产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
ITGB1单克隆抗体(TS2/16)
目录 :
MA2910
规格 :
200微克
价格 :
美国400.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
TS2/16
反应物种 :
人类, 小鼠, 家羊
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 家羊; 图 2b
Hunka J, Riley J, Debes G. Approaches to overcome flow cytometry limitations in the analysis of cells from veterinary relevant species. BMC Vet Res. 2020;16:83 pubmed 出版商
  • 抑制或激活实验; 人类; 20 ug/ml; 图 1
Høye A, Couchman J, Wewer U, Yoneda A. The Phosphorylation and Distribution of Cortactin Downstream of Integrin α9β1 Affects Cancer Cell Behaviour. Sci Rep. 2016;6:28529 pubmed 出版商
  • 流式细胞仪; 人类; 图 2a
Jürets A, Le Bras M, Staffler G, Stein G, Leitner L, Neuhofer A, et al. Inhibition of Cellular Adhesion by Immunological Targeting of Osteopontin Neoepitopes Generated through Matrix Metalloproteinase and Thrombin Cleavage. PLoS ONE. 2016;11:e0148333 pubmed 出版商
  • 免疫细胞化学; 人类
  • 免疫印迹; 人类
Beaty B, Sharma V, Bravo Cordero J, Simpson M, Eddy R, Koleske A, et al. ?1 integrin regulates Arg to promote invadopodial maturation and matrix degradation. Mol Biol Cell. 2013;24:1661-75, S1-11 pubmed 出版商
  • 流式细胞仪; 人类
  • 免疫印迹; 人类
Binsky I, Lantner F, Grabovsky V, Harpaz N, Shvidel L, Berrebi A, et al. TAp63 regulates VLA-4 expression and chronic lymphocytic leukemia cell migration to the bone marrow in a CD74-dependent manner. J Immunol. 2010;184:4761-9 pubmed 出版商
  • 抑制或激活实验; 人类
Tanaka M, Abe T, Hara Y. Roles of focal adhesions and fibronectin-mediated cohesion in proliferation of confluent fibroblasts. J Cell Physiol. 2009;219:194-201 pubmed 出版商
  • 免疫组化; 人类
Wijnhoven J, Hafmans T, Dekhuijzen P. Distribution of costameric proteins in the diaphragm of patients with chronic obstructive pulmonary disease. Respiration. 2006;73:529-37 pubmed
  • 抑制或激活实验; 小鼠
Jones N, Peak J, Brader S, Eccles S, Katan M. PLCgamma1 is essential for early events in integrin signalling required for cell motility. J Cell Sci. 2005;118:2695-706 pubmed
Erami Z, Heitz S, Bresnick A, Backer J. PI3Kβ links integrin activation and PI(3,4)P2 production during invadopodial maturation. Mol Biol Cell. 2019;30:2367-2376 pubmed 出版商
García Diaz B, Bachelin C, Coulpier F, Gerschenfeld G, Deboux C, Zujovic V, et al. Blood vessels guide Schwann cell migration in the adult demyelinated CNS through Eph/ephrin signaling. Acta Neuropathol. 2019;: pubmed 出版商
Myllymäki S, Kämäräinen U, Liu X, Cruz S, Miettinen S, Vuorela M, et al. Assembly of the β4-Integrin Interactome Based on Proximal Biotinylation in the Presence and Absence of Heterodimerization. Mol Cell Proteomics. 2019;18:277-293 pubmed 出版商
Machado Pineda Y, Cardeñes B, Reyes R, López Martín S, Toribio V, Sánchez Organero P, et al. CD9 Controls Integrin α5β1-Mediated Cell Adhesion by Modulating Its Association With the Metalloproteinase ADAM17. Front Immunol. 2018;9:2474 pubmed 出版商
Alejo A, Matamoros T, Guerra M, Andres G. A Proteomic Atlas of the African Swine Fever Virus Particle. J Virol. 2018;92: pubmed 出版商
Yoneyama Y, Lanzerstorfer P, Niwa H, Umehara T, Shibano T, Yokoyama S, et al. IRS-1 acts as an endocytic regulator of IGF-I receptor to facilitate sustained IGF signaling. elife. 2018;7: pubmed 出版商
Parikh Z, Tripathi A, Pillai P. Differential Regulation of MeCP2 Phosphorylation by Laminin in Oligodendrocytes. J Mol Neurosci. 2017;62:309-317 pubmed 出版商
Mattila J, Beaino W, Maiello P, Coleman M, White A, Scanga C, et al. Positron Emission Tomography Imaging of Macaques with Tuberculosis Identifies Temporal Changes in Granuloma Glucose Metabolism and Integrin ?4?1-Expressing Immune Cells. J Immunol. 2017;199:806-815 pubmed 出版商
Starchenko A, Graves Deal R, Yang Y, Li C, Zent R, Singh B, et al. Clustering of integrin α5 at the lateral membrane restores epithelial polarity in invasive colorectal cancer cells. Mol Biol Cell. 2017;28:1288-1300 pubmed 出版商
Michishita M, Ezaki S, Ogihara K, Naya Y, Azakami D, Nakagawa T, et al. Identification of tumor-initiating cells in a canine hepatocellular carcinoma cell line. Res Vet Sci. 2014;96:315-22 pubmed 出版商
Kokkoli E, Ochsenhirt S, Tirrell M. Collective and single-molecule interactions of alpha5beta1 integrins. Langmuir. 2004;20:2397-404 pubmed
Beauvais D, Rapraeger A. Syndecan-1-mediated cell spreading requires signaling by alphavbeta3 integrins in human breast carcinoma cells. Exp Cell Res. 2003;286:219-32 pubmed
Malawista S, De Boisfleury Chevance A, Brown E, Boxer L, Law S. Chemotaxis of non-compressed blood polymorphonuclear leukocytes from an adolescent with severe leukocyte adhesion deficiency. Am J Hematol. 2003;73:115-20 pubmed
Baba T, Udaka K, Terada N, Ueda H, Fujii Y, Ohno S, et al. Actin-rich spherical extrusion induced in okadaic acid-treated K562 cells by crosslinking of membrane microdomains. J Histochem Cytochem. 2003;51:245-52 pubmed
Liu D, Aguirre Ghiso J, Estrada Y, Ossowski L. EGFR is a transducer of the urokinase receptor initiated signal that is required for in vivo growth of a human carcinoma. Cancer Cell. 2002;1:445-57 pubmed
Shen W, Bendall L, Gottlieb D, Bradstock K. The chemokine receptor CXCR4 enhances integrin-mediated in vitro adhesion and facilitates engraftment of leukemic precursor-B cells in the bone marrow. Exp Hematol. 2001;29:1439-47 pubmed
Abe T, Abe Y, Aida Y, Hara Y, Maeda K. Extracellular matrix regulates induction of alkaline phosphatase expression by ascorbic acid in human fibroblasts. J Cell Physiol. 2001;189:144-51 pubmed
Dillo A, Ochsenhirt S, McCarthy J, Fields G, Tirrell M. Adhesion of alpha5beta1 receptors to biomimetic substrates constructed from peptide amphiphiles. Biomaterials. 2001;22:1493-505 pubmed
Schulte R, Grassl G, Preger S, Fessele S, Jacobi C, Schaller M, et al. Yersinia enterocolitica invasin protein triggers IL-8 production in epithelial cells via activation of Rel p65-p65 homodimers. FASEB J. 2000;14:1471-84 pubmed
Aguirre Ghiso J, Kovalski K, Ossowski L. Tumor dormancy induced by downregulation of urokinase receptor in human carcinoma involves integrin and MAPK signaling. J Cell Biol. 1999;147:89-104 pubmed
Stanton K, Frewin M, Gudewicz P. Heterologous desensitization of IL-8-mediated chemotaxis in human neutrophils by a cell-binding fragment of fibronectin. J Leukoc Biol. 1999;65:515-22 pubmed
Wei Y, Yang X, Liu Q, Wilkins J, Chapman H. A role for caveolin and the urokinase receptor in integrin-mediated adhesion and signaling. J Cell Biol. 1999;144:1285-94 pubmed
Brayton J, Qing Z, Hart M, VanGilder J, Fabry Z. Influence of adhesion molecule expression by human brain microvessel endothelium on cancer cell adhesion. J Neuroimmunol. 1998;89:104-12 pubmed
Arroyo A, Garcia Pardo A, Sanchez Madrid F. A high affinity conformational state on VLA integrin heterodimers induced by an anti-beta 1 chain monoclonal antibody. J Biol Chem. 1993;268:9863-8 pubmed
Chan B, Elices M, Murphy E, Hemler M. Adhesion to vascular cell adhesion molecule 1 and fibronectin. Comparison of alpha 4 beta 1 (VLA-4) and alpha 4 beta 7 on the human B cell line JY. J Biol Chem. 1992;267:8366-70 pubmed
产品信息
产品类型 :
抗体
产品名称 :
ITGB1单克隆抗体(TS2/16)
目录# :
MA2910
规格 :
200微克
价格 :
美国400.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
小鼠
反应物种 :
人类
应用 :
Flow Cytometry: 0.5 µg/test
物种 :
人类
克隆 :
TS2/16
抗体亚型 :
IgG1
储存 :
-20°C
描述 :
ITGB1 (Integrin Subunit Beta 1, beta1 integrin subunit, GPIIa, CD29) is a 110 kDa cell surface glycoprotein that is widely expressed by a variety of cells including all leucocytes. ITGB1 forms non-covalently linked heterodimers with at least 6 different alpha chains (alpha1-alpha6, CDa-f) determining the binding properties of beta1 (VLA) integrins. ITGB1 is a cell adhesion molecule appearing on platelets, as the common Beta subunit of the very late activation antigen (VLA), and as a component of various protein complexes binding to extracellular matrix proteins. Decreased expression of ITGB1 correlates with acquiring multidrug resistance of tumor cells in the presence of anti-tumor drug. ITGB1 is up-regulated in leukocytes during emigration and extravascular migration and appear to be critically involved in regulating the immune cell trafficking from blood to tissue. Further, ITGB1 also regulates tissue damage and disease symptoms related to inflammatory bowel disease. Through an ITGB1-dependent mechanism, fibronectin and type I collagen enhance cytokine secretion of human airway smooth muscle in response to IL-1beta. More than 8 beta subunits with numerous splice variant isoforms have been identified in mammals. There are two major forms of integrin beta1: beta1A and beta1D, which differ in 13 amino acids. The distribution pattern in adult tissues for integrin beta types are mutually exclusive. Beta1A is present in all tissues, except cardiac and skeletal muscle which express the beta1D variant.
免疫原 :
Human Beta1 Integrin, the Beta1 chain of the Beta1 integrin heterodimer (CD29)
格式 :
液体
应用w/稀释 :
Flow Cytometry: 0.5 µg/test
别名 :
4633401G24Rik; AA409975; AA960159; Beta OL; beta oligodendroglia; CD29; CSAT antigen; ENSMUSG00000051907; Fibronectin receptor subunit beta; FNRB; Glycoprotein IIa; Gm9863; gpIIa; integrin beta 1; integrin beta 1 (fibronectin receptor beta); integrin beta 1A precursor; Integrin beta1; integrin beta-1; integrin beta-1 subunit; integrin beta1D; integrin precursor; integrin subunit beta 1; integrin VLA-4 beta subunit; integrin VLA-4 subunit beta; integrin, beta 1; integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12); ITBG1D; ITGB1; JG22 antigen; MDF2; MSK12; RGD-receptor; very late activation protein, beta polypeptide; VLA-4 subunit beta; VLAB; VLA-BETA
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国