产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞周期蛋白D2单克隆抗体(DCS-3.1)
目录 :
MA5-12712
规格 :
500微升
价格 :
美国344.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DCS-3.1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
文章摘录数: 19
参考文献 |
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Stein J, Milewski W, Hara M, Steiner D, Dey A. GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1). Islets. 2011;3:21-34 pubmed
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Zheng Y, Bie W, Yang R, Perekatt A, Poole A, Tyner A. Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine. Cancer Biol Ther. 2008;7:873-9 pubmed
|
Glickstein S, Moore H, Slowinska B, Racchumi J, Suh M, Chuhma N, et al. Selective cortical interneuron and GABA deficits in cyclin D2-null mice. Development. 2007;134:4083-93 pubmed
|
Andreu Vieyra C, Chen R, Matzuk M. Effects of granulosa cell-specific deletion of Rb in Inha-alpha null female mice. Endocrinology. 2007;148:3837-49 pubmed
|
Pogoriler J, Millen K, Utset M, Du W. Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development. 2006;133:3929-37 pubmed
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Malik A, Afaq F, Sarfaraz S, Adhami V, Syed D, Mukhtar H. Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer. Proc Natl Acad Sci U S A. 2005;102:14813-8 pubmed
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Chen B, Pollard J. Cyclin D2 compensates for the loss of cyclin D1 in estrogen-induced mouse uterine epithelial cell proliferation. Mol Endocrinol. 2003;17:1368-81 pubmed
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Gupta S, Afaq F, Mukhtar H. Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. Oncogene. 2002;21:3727-38 pubmed
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Clark W, Black E, MacLaren A, Kruse U, LaThangue N, Vogt P, et al. v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity. Mol Cell Biol. 2000;20:2529-42 pubmed
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Tsutsui T, Hesabi B, Moons D, Pandolfi P, Hansel K, Koff A, et al. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Mol Cell Biol. 1999;19:7011-9 pubmed
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产品信息
产品类型 :
抗体
产品名称 :
细胞周期蛋白D2单克隆抗体(DCS-3.1)
目录# :
MA5-12712
规格 :
500微升
价格 :
美国344.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL, Western Blot: Assay-dependent
物种 :
人类, 小鼠, 大鼠
克隆 :
DCS-3.1
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.
免疫原 :
纯化人类重组全长细胞周期蛋白D2蛋白
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL, Western Blot: Assay-dependent
别名 :
2600016F06Rik; AI256817; BF642806; C86853; CCND2; cD2; cyclin D2; Cyl-2; G1/S-specific cyclin-D2; KIAK0002; MGC102758; MPPH3; Vin1; Vin-1; Vin-1 proto-oncogene
更多信息或购买 :
公司信息
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赛默飞世尔