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抗体

MEK2重组兔单克隆抗体(B19H36L8)

700829

100微克

美国475.00

重组

domestic rabbit

未共轭

B19H36L8

免疫印迹, 免疫细胞化学

MEK2重组兔单克隆抗体(B19H36L8)

700829

100微克

美国475.00

重组单克隆

蛋白质A

兔

人类

Immunocytochemistry: 5 µg/mL, Western Blot: 1 µg/mL

人类

B19H36L8

IgG

短期存放在4°C。 为长期储存, 存放在-20°C, 避免反复冷冻/解冻

MEK1 (Mitogen activated protein kinase 1) catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in a Thr-Glu-Tyr sequence located in MAP kinases. MEK1 activates ERK1 and ERK2 MAP kinases. Mitogen activated protein kinase 2 (MEK2 or MAPKK2) is a member of a family of tyrosine/threonine protein kinases that activate the ERK1 and 2 and MAPK enzymes by phosphorylating both residues within the threonine/glutamate/tyrosine (TEY) motif in the activation loop. MEK1 and 2 are also activated by dual phosphorylation, which occurs on serine 218 and 222, in the activation loop of the MEK. Threonine 292 of MEK1 is phosphorylated by ERK 2, which serves as a negative feedback loop by suppressing activation of MEK1.

proprietary

液体

Immunocytochemistry: 5 µg/mL, Western Blot: 1 µg/mL

AA589381; CFC4; Dual specificity mitogen-activated protein kinase kinase 2; ERK activator kinase 2; ERK kinase 2; FLJ26075; MAP kinase kinase 2; MAP kinase/Erk kinase; MAP2K1; MAP2K2; MAPK; MAPK/ERK kinase 1; MAPK/ERK kinase 2; MAPKK 1; MAPKK 2; MAPKK2; MEK 1; MEK 2; MEK-1; Mek2; MEK-2; mitogen activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2; mitogen-activated protein kinase kinase 2, p45; MK2; MKK1; Mkk2; OTTHUMP00000165827; PRKMK1; PRKMK2; protein kinase, mitogen activated, kinase 2, p45