产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
TAFA5单克隆抗体(463102)
目录 :
MA5-24183
规格 :
100微克
价格 :
美国446.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
463102
反应物种 :
人类
应用 :
免疫印迹, 免疫组化, 免疫组化-石蜡切片
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
TAFA5单克隆抗体(463102)
目录# :
MA5-24183
规格 :
100微克
价格 :
美国446.00
克隆性 :
单克隆
纯度 :
蛋白质A/G
宿主 :
大鼠
反应物种 :
人类
应用 :
Immunohistochemistry (Paraffin): 8-25 µg/mL, Western Blot: 1 µg/mL
物种 :
人类
克隆 :
463102
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Acts as a chemokine-like protein by regulating cell proliferation and migration through activation of G protein-coupled receptors (GPCRs), such as S1PR2 and FPR2. Stimulates chemotactic migration of macrophages mediated by the MAPK3/ERK1 and AKT1 pathway. Blocks TNFSF11/RANKL-induced osteoclast formation from macrophages by inhibiting up-regulation of osteoclast fusogenic and differentiation genes. Stimulation of macrophage migration and inhibition of osteoclast formation is mediated via GPCR FPR2. Acts as an adipokine by negatively regulating vascular smooth muscle cell (VSMC) proliferation and migration in response to platelet-derived growth factor stimulation via GPCR S1PR2 and G protein GNA12/GNA13-transmitted RHOA signaling . Inhibits injury-induced cell proliferation and neointima formation in the femoral arteries
免疫原 :
E. coli-derived recombinant human TAFA5/FAM19A5 Gln26-Ser125
格式 :
冻干
应用w/稀释 :
Immunohistochemistry (Paraffin): 8-25 µg/mL, Western Blot: 1 µg/mL
别名 :
Chemokine-like protein TAFA-5; FAM19A5; family with sequence similarity 19 (chemokine (C-C motif)-like), member A5; family with sequence similarity 19 member A5, C-C motif chemokine like; family with sequence similarity 19, member A5; protein FAM19A5; QLLK5208; RGD1562115; TAFA protein 5; TAFA5; Tafa-5; Tara-5; UNQ5208; UNQ5208/PRO34524
更多信息或购买 :
公司信息
赛默飞世尔