产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
钙联接蛋白单克隆抗体(AF18), Alexa Fluor系列荧光染料488
目录 :
MA3-027-A488
规格 :
50微升
价格 :
美国325.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
AF18
反应物种 :
人类, 小鼠
应用 :
免疫细胞化学
更多信息或购买 :
文章摘录数: 3
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产品信息
产品类型 :
抗体
产品名称 :
钙联接蛋白单克隆抗体(AF18), Alexa Fluor系列荧光染料488
目录# :
MA3-027-A488
规格 :
50微升
价格 :
美国325.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1-10 µg/mL
物种 :
人类, 小鼠
克隆 :
AF18
抗体亚型 :
IgG1
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Calnexin, also referred to as IP90, p88 and p90, is an approximately 90 kDa integral membrane protein of the endoplasmic reticulum (ER). Many resident ER proteins act as molecular chaperones and participate in the proper folding of polypeptides and their assembly into multisubunit proteins. Studies indicate that calnexin associates with the major histocompatibility complex (MHC) class I heavy chains, partial complexes of the T cell receptor and B cell membrane immunoglobulin, but not with completed receptor complexes. It has been shown that calnexin is a chaperone that retains incompletely or improperly folded proteins in the ER. The sequence Lys-Asp-Glu-Leu (KDEL) or a closely related sequence, is present at the carboxy-terminus of soluble ER resident proteins such as GRP78 and GRP94 and protein disulfide isomerase. Integral membrane ER resident proteins, like calnexin, often lack this KDEL sequence but contain positively charged cytosolic residues that ensure ER retention. Calnexin contains a large ER luminal domain (461 amino acids), a transmembrane segment (22 amino acids), and a cytoplasmic tail (89 amino acids).
免疫原 :
Focus human hepatoma cell lysate
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1-10 µg/mL
别名 :
1110069N15Rik; AI988026; calmegin; calnexin; canx; canx-a; canx-b; clgn; clnx; cnx; D11Ertd153e; FLJ26570; hypothetical protein; IP90; Major histocompatibility complex class I antigen-binding protein p88; p88; P90; PP90; pp90 precursor
更多信息或购买 :
公司信息
赛默飞世尔