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ELISA/assay

人类BID酶联免疫吸附试剂盒

EH44RBX5

5 x 96试验

2236.50美元

EH44RBX5

酶联免疫吸附试剂盒

BID

人类BID酶联免疫吸附试剂盒

BID is a death agonist that heterodimerizes with either agonist BAX or antagonist BCL2. Bid is a member of the BCL-2 family of cell death regulators. BID is a mediator of mitochondrial damage induced by caspase-8 (CASP8); CASP8 cleaves this encoded protein, and the COOH-terminal part translocates to mitochondria where it triggers cytochrome c release. BID is also a pro-apoptotic member of the Bcl 2 family. BID usually exists in an inactive form in the cytosolic fraction of living cells and becomes cleaved and activated by caspase 8 in response to TNF alpha or Fas ligand. Once BID is cleaved, the C-terminal 15 kDa fragment of BID (p15) translocates onto mitochondria and is sufficient to trigger cytochrome c release, resulting in cell apoptosis. BID serves as a direct molecular link between caspase 8 activation and mitochondrial death machinery.

2700049M22Rik; AI875481; apoptic d; apoptic death agonist; apoptotic death agonist BID; AU022477; BH3 interacting domain death agonist; BH3-interacting domain death agonist; BH3-interacting domain death agonist p11; BH3-interacting domain death agonist p13; BH3-interacting domain death agonist p15; Bid; BID isoform ES(1b); BID isoform L(2); BID isoform Si6; desmocollin type 4; FP497; HGNC:1050; Human BID coding sequence; MGC15319; MGC42355; OTTHUMP00000196197; p11 BID; p13 BID; p15 BID; p22 BID

2236.50美元

5 x 96试验

人类

酶联免疫吸附测定

2-8°C

3.2-300 ng/mL

Plasma, 50 µL Serum, 50 µL Supernatant, 50 µL

1小时20分钟

This product is for research use only.