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抗体

Nestin Monoclonal Antibody (10C2), HRP

MA5-16105

100微升

美国456.00

单克隆

小鼠

HRP

10C2

免疫印迹, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片

Nestin Monoclonal Antibody (10C2), HRP

MA5-16105

100微升

美国456.00

单克隆

蛋白质G

小鼠

人类

Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000-1:5,000

人类

10C2

IgG1, kappa

4° C, store in dark

Nestin is a Class VI intermediate filament abundantly produced in the developing central nervous system (CNS) and in early embryonic neuroepithelial stem cells. Nestin has been widely used as a predominant marker for stem/progenitor cells, glioma cells, and tumor endothelial cells. Also, Nestin is a superior angiogenic marker to evaluate neovascularity of endothelial cells in tumors. Highly specific antibodies to human Nestin can aid in characterizing progenitor cells differentiating into distinct lineages, in enhancing the therapeutic potential of human neural stem/progenitor cells in the treatment of CNS diseases or injury, and in identifying neuroepithelial tumor cells. Nestin expression has been observed in pancreatic hematopoietic stem cell populations, and is considered a novel angiogenesis marker of proliferating endothelial cells in colorectal cancer tissue.

A fragment of the human nestin protein corresponding to residues 1464-1614.

液体

Immunohistochemistry (Frozen): 1:100-1:200, Immunohistochemistry (Paraffin): 1:100-1:200, Western Blot: 1:1,000-1:5,000

AA166324; C78523; ESTM46; FLJ21841; intermediate filament protein; Nbla00170; Nes; Nestin