytometry: 1:50-1:100, Immunocytochemistry: 1:50-1:200, Immunohistochemistry: 1:50-1:200, Western Blot: 1:1,000-1:2,000

AA959963; Mammary gland factor; mammary gland factor STAT5A; mammary gland factor STAT5B; mammary gland factor; transcription factor; MGF; Mpf; signal transducer and activator of transcription 5; Signal transducer and activator of transcription 5a; Signal transducer and activator of transcription 5B; STA5B; STAT; STAT5; Stat5a; Stat5b; transcription factor STAT5B