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抗体

CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), Alexa Fluor 700, eBioscience™

56-1379-42

100试验

美国329.00

单克隆

小鼠

AF700

4B4(4B4-1)

CD137 (4-1BB) Monoclonal Antibody (4B4 (4B4-1)), Alexa Fluor 700, eBioscience™

56-1379-42

100试验

美国329.00

单克隆

亲和色谱

小鼠

人类

Flow Cytometry: 5 µL (0.25 µg)/test

人类

4B4(4B4-1)

IgG1, kappa

4° C, store in dark, DO NOT FREEZE!

CD137, also known as TNFRSF9 or 4-1BB, is an inducible costimulatory molecule expressed mainly on activated T cells. Its ligand, known as 4-1BBL, is expressed on activated macrophages, mature B cells, hematopoietic stem cells, and myeloid progenitor cells. CD137 signaling leads to maintaining the survival of activated T cells and CD8+ memory T cells, and clonal expansion of T cells, but also to suppressing myelopoiesis and dendritic cell development. Triggered CD137 induces a cytokine release profile regulating peripheral monocyte survival. Soluble forms of CD137 may provide negative control mechanism for some immune responses.

液体

Flow Cytometry: 5 µL (0.25 µg)/test

4 1 BB; 41BB; 4-1BB; 4-1BB ligand receptor; A930040I11Rik; AA408498; AI325004; Cd137; CD137 antigen; CDw137; EGK_00183; homolog of mouse 4-1BB; ILA; induced by lymphocyte activation (ILA); interleukin-activated receptor, homolog of mouse Ly63; Ly63; receptor protein 4-1BB; s4 1 BB; s4 1BB; s41BB; sCD137; secreted CD137 antigen; soluble 4 1 BB; soluble 4 1BB; soluble 41BB; soluble CD137; T cell antigen ILA; T-cell antigen 4-1BB; T-cell antigen 4-1BB homolog; T-cell antigen ILA; TNF receptor superfamily member 9; TNFRSF9; Tumor necrosis factor receptor superfamily member 9; tumor necrosis factor receptor superfamily, member 9