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抗体

弹性蛋白单克隆抗体(VI-RE/1)

MA1-19319

100微克

美国399

单克隆

小鼠

未共轭

VI-RE/1

人类, 小鼠

免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪

弹性蛋白单克隆抗体(VI-RE/1)

MA1-19319

100微克

美国399

单克隆

蛋白质A

小鼠

人类, 小鼠

ELISA: Assay Dependent, Flow Cytometry: 1-10 µg/mL, Immunocytochemistry: Assay Dependent, Western Blot: 1:2000

人类, 小鼠

VI-RE/1

IgG1

4° C, 不冻结

Vimentin is a developmentally regulated intermediate filament protein (IFP) found in cells of mesenchymal origin. It is believed to be involved with the intracellular transport of proteins between the nucleus and plasma membrane. Unlike other IFP proteins, vimentin is expressed, along with desmin, during the early stages of cellular development. During the development process, vimentin is exchanged for new, tissue-specific IFPs. Vimentin has been implicated to be involved in the rate of steroid synthesis via its role as a storage network for steroidogenic cholesterol containing lipid droplets. Vimentin phosphorylation by a protein kinase causes the breakdown of intermediate filaments and activation of an ATP and myosin light chain dependent contractile event. This results in cytoskeletal changes that facilitate the interaction of the lipid droplets within mitochondria, and subsequent transport of cholesterol to the organelles leading to an increase in steroid synthesis.

Bacterially expressed full-length human vimentin

液体

ELISA: Assay Dependent, Flow Cytometry: 1-10 µg/mL, Immunocytochemistry: Assay Dependent, Western Blot: 1:2000

cb28; CTRCT30; epididymis luminal protein 113; FLJ36605; HEL113; intermediate filament; intermediate filament protein; RP11-124N14.1; similar to vimentin; Vim; VIME; Vimentin