产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
RAB9单克隆抗体(Mab9)
目录 :
MA3-067
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
Mab9
反应物种 :
中国人仓鼠, 人类, 大鼠, 犬, 牛
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫沉淀, 流式细胞仪
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 人类; 1:1000; 图 4
Clifford R, Maryon E, Kaplan J. Dynamic internalization and recycling of a metal ion transporter: Cu homeostasis and CTR1, the human Cu⁺ uptake system. J Cell Sci. 2016;129:1711-21 pubmed 出版商
  • 免疫组化; 人类; 1:50
  • 免疫印迹; 人类; 1:500
Thoeni C, Vogel G, Tancevski I, Geley S, Lechner S, Pfaller K, et al. Microvillus inclusion disease: loss of Myosin vb disrupts intracellular traffic and cell polarity. Traffic. 2014;15:22-42 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Vogt D, Camus G, Herker E, Webster B, Tsou C, Greene W, et al. Lipid droplet-binding protein TIP47 regulates hepatitis C Virus RNA replication through interaction with the viral NS5A protein. PLoS Pathog. 2013;9:e1003302 pubmed 出版商
  • 免疫组化; 人类; 1:200
  • 免疫印迹; 人类; 1:250
Uemura N, Nakanishi Y, Kato H, Nagino M, Hirohashi S, Kondo T. Antibody-based proteomics for esophageal cancer: Identification of proteins in the nuclear factor-kappaB pathway and mitotic checkpoint. Cancer Sci. 2009;100:1612-22 pubmed 出版商
  • 免疫组化; 人类; 1:200
Cirillo C, Sarnelli G, Esposito G, Grosso M, Petruzzelli R, Izzo P, et al. Increased mucosal nitric oxide production in ulcerative colitis is mediated in part by the enteroglial-derived S100B protein. Neurogastroenterol Motil. 2009;21:1209-e112 pubmed 出版商
  • 免疫组化; 人类; 1:200
Trere D, Brighenti E, Donati G, Ceccarelli C, Santini D, Taffurelli M, et al. High prevalence of retinoblastoma protein loss in triple-negative breast cancers and its association with a good prognosis in patients treated with adjuvant chemotherapy. Ann Oncol. 2009;20:1818-23 pubmed 出版商
  • 流式细胞仪; 人类; 1:200
Vernet E, Lundberg E, Friedman M, Rigamonti N, Klausing S, Nygren P, et al. Affibody-mediated retention of the epidermal growth factor receptor in the secretory compartments leads to inhibition of phosphorylation in the kinase domain. N Biotechnol. 2009;25:417-23 pubmed 出版商
  • 免疫细胞化学; 人类; 1:30
Rögelsperger O, Ekmekcioglu C, Jager W, Klimpfinger M, Konigsberg R, Krenbek D, et al. Coexpression of the melatonin receptor 1 and nestin in human breast cancer specimens. J Pineal Res. 2009;46:422-32 pubmed 出版商
  • 免疫印迹; 人类
Belov G, Habbersett C, Franco D, Ehrenfeld E. Activation of cellular Arf GTPases by poliovirus protein 3CD correlates with virus replication. J Virol. 2007;81:9259-67 pubmed
Kane M, Diamonstein C, Hauser N, Deeken J, Niederhuber J, Vilboux T. Endosomal trafficking defects in patient cells with KIAA1109 biallelic variants. Genes Dis. 2019;6:56-67 pubmed 出版商
Lambert L, Dubayle D, Fafouri A, Herzog E, Csaba Z, Dournaud P, et al. Endocytosis of Activated Muscarinic m2 Receptor (m2R) in Live Mouse Hippocampal Neurons Occurs via a Clathrin-Dependent Pathway. Front Cell Neurosci. 2018;12:450 pubmed 出版商
Cheng X, Xie Y, Zhou B, Huang N, Farfel Becker T, Sheng Z. Characterization of LAMP1-labeled nondegradative lysosomal and endocytic compartments in neurons. J Cell Biol. 2018;217:3127-3139 pubmed 出版商
Janickova H, Prado V, Prado M, El Mestikawy S, Bernard V. Vesicular acetylcholine transporter (VAChT) over-expression induces major modifications of striatal cholinergic interneuron morphology and function. J Neurochem. 2017;142:857-875 pubmed 出版商
Zhang X, Jiang S, Mitok K, Li L, Attie A, Martin T. BAIAP3, a C2 domain-containing Munc13 protein, controls the fate of dense-core vesicles in neuroendocrine cells. J Cell Biol. 2017;216:2151-2166 pubmed 出版商
Ivanov A, Nusrat A, Parkos C. Endocytosis of epithelial apical junctional proteins by a clathrin-mediated pathway into a unique storage compartment. Mol Biol Cell. 2004;15:176-88 pubmed
Cheng F, Mani K, van den Born J, Ding K, Belting M, Fransson L. Nitric oxide-dependent processing of heparan sulfate in recycling S-nitrosylated glypican-1 takes place in caveolin-1-containing endosomes. J Biol Chem. 2002;277:44431-9 pubmed
Lorenzo M, Jung J, Ploegh H. Kaposi's sarcoma-associated herpesvirus K3 utilizes the ubiquitin-proteasome system in routing class major histocompatibility complexes to late endocytic compartments. J Virol. 2002;76:5522-31 pubmed
Soldati T, Riederer M, Pfeffer S. Rab GDI: a solubilizing and recycling factor for rab9 protein. Mol Biol Cell. 1993;4:425-34 pubmed
Shapiro A, Pfeffer S. Quantitative analysis of the interactions between prenyl Rab9, GDP dissociation inhibitor-alpha, and guanine nucleotides. J Biol Chem. 1995;270:11085-90 pubmed
图像
图像 1 :
赛默飞世尔 MA3-067 图像 1
Immunofluorescent analysis of RAB9 using RAB9 Monoclonal Antibody (Mab9) (Product# MA3-067 ) shows staining in A2058 Cells. RAB9 (green), F-Actin staining with Phalloidin (red) and nuclei with DAPI (blue) is shown. Cells were grown on chamber slides and fixed with formaldehyde prior to staining. Cells were probed without (control) or with an antibody recognizing RAB9 (Product# MA3-067 ) at a dilution of 1:100 over night at 4 ?C, washed with PBS and incubated with a DyLight-488 conjugated secondary antibody (Product# 35552 for GAR, Product# 35503 for GAM). Images were taken at 60X magnification.
产品信息
产品类型 :
抗体
产品名称 :
RAB9单克隆抗体(Mab9)
目录# :
MA3-067
规格 :
100微升
价格 :
美国425.00
克隆性 :
单克隆
宿主 :
小鼠
反应物种 :
Bovine, Canine, Hamster, Human, Non-human primate, Rat
应用 :
Immunocytochemistry: 1:200-1:500, Immunohistochemistry: 1:20, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000-1:5,000
物种 :
Bovine, Canine, Hamster, Human, Non-human primate, Rat
克隆 :
Mab9
抗体亚型 :
IgG1
储存 :
-20° C, 避免反复冷冻/解冻
描述 :
Rab proteins are a family of Ras-like GTPases involved in intracellular compartment protein transport. Different members of the 40+ member rab family are responsible for docking and fusion of transport vesicles between different compartments within the cell. Rab 9 is required for trafficking mannose 6-phosphate receptor between the late endosome to trans-Golgi network (TGN). By facilitating receptor transport, rab 9 enables cells to efficiently recycle important cellular trafficking components. It is functionally necessary for rab 9, like other rab family members, to be prenylated by two 20-carbon geranylgeranyl groups at the C-terminus. Most prenylated rab 9 is membrane bound, however, 10-20% of the cellular pool of rab 9 is bound to GDP dissociation inhibitor-alpha (GDI-alpha) in the cytosol. GDI recycles prenylated, GDP bound rab 9 from their fusion targets back to their membranes of origin.
免疫原 :
Recombinant canine rab 9a.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:200-1:500, Immunohistochemistry: 1:20, Immunomicroscopy: Assay-dependent, Immunoprecipitation: Assay-dependent, Western Blot: 1:1,000-1:5,000
别名 :
2410064E05Rik; AI195561; rab9; rab9 GTP-binding protein; RAB9, member RAS oncogene family; Rab9a; rab-9A; RAB9A, member RAS oncogene family; RAB9-like protein; ras-related protein Rab-9A; Sid 99; Sid6061p; Sid99
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国