产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
ELISA/assay
产品名称 :
胰岛素样生长因子1受体人类酶联免疫吸附试剂盒
目录 :
EHIGF1R
规格 :
96试验
价格 :
459.00美元
更多信息或购买 :
产品信息
产品类型 :
酶联免疫吸附测定
目录号 :
EHIGF1R
类别 :
酶联免疫吸附试剂盒
靶标 :
胰岛素样生长因子1受体(CD221)
产品名称 :
胰岛素样生长因子1受体人类酶联免疫吸附试剂盒
描述 :
IGF1R, also known as Insulin-like Growth Factor 1 (IGF-1) Receptor, is a receptor tyrosine kinase activated by IGF-1 and IGF-2. IGFR has been implicated in a variety of cancers. The protein is a tetramer consisting of two alpha, and two beta subunits. The alpha-subunits binds to insulin growth factor 1 with higher affinity than to insulin growth factor 2. Binding results in a conformational change, followed by autophosphorylation of IGF-1R at positions 1134, 1135, 1136. The activated IGF-1R in turn, causes phosphorylation of substrate proteins, followed by sequential activation of RAS, RAF, and mitogen-activated protein kinase isoforms ERK, p38, and JNK, leading to the transcription of genes that drive proliferation.
同义词 :
A330103N21Rik; CD221; CD221 antigen; D930020L01; hyft; IGF 1 receptor; IGF 1R; IGF1R; IGF-1R; IGF-I receptor; IGFIR; IGFIRC; IGFR; Igfr1; insulin like growth factor 1 receptor; Insulin like growth factor 1 receptor precursor; insulin-like growth factor 1 receptor; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; Insulin-like growth factor I receptor; JTK13; line 186; soluble IGF1R variant 1; soluble IGF1R variant 2
价格(美元) :
459.00美元
规格 :
96试验
物种活性 :
人类
应用 :
酶联免疫吸附测定
储存 :
2-8°C
检测范围 :
8.23-6000 pg/mL
样品类型 :
Plasma, 50 µL Serum, 50 µL Supernatant, 100 µL
Assay Length :
1小时20分钟
提示 :
This product is for research use only.
更多信息或购买 :
公司信息
赛默飞世尔