产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Phospho-Btk (Tyr223) Recombinant Rabbit Monoclonal Antibody (BtkY223-B4), PE
目录 :
MA5-28077
规格 :
100试验
价格 :
美国435.00
克隆性 :
重组
宿主 :
domestic rabbit
共轭标签 :
PE
克隆名称 :
BtkY223-B4
反应物种 :
人类, 小鼠
应用 :
流式细胞仪
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
Phospho-Btk (Tyr223) Recombinant Rabbit Monoclonal Antibody (BtkY223-B4), PE
目录# :
MA5-28077
规格 :
100试验
价格 :
美国435.00
克隆性 :
重组单克隆
纯度 :
蛋白质A/G
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Flow Cytometry: 5 µL/1x10^6 cells
物种 :
人类, 小鼠
克隆 :
BtkY223-B4
抗体亚型 :
IgG, kappa
储存 :
4° C
描述 :
Bruton tyrosine kinase (BTK) is a cytoplasmic tyrosine kinase belonging to the SRC-related TEC subfamily of tyrosine kinases. Mutations in the BTK gene have been linked to severe developmental blocks in human B-cell ontogeny and immunodeficiency disorders. It has recently been shown to interact with members of the toll-like receptor (TLR) family such as TLR4, 6, 8, and 9. The TLRs are critical molecules in both the innate and adaptive immunity and can recognize diverse microbial pathogens. BTK has also been shown to interact with key proteins involved in TLR4 signal transduction such as MyD88, TIRAP, and IRAK, but not TRAF-6, suggesting that BTK is involved in lipopolysaccharide signal transduction.
免疫原 :
A synthetic phospho-peptide corresponding to residues surrounding Tyr223 of human phospho Btk.
格式 :
液体
应用w/稀释 :
Flow Cytometry: 5 µL/1x10^6 cells
别名 :
agammaglobulinaemia tyrosine kinase; agammaglobulinemia tyrosine kinase; AGMX1; AI528679; AT; ATK; B-cell progenitor kinase; BPK; Bruton agammaglobulinemia tyrosine kinase; Bruton tyrosine kinase; Bruton's tyrosine kinase; BTK; dominant-negative kinase-deficient Brutons tyrosine kinase; IMD1; Kinase EMB; MGC126261; MGC126262; OTTHUMP00000023677; PSCTK1; RP1-164F3.2; truncated Bruton agammaglobulinemia tyrosine kinase; tyrosine-protein kinase BTK; Tyrosine-protein kinase BTK (Brutons tyrosine kinase) (Agammaglobulinaemia tyrosine kinase) (ATK) (B cell progenitor kinase) (BPK) (Kinase EMB); tyrosine-protein kinase BTK isoform (lacking exon 13 to 17); tyrosine-protein kinase BTK isoform (lacking exon 14); xid; XLA; X-linked immune deficiency
更多信息或购买 :
公司信息
赛默飞世尔