产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
Vinculin Monoclonal Antibody (7F9), Alexa Fluor™ 488, eBioscience
目录 :
53-9777-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
7F9
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 5
参考文献
Jarosch S, K xf6 hlen J, Wagner S, D Ippolito E, Busch D. ChipCytometry for multiplexed detection of protein and mRNA markers on human FFPE tissue samples. STAR Protoc. 2022;3:101374 pubmed 出版商
Alshaabi H, Shannon N, Gravelle R, Milczarek S, Messier T, Cunniff B. Miro1-mediated mitochondrial positioning supports subcellular redox status. Redox Biol. 2021;38:101818 pubmed 出版商
Pavlovic N, Calitz C, Thanapirom K, Mazza G, Rombouts K, Gerwins P, et al. Inhibiting IRE1α-endonuclease activity decreases tumor burden in a mouse model for hepatocellular carcinoma. elife. 2020;9: pubmed 出版商
Kim Y, Choi J, Yang M, Hong S, Lee C, Kubota Y, et al. A MST1-FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis. Nat Commun. 2019;10:838 pubmed 出版商
Chang C, Lee H, Lee C. Substrate properties modulate cell membrane roughness by way of actin filaments. Sci Rep. 2017;7:9068 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
Vinculin Monoclonal Antibody (7F9), Alexa Fluor™ 488, eBioscience
目录# :
53-9777-82
规格 :
100微克
价格 :
美国309.00
克隆性 :
单克隆
纯度 :
亲和色谱
宿主 :
小鼠
反应物种 :
人类, 小鼠, 大鼠
应用 :
Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent
物种 :
人类, 小鼠, 大鼠
克隆 :
7F9
抗体亚型 :
IgG1, kappa
储存 :
4° C, store in dark, DO NOT FREEZE!
描述 :
Vinculin (VCL) is a cytoskeletal protein associated with cell-cell and cell-extracellular matrix adherens-type junctions. It functions as one of several interacting proteins involved in anchoring F-actin to the membrane. It has been shown that a sequence of molecular interactions might be involved in the transmembrane assembly of adhesion plaques. In the assembly of adhesion plaques, the beta subunit of integrin binds to talin. Talin binds to vinculin that interacts with alpha-actinin and possibly with itself. Since alpha-actinin binds to and cross-links actin filaments, vinculin represents a key element in the transmembrane linkage of the extracellular matrix to the cytoplasmic microfilament system. Mutations in the gene can result in cardiomyopathy dilated 1W or familial hypertrophic 15.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:25-1:100, Immunohistochemistry (Frozen): Assay-Dependent, Immunohistochemistry (Paraffin): Assay-Dependent
别名 :
9430097D22; AA571387; AI462105; AW545629; CMD1W; CMH15; epididymis luminal protein 114; HEL114; metavinculin; meta-vinculin; metavinculin {ECO:0000250; MV; MVCL; RP11-178G16.3; UniProtKB:P18206}; unnamed protein product; Vcl; vcl {ECO:0000250; VIN; vinc; vinc 1; VINC1; Vinculin; vinculin {ECO:0000250
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国