产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
ELISA/assay
产品名称 :
人类雄激素受体酶联免疫吸附试剂盒
目录 :
EEL028
规格 :
96试验
价格 :
618.80美元
更多信息或购买 :
产品信息
产品类型 :
酶联免疫吸附测定
目录号 :
EEL028
类别 :
酶联免疫吸附试剂盒
靶标 :
雄激素受体
产品名称 :
人类雄激素受体酶联免疫吸附试剂盒
描述 :
The androgen receptor (AR) is a member of the steroid-hormone receptor superfamily of nuclear receptors. The receptor is more than 90 kDa and has three major functional domains: the N-terminal domain, DNA-binding domain, and the androgen-binding domain. The androgen receptor is a ligand-activated transcription factor that binds active testosterone (T) and dihydrotestosterone (DHT). Upon binding the hormone ligand, the receptor dissociates from accessory proteins, translocates into the nucleus, dimerizes, and then stimulates transcription of androgen responsive genes. The AR signaling pathway plays a key role in development and function of male reproductive organs, including the prostate and epididymis. AR also plays a role in nonreproductive organs, such as muscle, hair follicles, and brain. Androgen Receptor is a phosphoprotein, and also regulates mitogen-activated protein kinase (MAP kinase). The inhibition of the MEK1/2 pathway correlates directly with a change in phosphorylation state of the androgen receptor. Abnormalities in the AR signaling pathway have been linked to a number of diseases, including prostate cancer, Kennedy's disease, and male infertility. Mutations in this gene are associated with complete androgen insensitivity (CAIS).
同义词 :
AIS; Andr; androgen nuclear receptor variant 2; androgen receptor; androgen receptor (Testicular feminization), same as Tfm; androgen receptor splice variant 4b; Ar; AR8; AR-A; AW320017; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; NR3C4; Nuclear receptor subfamily 3 group C member 4; RP11-383C12.1; SBMA; SMAX1; TFM; Variant AR45
价格(美元) :
618.80美元
规格 :
96试验
物种活性 :
人类
应用 :
酶联免疫吸附测定
储存 :
Refer to product documentation for component specific storage temperature.
检测范围 :
0.31-20 ng/mL
样品类型 :
血浆, 100微升血清, 100微升
Assay Length :
1小时20分钟
提示 :
This product is for research use only.
更多信息或购买 :
公司信息
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赛默飞世尔