产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
细胞周期蛋白D2单克隆抗体(DCS-3.1)
目录 :
MA5-12712
规格 :
500微升
价格 :
美国344.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
DCS-3.1
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
参考文献
Pierozan P, Cattani D, Karlsson O. Perfluorooctane sulfonate (PFOS) and perfluorooctanoic acid (PFOA) induce epigenetic alterations and promote human breast cell carcinogenesis in vitro. Arch Toxicol. 2020;94:3893-3906 pubmed 出版商
Pierozan P, Jernerén F, Karlsson O. Perfluorooctanoic acid (PFOA) exposure promotes proliferation, migration and invasion potential in human breast epithelial cells. Arch Toxicol. 2018;92:1729-1739 pubmed 出版商
Pierozan P, Karlsson O. PFOS induces proliferation, cell-cycle progression, and malignant phenotype in human breast epithelial cells. Arch Toxicol. 2018;92:705-716 pubmed 出版商
Yang Y, Chang B, Chan L. Sustained expression of the transcription factor GLIS3 is required for normal beta cell function in adults. EMBO Mol Med. 2013;5:92-104 pubmed 出版商
Zhang Q, Sakamoto K, Liu C, Triplett A, Lin W, Rui H, et al. Cyclin D3 compensates for the loss of cyclin D1 during ErbB2-induced mammary tumor initiation and progression. Cancer Res. 2011;71:7513-24 pubmed 出版商
Stein J, Milewski W, Hara M, Steiner D, Dey A. GSK-3 inactivation or depletion promotes β-cell replication via down regulation of the CDK inhibitor, p27 (Kip1). Islets. 2011;3:21-34 pubmed
Mirando A, Maruyama T, Fu J, Yu H, Hsu W. ?-catenin/cyclin D1 mediated development of suture mesenchyme in calvarial morphogenesis. BMC Dev Biol. 2010;10:116 pubmed 出版商
Zhang Q, Gu J, Li L, Liu J, Luo B, Cheung H, et al. Control of cyclin D1 and breast tumorigenesis by the EglN2 prolyl hydroxylase. Cancer Cell. 2009;16:413-24 pubmed 出版商
Rankin M, Kushner J. Adaptive beta-cell proliferation is severely restricted with advanced age. Diabetes. 2009;58:1365-72 pubmed 出版商
Zheng Y, Bie W, Yang R, Perekatt A, Poole A, Tyner A. Functions of p21 and p27 in the regenerating epithelial linings of the mouse small and large intestine. Cancer Biol Ther. 2008;7:873-9 pubmed
Rubio D, Garcia S, Paz M, de la Cueva T, Lopez Fernandez L, Lloyd A, et al. Molecular characterization of spontaneous mesenchymal stem cell transformation. PLoS ONE. 2008;3:e1398 pubmed 出版商
Glickstein S, Moore H, Slowinska B, Racchumi J, Suh M, Chuhma N, et al. Selective cortical interneuron and GABA deficits in cyclin D2-null mice. Development. 2007;134:4083-93 pubmed
Andreu Vieyra C, Chen R, Matzuk M. Effects of granulosa cell-specific deletion of Rb in Inha-alpha null female mice. Endocrinology. 2007;148:3837-49 pubmed
Pogoriler J, Millen K, Utset M, Du W. Loss of cyclin D1 impairs cerebellar development and suppresses medulloblastoma formation. Development. 2006;133:3929-37 pubmed
Malik A, Afaq F, Sarfaraz S, Adhami V, Syed D, Mukhtar H. Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer. Proc Natl Acad Sci U S A. 2005;102:14813-8 pubmed
Chen B, Pollard J. Cyclin D2 compensates for the loss of cyclin D1 in estrogen-induced mouse uterine epithelial cell proliferation. Mol Endocrinol. 2003;17:1368-81 pubmed
Gupta S, Afaq F, Mukhtar H. Involvement of nuclear factor-kappa B, Bax and Bcl-2 in induction of cell cycle arrest and apoptosis by apigenin in human prostate carcinoma cells. Oncogene. 2002;21:3727-38 pubmed
Clark W, Black E, MacLaren A, Kruse U, LaThangue N, Vogt P, et al. v-Jun overrides the mitogen dependence of S-phase entry by deregulating retinoblastoma protein phosphorylation and E2F-pocket protein interactions as a consequence of enhanced cyclin E-cdk2 catalytic activity. Mol Cell Biol. 2000;20:2529-42 pubmed
Tsutsui T, Hesabi B, Moons D, Pandolfi P, Hansel K, Koff A, et al. Targeted disruption of CDK4 delays cell cycle entry with enhanced p27(Kip1) activity. Mol Cell Biol. 1999;19:7011-9 pubmed
产品信息
产品类型 :
抗体
产品名称 :
细胞周期蛋白D2单克隆抗体(DCS-3.1)
目录# :
MA5-12712
规格 :
500微升
价格 :
美国344.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL, Western Blot: Assay-dependent
物种 :
人类, 小鼠, 大鼠
克隆 :
DCS-3.1
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Cyclin D2 is a G1 cyclin required for G1 phase progression and is a strong candidate for a proto-oncogene. Cyclin D2 can phosphorylate pRB when associated with cdk 4 and / or cdk 6.
免疫原 :
纯化人类重组全长细胞周期蛋白D2蛋白
格式 :
液体
应用w/稀释 :
Flow Cytometry: Assay-dependent, Immunocytochemistry: Assay-dependent, Immunoprecipitation: 2 µg/mL, Western Blot: Assay-dependent
别名 :
2600016F06Rik; AI256817; BF642806; C86853; CCND2; cD2; cyclin D2; Cyl-2; G1/S-specific cyclin-D2; KIAK0002; MGC102758; MPPH3; Vin1; Vin-1; Vin-1 proto-oncogene
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国