产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
IL-10单克隆抗体(JES3-12G8)
目录 :
MA1-82664
规格 :
1毫升
价格 :
美国449.00
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
JES3-12G8
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 流式细胞仪, 免疫组化-石蜡切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:100; 图 4
Roth S, Spalinger M, Gottier C, Biedermann L, Zeitz J, Lang S, et al. Bilberry-Derived Anthocyanins Modulate Cytokine Expression in the Intestine of Patients with Ulcerative Colitis. PLoS ONE. 2016;11:e0154817 pubmed 出版商
  • 免疫组化; 人类; 1:100
Bloch O, Crane C, Kaur R, Safaee M, Rutkowski M, Parsa A. Gliomas promote immunosuppression through induction of B7-H1 expression in tumor-associated macrophages. Clin Cancer Res. 2013;19:3165-75 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 表 1
Meloni F, Cascina A, Paschetto E, Marone Bianco A, Morosini M, Pellegrini C, et al. Monocyte chemoattractant protein-1 levels in bronchoalveolar lavage fluid of lung-transplanted patients treated with tacrolimus as rescue treatment for refractory acute rejection. Transplant Proc. 2003;35:1523-6 pubmed
  • 酶联免疫吸附测定; 人类; 图 1
Gotlieb W, Abrams J, Watson J, Velu T, Berek J, Martínez Maza O. Presence of interleukin 10 (IL-10) in the ascites of patients with ovarian and other intra-abdominal cancers. Cytokine. 1992;4:385-90 pubmed
Hong N, Ku S, Yuk K, Johnston T, Ji G, Park M. Production of biologically active human interleukin-10 by Bifidobacterium bifidum BGN4. Microb Cell Fact. 2021;20:16 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
IL-10单克隆抗体(JES3-12G8)
目录# :
MA1-82664
规格 :
1毫升
价格 :
美国449.00
克隆性 :
单克隆
纯度 :
蛋白质G
宿主 :
大鼠
反应物种 :
人类
应用 :
ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1/50 - 1/100, Western Blot: 1/50-1/250
物种 :
人类
克隆 :
JES3-12G8
抗体亚型 :
IgG2a
储存 :
4° C, 不冻结
描述 :
IL-10 encodes a protein that acts as a cytokine and is primarily produced by monocytes, with some production by lymphocytes. This cytokine has various effects on immunoregulation and inflammation, including down-regulating the expression of Th1 cytokines, MHC class II Ags, and costimulatory molecules on macrophages. It also enhances B cell survival, proliferation, and antibody production. Additionally, IL-10 can block NF-kappa B activity and is involved in the regulation of the JAK-STAT signaling pathway. Knockout studies in mice have suggested that this cytokine is an essential immunoregulator in the intestinal tract. Mutations in this gene have been associated with an increased susceptibility to HIV-1 infection and rheumatoid arthritis. Diseases associated with IL10 include Graft-Versus-Host Disease and Human Immunodeficiency Virus Type 1.
免疫原 :
Human IL-10 expressed by COS cells.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Flow Cytometry: Assay-dependent, Immunohistochemistry (Paraffin): 1/50 - 1/100, Western Blot: 1/50-1/250
别名 :
CSIF; cytokine; Cytokine synthesis inhibitory factor; GVHDS; H-IL-10; il 10; IL10; IL-10; IL-10 precursor; IL10A; IL10X; ILN; Interleukin; interleukin 10; Interleukin10; interleukin-10; MGC126450; MGC126451; RP11-262N9.1; T-cell growth inhibitory factor; TGIF
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国