产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
INSR甲单克隆抗体(83-14)
目录 :
AHR0221
规格 :
500微升
价格 :
美国466.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
83-14
反应物种 :
人类, 牛, pigs
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
产品信息
产品类型 :
抗体
产品名称 :
INSR甲单克隆抗体(83-14)
目录# :
AHR0221
规格 :
500微升
价格 :
美国466.00
克隆性 :
单克隆
纯度 :
蛋白质A
宿主 :
小鼠
反应物种 :
Bovine, Human, Ovine, Porcine
应用 :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunocytochemistry: 5 µg/mL, Immunoprecipitation: 2 µg / mg lysate, Inhibition Assays: Assay-dependent, Western Blot: 1 µg/mL
物种 :
Bovine, Human, Ovine, Porcine
克隆 :
83-14
抗体亚型 :
IgG2a, kappa
储存 :
4° C
描述 :
Biological actions of insulin and IGF-1 are mediated by their respective cell surface receptor tyrosine kinases that regulate multiple signaling pathways through activation of a series of phosphorylation cascades. The insulin receptor. Insulin/IGF-1 binding to the extracellular domain leads to autophosphorylation of downstream target proteins. These two receptors differ in sequence in regions that confer specificity for the designated ligand as well as in certain intracellular signaling domains, resulting in significant differences in the functional consequences of activation of each receptor. Defects in IR are the cause of various insulin resistance syndromes and IGF-1R defects may cause some forms of growth retardation. Both these signaling cascades are also important for the development of cancer.
免疫原 :
IM-9 lymphocytes followed by purified insulin receptor.
格式 :
液体
应用w/稀释 :
ELISA: Assay-dependent, Functional Assay: Assay-dependent, Immunocytochemistry: 5 µg/mL, Immunoprecipitation: 2 µg / mg lysate, Inhibition Assays: Assay-dependent, Western Blot: 1 µg/mL
别名 :
4932439J01Rik; CD220; CD220 beta; D630014A15Rik; DAF-2; HHF5; INSR; insulin receptor; insulin receptor (INSR); insulin receptor precursor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR alpha; IR beta; ir-A; IR-B
更多信息或购买 :
公司信息
赛默飞世尔