| 参考文献 |
|---|
Shimada H, Sato Y, Sasaki T, Shimozawa A, Imaizumi K, Shindo T, et al. A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer. Cell Rep Methods. 2022;2:100289 pubmed 出版商 |
Solomon S, Sampathkumar N, Carre I, Mondal M, Chennell G, Vernon A, et al. Heterozygous expression of the Alzheimer's disease-protective PLCγ2 P522R variant enhances Aβ clearance while preserving synapses. Cell Mol Life Sci. 2022;79:453 pubmed 出版商 |
Xu J, Huang L, Fang Z, Luo H, Chen Y, Li Y, et al. Spinal dI4 Interneuron Differentiation From Human Pluripotent Stem Cells. Front Mol Neurosci. 2022;15:845875 pubmed 出版商 |
Pardieck J, Harb M, Sakiyama Elbert S. A transgenic mouse embryonic stem cell line for puromycin selection of V0V interneurons from heterogenous induced cultures. Stem Cell Res Ther. 2022;13:131 pubmed 出版商 |
Niu F, Han P, Zhang J, She Y, Yang L, Yu J, et al. The m6A reader YTHDF2 is a negative regulator for dendrite development and maintenance of retinal ganglion cells. elife. 2022;11: pubmed 出版商 |
Tomasello D, Kim J, Khodour Y, McCammon J, Mitalipova M, Jaenisch R, et al. 16pdel lipid changes in iPSC-derived neurons and function of FAM57B in lipid metabolism and synaptogenesis. iScience. 2022;25:103551 pubmed 出版商 |
Iennaco R, Formenti G, Trovesi C, Rossi R, Zuccato C, Lischetti T, et al. The evolutionary history of the polyQ tract in huntingtin sheds light on its functional pro-neural activities. Cell Death Differ. 2022;: pubmed 出版商 |
Ao Z, Cai H, Wu Z, Krzesniak J, Tian C, Lai Y, et al. Human Spinal Organoid-on-a-Chip to Model Nociceptive Circuitry for Pain Therapeutics Discovery. Anal Chem. 2022;94:1365-1372 pubmed 出版商 |
Jarazo J, Barmpa K, Modamio J, Saraiva C, Sabat xe9 Soler S, Rosety I, et al. Parkinson's Disease Phenotypes in Patient Neuronal Cultures and Brain Organoids Improved by 2-Hydroxypropyl-β-Cyclodextrin Treatment. Mov Disord. 2022;37:80-94 pubmed 出版商 |
Kim S, Larrous F, Varet H, Legendre R, Feige L, Dumas G, et al. Early Transcriptional Changes in Rabies Virus-Infected Neurons and Their Impact on Neuronal Functions. Front Microbiol. 2021;12:730892 pubmed 出版商 |
Morozzi G, Rothen J, Toussaint G, de Lange K, Westritschnig K, Doelemeyer A, et al. STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia. iScience. 2021;24:103434 pubmed 出版商 |
Behesti H, Kocabas A, Buchholz D, Carroll T, Hatten M. Altered temporal sequence of transcriptional regulators in the generation of human cerebellar granule cells. elife. 2021;10: pubmed 出版商 |
Ramic M, Andrade N, Rybin M, Esanov R, Wahlestedt C, Benatar M, et al. Epigenetic Small Molecules Rescue Nucleocytoplasmic Transport and DNA Damage Phenotypes in C9ORF72 ALS/FTD. Brain Sci. 2021;11: pubmed 出版商 |
Conde Dusman M, Dey P, Elía Zudaire Ó, Rabaneda L, García Lira C, Grand T, et al. Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly. elife. 2021;10: pubmed 出版商 |
Lo T, Figueroa Romero C, Hur J, Pacut C, Stoll E, Spring C, et al. Extracellular Vesicles in Serum and Central Nervous System Tissues Contain microRNA Signatures in Sporadic Amyotrophic Lateral Sclerosis. Front Mol Neurosci. 2021;14:739016 pubmed 出版商 |
Li J, Lim R, Kaye J, Dardov V, Coyne A, Wu J, et al. An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients. iScience. 2021;24:103221 pubmed 出版商 |
Ordureau A, Kraus F, Zhang J, An H, Park S, Ahfeldt T, et al. Temporal proteomics during neurogenesis reveals large-scale proteome and organelle remodeling via selective autophagy. Mol Cell. 2021;81:5082-5098.e11 pubmed 出版商 |
Hau A, Mommaerts E, Laub V, M xfc ller T, Dittmar G, Schulte D. Transcriptional cooperation of PBX1 and PAX6 in adult neural progenitor cells. Sci Rep. 2021;11:21013 pubmed 出版商 |
Walter J, Bolognin S, Poovathingal S, Magni S, G xe9 rard D, Antony P, et al. The Parkinson's-disease-associated mutation LRRK2-G2019S alters dopaminergic differentiation dynamics via NR2F1. Cell Rep. 2021;37:109864 pubmed 出版商 |
Li J, Chen L, Li D, Lu M, Huang X, Han X, et al. Electroacupuncture Promotes the Survival of the Grafted Human MGE Neural Progenitors in Rats with Cerebral Ischemia by Promoting Angiogenesis and Inhibiting Inflammation. Neural Plast. 2021;2021:4894881 pubmed 出版商 |
Even A, Morelli G, Turchetto S, Shilian M, Bail R, Laguesse S, et al. ATP-citrate lyase promotes axonal transport across species. Nat Commun. 2021;12:5878 pubmed 出版商 |
Guttenplan K, Weigel M, Prakash P, Wijewardhane P, Hasel P, Rufen Blanchette U, et al. Neurotoxic reactive astrocytes induce cell death via saturated lipids. Nature. 2021;599:102-107 pubmed 出版商 |
Mora Jimenez L, Valencia M, Sanchez Carpintero R, T xf8 nnesen J, Fadila S, Rubinstein M, et al. Transfer of SCN1A to the brain of adolescent mouse model of Dravet syndrome improves epileptic, motor, and behavioral manifestations. Mol Ther Nucleic Acids. 2021;25:585-602 pubmed 出版商 |
Singh T, Jiao Y, Ferrando L, Yablonska S, Li F, Horoszko E, et al. Neuronal mitochondrial dysfunction in sporadic amyotrophic lateral sclerosis is developmentally regulated. Sci Rep. 2021;11:18916 pubmed 出版商 |
Harberts J, Siegmund M, Schnelle M, Zhang T, Lei Y, Yu L, et al. Robust neuronal differentiation of human iPSC-derived neural progenitor cells cultured on densely-spaced spiky silicon nanowire arrays. Sci Rep. 2021;11:18819 pubmed 出版商 |
Wind M, Tsakiridis A. In Vitro Generation of Posterior Motor Neurons from Human Pluripotent Stem Cells. Curr Protoc. 2021;1:e244 pubmed 出版商 |
Li L, Conradson D, Bharat V, Kim M, Hsieh C, Minhas P, et al. A mitochondrial membrane-bridging machinery mediates signal transduction of intramitochondrial oxidation. Nat Metab. 2021;3:1242-1258 pubmed 出版商 |
Hu D, Sun X, Magpusao A, Fedorov Y, Thompson M, Wang B, et al. Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease. Nat Commun. 2021;12:5305 pubmed 出版商 |
Feliciano C, Wu K, Watry H, Marley C, Ramadoss G, Ghanim H, et al. Allele-Specific Gene Editing Rescues Pathology in a Human Model of Charcot-Marie-Tooth Disease Type 2E. Front Cell Dev Biol. 2021;9:723023 pubmed 出版商 |
Ramakrishna S, Jhaveri V, Konings S, Nawalpuri B, Chakraborty S, Holst B, et al. APOE4 Affects Basal and NMDAR-Mediated Protein Synthesis in Neurons by Perturbing Calcium Homeostasis. J Neurosci. 2021;41:8686-8709 pubmed 出版商 |
Lagomarsino V, PEARSE R, Liu L, Hsieh Y, Fernandez M, Vinton E, et al. Stem cell-derived neurons reflect features of protein networks, neuropathology, and cognitive outcome of their aged human donors. Neuron. 2021;109:3402-3420.e9 pubmed 出版商 |
Garone M, Birsa N, Rosito M, Salaris F, Mochi M, de Turris V, et al. ALS-related FUS mutations alter axon growth in motoneurons and affect HuD/ELAVL4 and FMRP activity. Commun Biol. 2021;4:1025 pubmed 出版商 |
Bassil R, Shields K, Granger K, Zein I, Ng S, Chih B. Improved modeling of human AD with an automated culturing platform for iPSC neurons, astrocytes and microglia. Nat Commun. 2021;12:5220 pubmed 出版商 |
Pandya N, Wang C, Costa V, Lopatta P, Meier S, Zampeta F, et al. Secreted retrovirus-like GAG-domain-containing protein PEG10 is regulated by UBE3A and is involved in Angelman syndrome pathophysiology. Cell Rep Med. 2021;2:100360 pubmed 出版商 |
Lai X, Liu J, Zou Z, Wang Y, Wang Y, Liu X, et al. SOX10 ablation severely impairs the generation of postmigratory neural crest from human pluripotent stem cells. Cell Death Dis. 2021;12:814 pubmed 出版商 |
Laukkanen L, Diniz C, Foulquier S, Prickaerts J, Castr xe9 n E, Casarotto P. Facilitation of TRKB Activation by the Angiotensin II Receptor Type-2 (AT2R) Agonist C21. Pharmaceuticals (Basel). 2021;14: pubmed 出版商 |
Restan Perez M, Sharma R, Masri N, WILLERTH S. 3D Bioprinting Mesenchymal Stem Cell-Derived Neural Tissues Using a Fibrin-Based Bioink. Biomolecules. 2021;11: pubmed 出版商 |
Cheng C, Reis S, Adams E, Fass D, Angus S, Stuhlmiller T, et al. High-content image-based analysis and proteomic profiling identifies Tau phosphorylation inhibitors in a human iPSC-derived glutamatergic neuronal model of tauopathy. Sci Rep. 2021;11:17029 pubmed 出版商 |
Kang Y, Zhou Y, Li Y, Han Y, Xu J, Niu W, et al. A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies. Nat Neurosci. 2021;24:1377-1391 pubmed 出版商 |
Dias C, Nita E, Faktor J, Tynan A, Hernychova L, Vojtesek B, et al. CHIP-dependent regulation of the actin cytoskeleton is linked to neuronal cell membrane integrity. iScience. 2021;24:102878 pubmed 出版商 |
Arnst N, Belio Mairal P, García González L, Arnaud L, Greetham L, Nivet E, et al. Deficiency in MT5-MMP Supports Branching of Human iPSCs-Derived Neurons and Reduces Expression of GLAST/S100 in iPSCs-Derived Astrocytes. Cells. 2021;10: pubmed 出版商 |
Shaker M, Aguado J, Chaggar H, Wolvetang E. Klotho inhibits neuronal senescence in human brain organoids. NPJ Aging Mech Dis. 2021;7:18 pubmed 出版商 |
Prelli Bozzo C, Nchioua R, Volcic M, Koepke L, Krüger J, Schütz D, et al. IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro. Nat Commun. 2021;12:4584 pubmed 出版商 |
De Bacco F, Orzan F, Erriquez J, Casanova E, Barault L, Albano R, et al. ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma. Cell Rep. 2021;36:109455 pubmed 出版商 |
Bowles K, Silva M, Whitney K, Bertucci T, Berlind J, Lai J, et al. ELAVL4, splicing, and glutamatergic dysfunction precede neuron loss in MAPT mutation cerebral organoids. Cell. 2021;184:4547-4563.e17 pubmed 出版商 |
Emmenegger M, De Cecco E, Hruska Plochan M, Eninger T, Schneider M, Barth M, et al. LAG3 is not expressed in human and murine neurons and does not modulate α-synucleinopathies. EMBO Mol Med. 2021;13:e14745 pubmed 出版商 |
Safren N, TANK E, Malik A, Chua J, Santoro N, Barmada S. Development of a specific live-cell assay for native autophagic flux. J Biol Chem. 2021;:101003 pubmed 出版商 |
Sahu B, Pihlajamaa P, Zhang K, Palin K, Ahonen S, Cervera A, et al. Human cell transformation by combined lineage conversion and oncogene expression. Oncogene. 2021;: pubmed 出版商 |
Kempf J, Knelles K, Hersbach B, Petrik D, Riedemann T, Bednárová V, et al. Heterogeneity of neurons reprogrammed from spinal cord astrocytes by the proneural factors Ascl1 and Neurogenin2. Cell Rep. 2021;36:109409 pubmed 出版商 |
Steinberg D, Repudi S, Saleem A, Kustanovich I, Viukov S, Abudiab B, et al. Modeling genetic epileptic encephalopathies using brain organoids. EMBO Mol Med. 2021;13:e13610 pubmed 出版商 |
Valiulahi P, Vidyawan V, Puspita L, Oh Y, Juwono V, Sittipo P, et al. Generation of caudal-type serotonin neurons and hindbrain-fate organoids from hPSCs. Stem Cell Reports. 2021;16:1938-1952 pubmed 出版商 |
Wegscheid M, Anastasaki C, Hartigan K, Cobb O, Papke J, Traber J, et al. Patient-derived iPSC-cerebral organoid modeling of the 17q11.2 microdeletion syndrome establishes CRLF3 as a critical regulator of neurogenesis. Cell Rep. 2021;36:109315 pubmed 出版商 |
Carola G, Malagarriga D, Calatayud C, Pons Espinal M, Blasco Agell L, Richaud Patin Y, et al. Parkinson's disease patient-specific neuronal networks carrying the LRRK2 G2019S mutation unveil early functional alterations that predate neurodegeneration. NPJ Parkinsons Dis. 2021;7:55 pubmed 出版商 |
Banfi F, Rubio A, Zaghi M, Massimino L, Fagnocchi G, Bellini E, et al. SETBP1 accumulation induces P53 inhibition and genotoxic stress in neural progenitors underlying neurodegeneration in Schinzel-Giedion syndrome. Nat Commun. 2021;12:4050 pubmed 出版商 |
Pardieck J, Harb M, Sakiyama Elbert S. Induction of Ventral Spinal V0 Interneurons from Mouse Embryonic Stem Cells. Stem Cells Dev. 2021;30:816-829 pubmed 出版商 |
Van Lent J, Verstraelen P, Asselbergh B, Adriaenssens E, Mateiu L, Verbist C, et al. Induced pluripotent stem cell-derived motor neurons of CMT type 2 patients reveal progressive mitochondrial dysfunction. Brain. 2021;144:2471-2485 pubmed 出版商 |
Sanchez C, Acker C, Gray A, Varadarajan M, Song C, Cochran N, et al. Genome-wide CRISPR screen identifies protein pathways modulating tau protein levels in neurons. Commun Biol. 2021;4:736 pubmed 出版商 |
Bueno C, Mart xed nez Morga M, Garc xed a Bernal D, Moraleda J, Mart xed nez S. Differentiation of human adult-derived stem cells towards a neural lineage involves a dedifferentiation event prior to differentiation to neural phenotypes. Sci Rep. 2021;11:12034 pubmed 出版商 |
Rimington R, Fleming J, Capel A, Wheeler P, Lewis M. Bioengineered model of the human motor unit with physiologically functional neuromuscular junctions. Sci Rep. 2021;11:11695 pubmed 出版商 |
Nakashima H, Tsujimura K, Irie K, Imamura T, Trujillo C, Ishizu M, et al. MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling. Cell Rep. 2021;35:109124 pubmed 出版商 |
Sundberg M, Pinson H, Smith R, Winden K, Venugopal P, Tai D, et al. 16p11.2 deletion is associated with hyperactivation of human iPSC-derived dopaminergic neuron networks and is rescued by RHOA inhibition in vitro. Nat Commun. 2021;12:2897 pubmed 出版商 |
Stykel M, Humphries K, Kamski Hennekam E, Buchner Duby B, Porte Trachsel N, Ryan T, et al. α-Synuclein mutation impairs processing of endomembrane compartments and promotes exocytosis and seeding of α-synuclein pathology. Cell Rep. 2021;35:109099 pubmed 出版商 |
Lafarga V, Sirozh O, Díaz López I, Galarreta A, Hisaoka M, Zarzuela E, et al. Widespread displacement of DNA- and RNA-binding factors underlies toxicity of arginine-rich cell-penetrating peptides. EMBO J. 2021;40:e103311 pubmed 出版商 |
Kim S, Lee S, Kim Y, Park J, Woo D, Kim D, et al. Tanc2-mediated mTOR inhibition balances mTORC1/2 signaling in the developing mouse brain and human neurons. Nat Commun. 2021;12:2695 pubmed 出版商 |
Zhu Y, Huang R, Wu Z, Song S, Cheng L, Zhu R. Deep learning-based predictive identification of neural stem cell differentiation. Nat Commun. 2021;12:2614 pubmed 出版商 |
Hara T, Toyoshima M, Hisano Y, Balan S, Iwayama Y, Aono H, et al. Glyoxalase I disruption and external carbonyl stress impair mitochondrial function in human induced pluripotent stem cells and derived neurons. Transl Psychiatry. 2021;11:275 pubmed 出版商 |
Kour S, Rajan D, Fortuna T, Anderson E, Ward C, Lee Y, et al. Loss of function mutations in GEMIN5 cause a neurodevelopmental disorder. Nat Commun. 2021;12:2558 pubmed 出版商 |
Hensel N, Cieri F, Santonicola P, Tapken I, Schüning T, Taiana M, et al. Impairment of the neurotrophic signaling hub B-Raf contributes to motoneuron degeneration in spinal muscular atrophy. Proc Natl Acad Sci U S A. 2021;118: pubmed 出版商 |
Schikora J, Kiwatrowski N, F xf6 rster N, Selbach L, Ostendorf F, Pallapies F, et al. A Propagated Skeleton Approach to High Throughput Screening of Neurite Outgrowth for In Vitro Parkinson's Disease Modelling. Cells. 2021;10: pubmed 出版商 |
Stoklund Dittlau K, Krasnow E, Fumagalli L, Vandoorne T, Baatsen P, Kerstens A, et al. Human motor units in microfluidic devices are impaired by FUS mutations and improved by HDAC6 inhibition. Stem Cell Reports. 2021;16:2213-2227 pubmed 出版商 |
Raj N, McEachin Z, Harousseau W, Zhou Y, Zhang F, Merritt Garza M, et al. Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis. Cell Rep. 2021;35:108991 pubmed 出版商 |
Nuñez J, Chen J, Pommier G, Cogan J, Replogle J, Adriaens C, et al. Genome-wide programmable transcriptional memory by CRISPR-based epigenome editing. Cell. 2021;184:2503-2519.e17 pubmed 出版商 |
Cannarozzo C, Fred S, Girych M, Biojone C, Enkavi G, R xf3 g T, et al. Cholesterol-recognition motifs in the transmembrane domain of the tyrosine kinase receptor family: The case of TRKB. Eur J Neurosci. 2021;53:3311-3322 pubmed 出版商 |
Avior Y, Ron S, Kroitorou D, Albeldas C, Lerner V, Corneo B, et al. Depression patient-derived cortical neurons reveal potential biomarkers for antidepressant response. Transl Psychiatry. 2021;11:201 pubmed 出版商 |
Chanoumidou K, Hern xe1 ndez Rodr xed guez B, Windener F, Thomas C, Stehling M, Mozafari S, et al. One-step Reprogramming of Human Fibroblasts into Oligodendrocyte-like Cells by SOX10, OLIG2, and NKX6.2. Stem Cell Reports. 2021;16:771-783 pubmed 出版商 |
Le Cann K, Foerster A, Rösseler C, Erickson A, Hautvast P, Giesselmann S, et al. The difficulty to model Huntington's disease in vitro using striatal medium spiny neurons differentiated from human induced pluripotent stem cells. Sci Rep. 2021;11:6934 pubmed 出版商 |
Boecker C, Goldsmith J, Dou D, Cajka G, Holzbaur E. Increased LRRK2 kinase activity alters neuronal autophagy by disrupting the axonal transport of autophagosomes. Curr Biol. 2021;31:2140-2154.e6 pubmed 出版商 |
Gong C, Zheng X, Guo F, Wang Y, Zhang S, Chen J, et al. Human spinal GABA neurons alleviate spasticity and improve locomotion in rats with spinal cord injury. Cell Rep. 2021;34:108889 pubmed 出版商 |
Brown S, Boussaad I, Jarazo J, Fitzgerald J, Antony P, Keatinge M, et al. PINK1 deficiency impairs adult neurogenesis of dopaminergic neurons. Sci Rep. 2021;11:6617 pubmed 出版商 |
SHERIDAN S, Thanos J, De Guzman R, McCrea L, Horng J, Fu T, et al. Umbilical cord blood-derived microglia-like cells to model COVID-19 exposure. Transl Psychiatry. 2021;11:179 pubmed 出版商 |
Manganas L, Durá I, Osenberg S, Semerci F, Tosun M, Mishra R, et al. BASP1 labels neural stem cells in the neurogenic niches of mammalian brain. Sci Rep. 2021;11:5546 pubmed 出版商 |
Vadodaria K, Mendes A, Mei A, Racha V, Erikson G, Shokhirev M, et al. Altered Neuronal Support and Inflammatory Response in Bipolar Disorder Patient-Derived Astrocytes. Stem Cell Reports. 2021;16:825-835 pubmed 出版商 |
Dong X, Yang L, Liu K, Ji X, Tang C, Li W, et al. Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment. Cell Rep. 2021;34:108802 pubmed 出版商 |
Casarotto P, Girych M, Fred S, Kovaleva V, Moliner R, Enkavi G, et al. Antidepressant drugs act by directly binding to TRKB neurotrophin receptors. Cell. 2021;184:1299-1313.e19 pubmed 出版商 |
Gelain F, Luo Z, Rioult M, Zhang S. Self-assembling peptide scaffolds in the clinic. NPJ Regen Med. 2021;6:9 pubmed 出版商 |
Boshans L, Soh H, Wood W, Nolan T, Mandoiu I, Yanagawa Y, et al. Direct reprogramming of oligodendrocyte precursor cells into GABAergic inhibitory neurons by a single homeodomain transcription factor Dlx2. Sci Rep. 2021;11:3552 pubmed 出版商 |
Zeng P, Hua Q, Gong J, Shi C, Pi X, Xie X, et al. Neonatal cortical astrocytes possess intrinsic potential in neuronal conversion in defined media. Acta Pharmacol Sin. 2021;42:1757-1768 pubmed 出版商 |
Haag D, Mack N, Benites Goncalves da Silva P, Statz B, Clark J, Tanabe K, et al. H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model. Cancer Cell. 2021;: pubmed 出版商 |
Trujillo C, Adams J, Negraes P, Carromeu C, Tejwani L, Acab A, et al. Pharmacological reversal of synaptic and network pathology in human MECP2-KO neurons and cortical organoids. EMBO Mol Med. 2021;13:e12523 pubmed 出版商 |
Yuan H, Hu H, Chen R, Mu W, Wang L, Li Y, et al. Premigratory neural crest stem cells generate enteric neurons populating the mouse colon and regulating peristalsis in tissue-engineered intestine. Stem Cells Transl Med. 2021;10:922-938 pubmed 出版商 |
Niceforo A, Marioli C, Colasuonno F, Petrini S, Massey K, Tartaglia M, et al. Altered cytoskeletal arrangement in induced pluripotent stem cells (iPSCs) and motor neurons from patients with riboflavin transporter deficiency. Dis Model Mech. 2021;: pubmed 出版商 |
Siebert J, Osterhout D. Select neurotrophins promote oligodendrocyte progenitor cell process outgrowth in the presence of chondroitin sulfate proteoglycans. J Neurosci Res. 2021;99:1009-1023 pubmed 出版商 |
Dodge J, Yu J, Sardi S, Shihabuddin L. Sterol auto-oxidation adversely affects human motor neuron viability and is a neuropathological feature of amyotrophic lateral sclerosis. Sci Rep. 2021;11:803 pubmed 出版商 |
Bae M, Roh J, Kim Y, Kim S, Han H, Yang E, et al. SLC6A20 transporter: a novel regulator of brain glycine homeostasis and NMDAR function. EMBO Mol Med. 2021;13:e12632 pubmed 出版商 |
Guhathakurta S, Kim J, ADAMS L, Basu S, Song M, Adler E, et al. Targeted attenuation of elevated histone marks at SNCA alleviates α-synuclein in Parkinson's disease. EMBO Mol Med. 2021;13:e12188 pubmed 出版商 |
Xiong C, Chua K, Stage T, Priotti J, Kim J, Altman Merino A, et al. Human Induced Pluripotent Stem Cell Derived Sensory Neurons are Sensitive to the Neurotoxic Effects of Paclitaxel. Clin Transl Sci. 2021;14:568-581 pubmed 出版商 |
Fukusumi H, Togo K, Sumida M, Nakamori M, Obika S, Baba K, et al. Alpha-synuclein dynamics in induced pluripotent stem cell-derived dopaminergic neurons from a Parkinson's disease patient (PARK4) with SNCA triplication. FEBS Open Bio. 2021;11:354-366 pubmed 出版商 |
Stertz L, Di Re J, Pei G, Fries G, Mendez E, Li S, et al. Convergent genomic and pharmacological evidence of PI3K/GSK3 signaling alterations in neurons from schizophrenia patients. Neuropsychopharmacology. 2021;46:673-682 pubmed 出版商 |
Huang Y, Tsubota S, Nishio N, Takahashi Y, Kadomatsu K. Combination of tumor necrosis factor-α and epidermal growth factor induces the adrenergic-to-mesenchymal transdifferentiation in SH-SY5Y neuroblastoma cells. Cancer Sci. 2021;112:715-724 pubmed 出版商 |
Wang M, Li A, Sekiya M, Beckmann N, Quan X, Schrode N, et al. Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease. Neuron. 2021;109:257-272.e14 pubmed 出版商 |
Xiong M, Tao Y, Gao Q, Feng B, Yan W, Zhou Y, et al. Human Stem Cell-Derived Neurons Repair Circuits and Restore Neural Function. Cell Stem Cell. 2021;28:112-126.e6 pubmed 出版商 |
Cates K, McCoy M, Kwon J, Liu Y, Abernathy D, Zhang B, et al. Deconstructing Stepwise Fate Conversion of Human Fibroblasts to Neurons by MicroRNAs. Cell Stem Cell. 2021;28:127-140.e9 pubmed 出版商 |
Lingel A, Lin H, Gavriel Y, Weaver E, Polepole P, Lopez V, et al. Amyloid precursor protein is a restriction factor that protects against Zika virus infection in mammalian brains. J Biol Chem. 2020;295:17114-17127 pubmed 出版商 |
Qin T, Yuan Z, Yu J, Fu X, Deng X, Fu Q, et al. Saikosaponin-d impedes hippocampal neurogenesis and causes cognitive deficits by inhibiting the survival of neural stem/progenitor cells via neurotrophin receptor signaling in mice. Clin Transl Med. 2020;10:e243 pubmed 出版商 |
Ryan S, Jordan Sciutto K, Anderson S. Protocol for Tri-culture of hiPSC-Derived Neurons, Astrocytes, and Microglia. STAR Protoc. 2020;1:100190 pubmed 出版商 |
Zhang D, Liu C, Li H, Jiao J. Deficiency of STING Signaling in Embryonic Cerebral Cortex Leads to Neurogenic Abnormalities and Autistic-Like Behaviors. Adv Sci (Weinh). 2020;7:2002117 pubmed 出版商 |
Ouwendijk W, Depledge D, Rajbhandari L, Lenac Rovis T, Jonjic S, Breuer J, et al. Varicella-zoster virus VLT-ORF63 fusion transcript induces broad viral gene expression during reactivation from neuronal latency. Nat Commun. 2020;11:6324 pubmed 出版商 |
Park Y, Snook J, Zhuang I, Shen G, Frankfort B. Optimized culture of retinal ganglion cells and amacrine cells from adult mice. PLoS ONE. 2020;15:e0242426 pubmed 出版商 |
Cooper Knock J, Zhang S, Kenna K, Moll T, Franklin J, Allen S, et al. Rare Variant Burden Analysis within Enhancers Identifies CAV1 as an ALS Risk Gene. Cell Rep. 2020;33:108456 pubmed 出版商 |
Black J, McCutcheon S, Dube S, Barrera A, Klann T, Rice G, et al. Master Regulators and Cofactors of Human Neuronal Cell Fate Specification Identified by CRISPR Gene Activation Screens. Cell Rep. 2020;33:108460 pubmed 出版商 |
Sarraf S, Shah H, Kanfer G, Pickrell A, Holtzclaw L, Ward M, et al. Loss of TAX1BP1-Directed Autophagy Results in Protein Aggregate Accumulation in the Brain. Mol Cell. 2020;80:779-795.e10 pubmed 出版商 |
Truv xe9 K, Parris T, Vizlin Hodzic D, Salmela S, Berger E, xc5 gren H, et al. Identification of candidate genetic variants and altered protein expression in neural stem and mature neural cells support altered microtubule function to be an essential component in bipolar disorder. Transl Psychiatry. 2020;10:390 pubmed 出版商 |
Renner H, Grabos M, Becker K, Kagermeier T, Wu J, Otto M, et al. A fully automated high-throughput workflow for 3D-based chemical screening in human midbrain organoids. elife. 2020;9: pubmed 出版商 |
Zhang T, Periz G, Lu Y, Wang J. USP7 regulates ALS-associated proteotoxicity and quality control through the NEDD4L-SMAD pathway. Proc Natl Acad Sci U S A. 2020;117:28114-28125 pubmed 出版商 |
Ebert L, Yu W, Gargett T, Toubia J, Kollis P, Tea M, et al. Endothelial, pericyte and tumor cell expression in glioblastoma identifies fibroblast activation protein (FAP) as an excellent target for immunotherapy. Clin Transl Immunology. 2020;9:e1191 pubmed 出版商 |
Chen Y, Kunath T, Simpson J, Homer N, Sylantyev S. Synaptic signalling in a network of dopamine neurons: what prevents proper intercellular crosstalk?. FEBS Lett. 2020;594:3272-3292 pubmed 出版商 |
Kinarivala N, Morsy A, Patel R, Carmona A, Sajib M, Raut S, et al. An iPSC-Derived Neuron Model of CLN3 Disease Facilitates Small Molecule Phenotypic Screening. ACS Pharmacol Transl Sci. 2020;3:931-947 pubmed 出版商 |
Sun J, Huang Y, Gong J, Wang J, Fan Y, Cai J, et al. Transplantation of hPSC-derived pericyte-like cells promotes functional recovery in ischemic stroke mice. Nat Commun. 2020;11:5196 pubmed 出版商 |
Panagiotakopoulou V, Ivanyuk D, De Cicco S, Haq W, Arsic A, Yu C, et al. Interferon-γ signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells. Nat Commun. 2020;11:5163 pubmed 出版商 |
Fernandes H, Patikas N, Foskolou S, Field S, Park J, Byrne M, et al. Single-Cell Transcriptomics of Parkinson's Disease Human In Vitro Models Reveals Dopamine Neuron-Specific Stress Responses. Cell Rep. 2020;33:108263 pubmed 出版商 |
Dodge J, Jensen E, Yu J, Sardi S, Bialas A, Taksir T, et al. Neutral Lipid Cacostasis Contributes to Disease Pathogenesis in Amyotrophic Lateral Sclerosis. J Neurosci. 2020;40:9137-9147 pubmed 出版商 |
Guerenne Del Ben T, Couderc V, Duponchel L, Sol V, Leproux P, Petit J. Multiplex coherent anti-Stokes Raman scattering microspectroscopy detection of lipid droplets in cancer cells expressing TrkB. Sci Rep. 2020;10:16749 pubmed 出版商 |
Lingel A, Lin H, Gavriel Y, Weaver E, Polepole P, Lopez V, et al. Amyloid precursor protein is a restriction factor that protects against Zika virus infection in mammalian brains. J Biol Chem. 2020;295:17114-17127 pubmed 出版商 |
Jacob F, Pather S, Huang W, Zhang F, Wong S, Zhou H, et al. Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism Predominates in Choroid Plexus Epithelium. Cell Stem Cell. 2020;27:937-950.e9 pubmed 出版商 |
Savier E, Dunbar J, Cheung K, Reber M. New insights on the modeling of the molecular mechanisms underlying neural maps alignment in the midbrain. elife. 2020;9: pubmed 出版商 |
Khan T, Revah O, Gordon A, Yoon S, Krawisz A, Goold C, et al. Neuronal defects in a human cellular model of 22q11.2 deletion syndrome. Nat Med. 2020;26:1888-1898 pubmed 出版商 |
Schwartzentruber A, Boschian C, Lopes F, Myszczynska M, New E, Beyrath J, et al. Oxidative switch drives mitophagy defects in dopaminergic parkin mutant patient neurons. Sci Rep. 2020;10:15485 pubmed 出版商 |
Kobayashi G, Musso C, Moreira D, Pontillo Guimar xe3 es G, Hsia G, Caires J xfa nior L, et al. Recapitulation of Neural Crest Specification and EMT via Induction from Neural Plate Border-like Cells. Stem Cell Reports. 2020;15:776-788 pubmed 出版商 |
Liang K, Kristiansen C, Mostafavi S, Vatne G, Zantingh G, Kianian A, et al. Disease-specific phenotypes in iPSC-derived neural stem cells with POLG mutations. EMBO Mol Med. 2020;12:e12146 pubmed 出版商 |
Mazzara P, Muggeo S, Luoni M, Massimino L, Zaghi M, Valverde P, et al. Frataxin gene editing rescues Friedreich's ataxia pathology in dorsal root ganglia organoid-derived sensory neurons. Nat Commun. 2020;11:4178 pubmed 出版商 |
Sepehrimanesh M, Ding B. Generation and optimization of highly pure motor neurons from human induced pluripotent stem cells via lentiviral delivery of transcription factors. Am J Physiol Cell Physiol. 2020;319:C771-C780 pubmed 出版商 |
Jacob F, Pather S, Huang W, Wong S, Zhou H, Zhang F, et al. Human Pluripotent Stem Cell-Derived Neural Cells and Brain Organoids Reveal SARS-CoV-2 Neurotropism. bioRxiv. 2020;: pubmed 出版商 |
Zhang B, Chu H, Han S, Shuai H, Deng J, Hu Y, et al. SARS-CoV-2 infects human neural progenitor cells and brain organoids. Cell Res. 2020;30:928-931 pubmed 出版商 |
Spampinato S, Merlo S, Fagone E, Fruciano M, Sano Y, Kanda T, et al. Reciprocal Interplay Between Astrocytes and CD4+ Cells Affects Blood-Brain Barrier and Neuronal Function in Response to β Amyloid. Front Mol Neurosci. 2020;13:120 pubmed 出版商 |
Armache A, Yang S, Martinez de Paz A, Robbins L, Durmaz C, Cheong J, et al. Histone H3.3 phosphorylation amplifies stimulation-induced transcription. Nature. 2020;583:852-857 pubmed 出版商 |
Hsu C, Xu J, Brinkhof B, Wang H, Cui Z, Huang W, et al. A single-cell Raman-based platform to identify developmental stages of human pluripotent stem cell-derived neurons. Proc Natl Acad Sci U S A. 2020;117:18412-18423 pubmed 出版商 |
Garone M, Alfano V, Salvatori B, Braccia C, Peruzzi G, Colantoni A, et al. Proteomics analysis of FUS mutant human motoneurons reveals altered regulation of cytoskeleton and other ALS-linked proteins via 3'UTR binding. Sci Rep. 2020;10:11827 pubmed 出版商 |
Wang T, Medynets M, Johnson K, Doucet O Hare T, DiSanza B, Li W, et al. Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway. Proc Natl Acad Sci U S A. 2020;117:17842-17853 pubmed 出版商 |
Moses C, Hodgetts S, Nugent F, Ben Ary G, Park K, Blancafort P, et al. Transcriptional repression of PTEN in neural cells using CRISPR/dCas9 epigenetic editing. Sci Rep. 2020;10:11393 pubmed 出版商 |
Begovich K, Vu A, Yeo G, Wilhelm J. Conserved metabolite regulation of stress granule assembly via AdoMet. J Cell Biol. 2020;219: pubmed 出版商 |
de la Fuente S, Sansa A, Hidalgo I, Vivancos N, Romero Guevara R, Garcera A, et al. Calpain system is altered in survival motor neuron-reduced cells from in vitro and in vivo spinal muscular atrophy models. Cell Death Dis. 2020;11:487 pubmed 出版商 |
Lee H, Lee H, Lee B, Gerovska D, Park S, Zaehres H, et al. Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model. elife. 2020;9: pubmed 出版商 |
Nzou G, Wicks R, VanOstrand N, Mekky G, Seale S, El Taibany A, et al. Multicellular 3D Neurovascular Unit Model for Assessing Hypoxia and Neuroinflammation Induced Blood-Brain Barrier Dysfunction. Sci Rep. 2020;10:9766 pubmed 出版商 |
Buchholz D, Carroll T, Kocabas A, Zhu X, Behesti H, Faust P, et al. Novel genetic features of human and mouse Purkinje cell differentiation defined by comparative transcriptomics. Proc Natl Acad Sci U S A. 2020;117:15085-15095 pubmed 出版商 |
Knupp A, Mishra S, Martinez R, Braggin J, Szabó M, Kinoshita C, et al. Depletion of the AD Risk Gene SORL1 Selectively Impairs Neuronal Endosomal Traffic Independent of Amyloidogenic APP Processing. Cell Rep. 2020;31:107719 pubmed 出版商 |
Fatima A, Irmak D, Noormohammadi A, Rinschen M, Das A, Leidecker O, et al. The ubiquitin-conjugating enzyme UBE2K determines neurogenic potential through histone H3 in human embryonic stem cells. Commun Biol. 2020;3:262 pubmed 出版商 |
Zayed M, Iohara K, Watanabe H, Nakashima M. CCR3 antagonist protects against induced cellular senescence and promotes rejuvenation in periodontal ligament cells for stimulating pulp regeneration in the aged dog. Sci Rep. 2020;10:8631 pubmed 出版商 |
Bowers M, Liang T, Gonzalez Bohorquez D, Zocher S, Jaeger B, Kovacs W, et al. FASN-Dependent Lipid Metabolism Links Neurogenic Stem/Progenitor Cell Activity to Learning and Memory Deficits. Cell Stem Cell. 2020;27:98-109.e11 pubmed 出版商 |
McEachin Z, Gendron T, Raj N, García Murias M, Banerjee A, Purcell R, et al. Chimeric Peptide Species Contribute to Divergent Dipeptide Repeat Pathology in c9ALS/FTD and SCA36. Neuron. 2020;107:292-305.e6 pubmed 出版商 |
Yang L, Jurczak K, Ge L, van Rijn P. High-Throughput Screening and Hierarchical Topography-Mediated Neural Differentiation of Mesenchymal Stem Cells. Adv Healthc Mater. 2020;9:e2000117 pubmed 出版商 |
Morikawa K, Furuhashi K, de Sena Tomás C, Garcia Garcia A, Bekdash R, Klein A, et al. Photoactivatable Cre recombinase 3.0 for in vivo mouse applications. Nat Commun. 2020;11:2141 pubmed 出版商 |
Stack E, McMurray S, McMurray G, Wade J, Clark M, Young G, et al. In vitro affinity optimization of an anti-BDNF monoclonal antibody translates to improved potency in targeting chronic pain states in vivo. MAbs. 2020;12:1755000 pubmed 出版商 |
Vagaska B, Gillham O, Ferretti P. Modelling human CNS injury with human neural stem cells in 2- and 3-Dimensional cultures. Sci Rep. 2020;10:6785 pubmed 出版商 |
Licursi V, Anzellotti S, Favaro J, Sineri S, Carucci N, Cundari E, et al. X-ray irradiated cultures of mouse cortical neural stem/progenitor cells recover cell viability and proliferation with dose-dependent kinetics. Sci Rep. 2020;10:6562 pubmed 出版商 |
Zhan J, Li X, Luo D, Hou Y, Hou Y, Chen S, et al. Polydatin promotes the neuronal differentiation of bone marrow mesenchymal stem cells in vitro and in vivo: Involvement of Nrf2 signalling pathway. J Cell Mol Med. 2020;24:5317-5329 pubmed 出版商 |
Nguyen T, Wu K, Pandey S, Lehr A, Li Y, Bemben M, et al. A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y. Neuron. 2020;106:759-768.e7 pubmed 出版商 |
Ryan S, Gonzalez M, Garifallou J, Bennett F, WILLIAMS K, Sotuyo N, et al. Neuroinflammation and EIF2 Signaling Persist despite Antiretroviral Treatment in an hiPSC Tri-culture Model of HIV Infection. Stem Cell Reports. 2020;14:703-716 pubmed 出版商 |
Sun X, Bernstein M, Meng M, Rao S, Sørensen A, Yao L, et al. Functionally Distinct Neuronal Ensembles within the Memory Engram. Cell. 2020;181:410-423.e17 pubmed 出版商 |
Tai C, Chang C, Yu G, Lopez I, Yu X, Wang X, et al. Tau Reduction Prevents Key Features of Autism in Mouse Models. Neuron. 2020;106:421-437.e11 pubmed 出版商 |
Bardelli D, Sassone F, Colombrita C, Volpe C, Gumina V, Peverelli S, et al. Reprogramming fibroblasts and peripheral blood cells from a C9ORF72 patient: A proof-of-principle study. J Cell Mol Med. 2020;24:4051-4060 pubmed 出版商 |
Sharma R, Smits I, de la Vega L, Lee C, Willerth S. 3D Bioprinting Pluripotent Stem Cell Derived Neural Tissues Using a Novel Fibrin Bioink Containing Drug Releasing Microspheres. Front Bioeng Biotechnol. 2020;8:57 pubmed 出版商 |
Vermilyea S, Babinski A, Tran N, To S, Guthrie S, Kluss J, et al. In Vitro CRISPR/Cas9-Directed Gene Editing to Model LRRK2 G2019S Parkinson's Disease in Common Marmosets. Sci Rep. 2020;10:3447 pubmed 出版商 |
Andrade N, Ramic M, Esanov R, Liu W, Rybin M, Gaidosh G, et al. Dipeptide repeat proteins inhibit homology-directed DNA double strand break repair in C9ORF72 ALS/FTD. Mol Neurodegener. 2020;15:13 pubmed 出版商 |
Shen W, Wang Q, Liu Y, Marchetto M, Linker S, Lu S, et al. Synaptotagmin-7 is a key factor for bipolar-like behavioral abnormalities in mice. Proc Natl Acad Sci U S A. 2020;117:4392-4399 pubmed 出版商 |
Fellows A, Rhymes E, Gibbs K, Greensmith L, Schiavo G. IGF1R regulates retrograde axonal transport of signalling endosomes in motor neurons. EMBO Rep. 2020;21:e49129 pubmed 出版商 |
Channakkar A, Singh T, Pattnaik B, Gupta K, Seth P, Adlakha Y. MiRNA-137-mediated modulation of mitochondrial dynamics regulates human neural stem cell fate. Stem Cells. 2020;38:683-697 pubmed 出版商 |
Bessières B, Travaglia A, Mowery T, Zhang X, Alberini C. Early life experiences selectively mature learning and memory abilities. Nat Commun. 2020;11:628 pubmed 出版商 |
Satir T, Nazir F, Vizlin Hodzic D, Hardselius E, Blennow K, Wray S, et al. Accelerated neuronal and synaptic maturation by BrainPhys medium increases Aβ secretion and alters Aβ peptide ratios from iPSC-derived cortical neurons. Sci Rep. 2020;10:601 pubmed 出版商 |
Cifelli J, Berg K, Yang J. Benzothiazole amphiphiles promote RasGRF1-associated dendritic spine formation in human stem cell-derived neurons. FEBS Open Bio. 2020;10:386-395 pubmed 出版商 |
Henderson M, Sedor S, McGeary I, Cornblath E, Peng C, Riddle D, et al. Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult. Neuron. 2020;105:822-836.e7 pubmed 出版商 |
Fox L, Kim K, Johnson C, Chen S, Croce K, Victor M, et al. Huntington's Disease Pathogenesis Is Modified In Vivo by Alfy/Wdfy3 and Selective Macroautophagy. Neuron. 2020;105:813-821.e6 pubmed 出版商 |
Capuano R, Talarico R, Spitalieri P, Paolesse R, Novelli G, Sangiuolo F, et al. GC/MS-based Analysis of Volatile Metabolic Profile Along in vitro Differentiation of Human Induced Pluripotent Stem Cells. Bio Protoc. 2017;7:e2642 pubmed 出版商 |
Joung D, Truong V, Neitzke C, Guo S, Walsh P, Monat J, et al. 3D Printed Stem-Cell Derived Neural Progenitors Generate Spinal Cord Scaffolds. Adv Funct Mater. 2018;28: pubmed 出版商 |
Wu P, Fann M, Tran T, Chen S, Devina T, Cheng I, et al. Assessing the therapeutic potential of Graptopetalum paraguayense on Alzheimer's disease using patient iPSC-derived neurons. Sci Rep. 2019;9:19301 pubmed 出版商 |
Shiga Y, Shiga A, Mesci P, Kwon H, Brifault C, Kim J, et al. Tissue-type plasminogen activator-primed human iPSC-derived neural progenitor cells promote motor recovery after severe spinal cord injury. Sci Rep. 2019;9:19291 pubmed 出版商 |
Young Baird S, Lourenço M, Elder M, Klann E, Liebau S, Dever T. Suppression of MEHMO Syndrome Mutation in eIF2 by Small Molecule ISRIB. Mol Cell. 2019;: pubmed 出版商 |
de Rus Jacquet A. Preparation and Co-Culture of iPSC-Derived Dopaminergic Neurons and Astrocytes. Curr Protoc Cell Biol. 2019;85:e98 pubmed 出版商 |
Pu J, Dai S, Gao T, Hu J, Fang Y, Zheng R, et al. Nystagmus-related FRMD7 gene influences the maturation and complexities of neuronal processes in human neurons. Brain Behav. 2019;9:e01473 pubmed 出版商 |
Moritake H, Saito Y, Sawa D, Sameshima N, Yamada A, Kinoshita M, et al. TAE226, a dual inhibitor of focal adhesion kinase and insulin-like growth factor-I receptor, is effective for Ewing sarcoma. Cancer Med. 2019;8:7809-7821 pubmed 出版商 |
Fred S, Laukkanen L, Brunello C, Vesa L, Göös H, Cardon I, et al. Pharmacologically diverse antidepressants facilitate TRKB receptor activation by disrupting its interaction with the endocytic adaptor complex AP-2. J Biol Chem. 2019;294:18150-18161 pubmed 出版商 |
Li Q, Huang Q. Single-cell qPCR demonstrates that Repsox treatment changes cell fate from endoderm to neuroectoderm and disrupts epithelial-mesenchymal transition. PLoS ONE. 2019;14:e0223724 pubmed 出版商 |
Cozzi A, Orellana D, Santambrogio P, Rubio A, Cancellieri C, Giannelli S, et al. Stem Cell Modeling of Neuroferritinopathy Reveals Iron as a Determinant of Senescence and Ferroptosis during Neuronal Aging. Stem Cell Reports. 2019;13:832-846 pubmed 出版商 |
Patzke C, Brockmann M, Dai J, Gan K, Grauel M, Fenske P, et al. Neuromodulator Signaling Bidirectionally Controls Vesicle Numbers in Human Synapses. Cell. 2019;179:498-513.e22 pubmed 出版商 |
Kim J, Lana B, Torelli S, Ryan D, Catapano F, Ala P, et al. A new patient-derived iPSC model for dystroglycanopathies validates a compound that increases glycosylation of α-dystroglycan. EMBO Rep. 2019;20:e47967 pubmed 出版商 |
Sohn P, Huang C, Yan R, Fan L, Tracy T, Camargo C, et al. Pathogenic Tau Impairs Axon Initial Segment Plasticity and Excitability Homeostasis. Neuron. 2019;104:458-470.e5 pubmed 出版商 |
Liao Y, Fernandopulle M, Wang G, Choi H, Hao L, Drerup C, et al. RNA Granules Hitchhike on Lysosomes for Long-Distance Transport, Using Annexin A11 as a Molecular Tether. Cell. 2019;179:147-164.e20 pubmed 出版商 |
Berger J, Singh P, Khrimian L, Morgan D, Chowdhury S, Arteaga Solis E, et al. Mediation of the Acute Stress Response by the Skeleton. Cell Metab. 2019;30:890-902.e8 pubmed 出版商 |
Vandoorne T, Veys K, Guo W, Sicart A, Vints K, Swijsen A, et al. Differentiation but not ALS mutations in FUS rewires motor neuron metabolism. Nat Commun. 2019;10:4147 pubmed 出版商 |
Tiihonen J, Koskuvi M, Storvik M, Hyötyläinen I, Gao Y, Puttonen K, et al. Sex-specific transcriptional and proteomic signatures in schizophrenia. Nat Commun. 2019;10:3933 pubmed 出版商 |
Griffiths B, Ouyang Y, Xu L, Sun X, Giffard R, Stary C. Postinjury Inhibition of miR-181a Promotes Restoration of Hippocampal CA1 Neurons after Transient Forebrain Ischemia in Rats. Eneuro. 2019;6: pubmed 出版商 |
Tian R, Gachechiladze M, Ludwig C, Laurie M, Hong J, Nathaniel D, et al. CRISPR Interference-Based Platform for Multimodal Genetic Screens in Human iPSC-Derived Neurons. Neuron. 2019;104:239-255.e12 pubmed 出版商 |
Saadipour K, Tiberi A, Lombardo S, Grajales E, Montroull L, Mañucat Tan N, et al. Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor. Mol Cell Neurosci. 2019;99:103395 pubmed 出版商 |
Dubessy A, Mazuir E, Rappeneau Q, Ou S, Abi Ghanem C, Piquand K, et al. Role of a Contactin multi-molecular complex secreted by oligodendrocytes in nodal protein clustering in the CNS. Glia. 2019;67:2248-2263 pubmed 出版商 |
Fang M, Markmiller S, Vu A, Javaherian A, Dowdle W, Jolivet P, et al. Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD. Neuron. 2019;: pubmed 出版商 |
Sridharan B, Hubbs C, Llamosas N, Kilinc M, Singhera F, Willems E, et al. A Simple Procedure for Creating Scalable Phenotypic Screening Assays in Human Neurons. Sci Rep. 2019;9:9000 pubmed 出版商 |
Won H, Huang J, Opland C, Hartl C, Geschwind D. Human evolved regulatory elements modulate genes involved in cortical expansion and neurodevelopmental disease susceptibility. Nat Commun. 2019;10:2396 pubmed 出版商 |
An D, Fujiki R, Iannitelli D, Smerdon J, Maity S, Rose M, et al. Stem cell-derived cranial and spinal motor neurons reveal proteostatic differences between ALS resistant and sensitive motor neurons. elife. 2019;8: pubmed 出版商 |
Xu R, Brawner A, Li S, Liu J, Kim H, Xue H, et al. OLIG2 Drives Abnormal Neurodevelopmental Phenotypes in Human iPSC-Based Organoid and Chimeric Mouse Models of Down Syndrome. Cell Stem Cell. 2019;: pubmed 出版商 |
Geraghty A, Gibson E, Ghanem R, Greene J, Ocampo A, Goldstein A, et al. Loss of Adaptive Myelination Contributes to Methotrexate Chemotherapy-Related Cognitive Impairment. Neuron. 2019;: pubmed 出版商 |
Tischbein M, Baron D, Lin Y, Gall K, Landers J, Fallini C, et al. The RNA-binding protein FUS/TLS undergoes calcium-mediated nuclear egress during excitotoxic stress and is required for GRIA2 mRNA processing. J Biol Chem. 2019;: pubmed 出版商 |
Calatayud C, Carola G, Fernandez Carasa I, Valtorta M, Jimenez Delgado S, Diaz M, et al. CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons. Sci Rep. 2019;9:6811 pubmed 出版商 |
Levy M, Boulle F, Emerit M, Poilbout C, Steinbusch H, van den Hove D, et al. 5-HTT independent effects of fluoxetine on neuroplasticity. Sci Rep. 2019;9:6311 pubmed 出版商 |
Xiang J, Wang Z, Ahn E, Liu X, Yu S, Manfredsson F, et al. Delta-secretase-cleaved Tau antagonizes TrkB neurotrophic signalings, mediating Alzheimer's disease pathologies. Proc Natl Acad Sci U S A. 2019;116:9094-9102 pubmed 出版商 |
Siddiqi F, Menzies F, Lopez A, Stamatakou E, Karabiyik C, Ureshino R, et al. Felodipine induces autophagy in mouse brains with pharmacokinetics amenable to repurposing. Nat Commun. 2019;10:1817 pubmed 出版商 |
Smits L, Reinhardt L, Reinhardt P, Glatza M, Monzel A, Stanslowsky N, et al. Modeling Parkinson's disease in midbrain-like organoids. NPJ Parkinsons Dis. 2019;5:5 pubmed 出版商 |
Robinson M, Valente K, Willerth S. A Novel Toolkit for Characterizing the Mechanical and Electrical Properties of Engineered Neural Tissues. Biosensors (Basel). 2019;9: pubmed 出版商 |
Taylor Whiteley T, Le Maitre C, Duce J, Dalton C, Smith D. Recapitulating Parkinson's disease pathology in a three-dimensional human neural cell culture model. Dis Model Mech. 2019;12: pubmed 出版商 |
Zhao Y, Sun X, Hu D, Prosdocimo D, Hoppel C, Jain M, et al. ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects. Nat Commun. 2019;10:1371 pubmed 出版商 |
Fenske P, Grauel M, Brockmann M, Dorrn A, Trimbuch T, Rosenmund C. Autaptic cultures of human induced neurons as a versatile platform for studying synaptic function and neuronal morphology. Sci Rep. 2019;9:4890 pubmed 出版商 |
Ajmone Cat M, Onori A, Toselli C, Stronati E, Morlando M, Bozzoni I, et al. Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death. Sci Rep. 2019;9:4572 pubmed 出版商 |
Zou T, Gao L, Zeng Y, Li Q, Li Y, Chen S, et al. Organoid-derived C-Kit+/SSEA4- human retinal progenitor cells promote a protective retinal microenvironment during transplantation in rodents. Nat Commun. 2019;10:1205 pubmed 出版商 |
Gao L, Huang S, Zhang H, Hua W, Xin S, Cheng L, et al. Suppression of glioblastoma by a drug cocktail reprogramming tumor cells into neuronal like cells. Sci Rep. 2019;9:3462 pubmed 出版商 |
Malik B, Devine H, Patani R, La Spada A, Hanna M, Greensmith L. Gene expression analysis reveals early dysregulation of disease pathways and links Chmp7 to pathogenesis of spinal and bulbar muscular atrophy. Sci Rep. 2019;9:3539 pubmed 出版商 |
Baron D, Matheny T, Lin Y, Leszyk J, Kenna K, Gall K, et al. Quantitative proteomics identifies proteins that resist translational repression and become dysregulated in ALS-FUS. Hum Mol Genet. 2019;: pubmed 出版商 |
Zhu W, Zhang B, Li M, Mo F, Mi T, Wu Y, et al. Precisely controlling endogenous protein dosage in hPSCs and derivatives to model FOXG1 syndrome. Nat Commun. 2019;10:928 pubmed 出版商 |
Kane K, Moreno E, Hachi S, Walter M, Jarazo J, Oliveira M, et al. Automated microfluidic cell culture of stem cell derived dopaminergic neurons. Sci Rep. 2019;9:1796 pubmed 出版商 |
Sellgren C, Gracias J, Watmuff B, Biag J, Thanos J, Whittredge P, et al. Increased synapse elimination by microglia in schizophrenia patient-derived models of synaptic pruning. Nat Neurosci. 2019;22:374-385 pubmed 出版商 |
Seo J, Jung Y, Kim D, Ryu H, Lee J, Kim S, et al. DAP5 increases axonal outgrowth of hippocampal neurons by enhancing the cap-independent translation of DSCR1.4 mRNA. Cell Death Dis. 2019;10:49 pubmed 出版商 |
Bolognin S, Fossépré M, Qing X, Jarazo J, Scancar J, Moreno E, et al. 3D Cultures of Parkinson's Disease-Specific Dopaminergic Neurons for High Content Phenotyping and Drug Testing. Adv Sci (Weinh). 2019;6:1800927 pubmed 出版商 |
Matsuda T, Irie T, Katsurabayashi S, Hayashi Y, Nagai T, Hamazaki N, et al. Pioneer Factor NeuroD1 Rearranges Transcriptional and Epigenetic Profiles to Execute Microglia-Neuron Conversion. Neuron. 2019;101:472-485.e7 pubmed 出版商 |
Daniels B, Kofman S, Smith J, Norris G, Snyder A, Kolb J, et al. The Nucleotide Sensor ZBP1 and Kinase RIPK3 Induce the Enzyme IRG1 to Promote an Antiviral Metabolic State in Neurons. Immunity. 2019;50:64-76.e4 pubmed 出版商 |
Yoon S, Elahi L, Pasca A, Marton R, Gordon A, Revah O, et al. Reliability of human cortical organoid generation. Nat Methods. 2019;16:75-78 pubmed 出版商 |
Jiang S, Wen N, Li Z, Dube U, Del Aguila J, Budde J, et al. Integrative system biology analyses of CRISPR-edited iPSC-derived neurons and human brains reveal deficiencies of presynaptic signaling in FTLD and PSP. Transl Psychiatry. 2018;8:265 pubmed 出版商 |
Swarup V, Hinz F, Rexach J, Noguchi K, Toyoshiba H, Oda A, et al. Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia. Nat Med. 2019;25:152-164 pubmed 出版商 |
Russell L, Swanner J, Jaime Ramirez A, Wang Y, Sprague A, Banasavadi Siddegowda Y, et al. PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance. Nat Commun. 2018;9:5006 pubmed 出版商 |
Chen Y, Dolt K, Kriek M, Baker T, Downey P, Drummond N, et al. Engineering synucleinopathy-resistant human dopaminergic neurons by CRISPR-mediated deletion of the SNCA gene. Eur J Neurosci. 2018;: pubmed 出版商 |
Sánchez Iglesias S, Fernández Liste A, Guillín Amarelle C, Rabano A, Rodriguez Cañete L, González Méndez B, et al. Does Seipin Play a Role in Oxidative Stress Protection and Peroxisome Biogenesis? New Insights from Human Brain Autopsies. Neuroscience. 2019;396:119-137 pubmed 出版商 |
Bayo Puxan N, Terrasso A, Creyssels S, Simão D, Begon Pescia C, Lavigne M, et al. Lysosomal and network alterations in human mucopolysaccharidosis type VII iPSC-derived neurons. Sci Rep. 2018;8:16644 pubmed 出版商 |
Srikanth P, Lagomarsino V, PEARSE R, Liao M, Ghosh S, Nehme R, et al. Convergence of independent DISC1 mutations on impaired neurite growth via decreased UNC5D expression. Transl Psychiatry. 2018;8:245 pubmed 出版商 |
Blanco Suarez E, Liu T, Kopelevich A, Allen N. Astrocyte-Secreted Chordin-like 1 Drives Synapse Maturation and Limits Plasticity by Increasing Synaptic GluA2 AMPA Receptors. Neuron. 2018;100:1116-1132.e13 pubmed 出版商 |
George J, Nagel D, Waller S, Hill E, Parri H, Coleman M, et al. A closer look at neuron interaction with track-etched microporous membranes. Sci Rep. 2018;8:15552 pubmed 出版商 |
Chowdhury A, Caroni P. Time units for learning involving maintenance of system-wide cFos expression in neuronal assemblies. Nat Commun. 2018;9:4122 pubmed 出版商 |
Shen J, Xiao R, Bair J, Wang F, Vandenberghe L, Dartt D, et al. Novel engineered, membrane-localized variants of vascular endothelial growth factor (VEGF) protect retinal ganglion cells: a proof-of-concept study. Cell Death Dis. 2018;9:1018 pubmed 出版商 |
Shen C, Liu Y, Yu H, Gulbranson D, Kogut I, Bilousova G, et al. The N-peptide-binding mode is critical to Munc18-1 function in synaptic exocytosis. J Biol Chem. 2018;293:18309-18317 pubmed 出版商 |
Aron R, Pellegrini P, Green E, Maddison D, Opoku Nsiah K, Wong J, et al. Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington's disease. Nat Commun. 2018;9:3191 pubmed 出版商 |
Wang H, Guo W, Mitra J, Hegde P, Vandoorne T, Eckelmann B, et al. Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis. Nat Commun. 2018;9:3683 pubmed 出版商 |
Sloan S, Andersen J, Pasca A, Birey F, Paşca S. Generation and assembly of human brain region-specific three-dimensional cultures. Nat Protoc. 2018;13:2062-2085 pubmed 出版商 |
Wu M, Zhang D, Bi C, Mi T, Zhu W, Xia L, et al. A Chemical Recipe for Generation of Clinical-Grade Striatal Neurons from hESCs. Stem Cell Reports. 2018;11:635-650 pubmed 出版商 |
van den Hurk M, Erwin J, Yeo G, Gage F, Bardy C. Patch-Seq Protocol to Analyze the Electrophysiology, Morphology and Transcriptome of Whole Single Neurons Derived From Human Pluripotent Stem Cells. Front Mol Neurosci. 2018;11:261 pubmed 出版商 |
Zhang W, Wan H, Feng G, Qu J, Wang J, Jing Y, et al. SIRT6 deficiency results in developmental retardation in cynomolgus monkeys. Nature. 2018;560:661-665 pubmed 出版商 |
Terheyden Keighley D, Zhang X, Brand Saberi B, Theiss C. CXCR4/SDF1 signalling promotes sensory neuron clustering in vitro. Biol Open. 2018;7: pubmed 出版商 |
Kumamaru H, Kadoya K, Adler A, Takashima Y, Graham L, Coppola G, et al. Generation and post-injury integration of human spinal cord neural stem cells. Nat Methods. 2018;15:723-731 pubmed 出版商 |
Zhong Q, Laco F, Liao M, Woo T, Oh S, Chai C. Influencing the Fate of Cardiac and Neural Stem Cell Differentiation Using Small Molecule Inhibitors of ALK5. Stem Cells Transl Med. 2018;7:709-720 pubmed 出版商 |
Hock E, Maniecka Z, Hruska Plochan M, Reber S, Laferrière F, Sahadevan M K S, et al. Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function. Cell Rep. 2018;24:987-1000.e7 pubmed 出版商 |
Mizuno G, Wang Y, Shi G, Wang Y, Sun J, Papadopoulos S, et al. Aberrant Calcium Signaling in Astrocytes Inhibits Neuronal Excitability in a Human Down Syndrome Stem Cell Model. Cell Rep. 2018;24:355-365 pubmed 出版商 |
Lee S, Oh Y, Lü Y, Kim W, Yoo A. MicroRNAs Overcome Cell Fate Barrier by Reducing EZH2-Controlled REST Stability during Neuronal Conversion of Human Adult Fibroblasts. Dev Cell. 2018;46:73-84.e7 pubmed 出版商 |
Herrmann M, Anders S, Straub R, Jenei Lanzl Z. TNF inhibits catecholamine production from induced sympathetic neuron-like cells in rheumatoid arthritis and osteoarthritis in vitro. Sci Rep. 2018;8:9645 pubmed 出版商 |
Wang B, Joo J, Mount R, Teubner B, Krenzer A, Ward A, et al. The COPII cargo adapter SEC24C is essential for neuronal homeostasis. J Clin Invest. 2018;128:3319-3332 pubmed 出版商 |
Zhang B, He Y, Xu Y, Mo F, Mi T, Shen Q, et al. Differential antiviral immunity to Japanese encephalitis virus in developing cortical organoids. Cell Death Dis. 2018;9:719 pubmed 出版商 |
Wang Y, Zhu W, Wu M, Wu Y, Liu Z, Liang L, et al. Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease. Stem Cell Reports. 2018;11:171-182 pubmed 出版商 |
Ludtmann M, Angelova P, Horrocks M, Choi M, Rodrigues M, Baev A, et al. α-synuclein oligomers interact with ATP synthase and open the permeability transition pore in Parkinson's disease. Nat Commun. 2018;9:2293 pubmed 出版商 |
Ishihara J, Ishihara A, Fukunaga K, Sasaki K, White M, Briquez P, et al. Laminin heparin-binding peptides bind to several growth factors and enhance diabetic wound healing. Nat Commun. 2018;9:2163 pubmed 出版商 |
Lin Y, Seo J, Gao F, Feldman H, Wen H, Penney J, et al. APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer's Disease Phenotypes in Human iPSC-Derived Brain Cell Types. Neuron. 2018;98:1141-1154.e7 pubmed 出版商 |
Fong L, Yang M, Dos Santos Chaves R, Reyna S, Langness V, Woodruff G, et al. Full-length amyloid precursor protein regulates lipoprotein metabolism and amyloid-β clearance in human astrocytes. J Biol Chem. 2018;293:11341-11357 pubmed 出版商 |
Gonçalves I, Brecht J, Thelen M, Rehorst W, Peters M, Lee H, et al. Neuronal activity regulates DROSHA via autophagy in spinal muscular atrophy. Sci Rep. 2018;8:7907 pubmed 出版商 |
Nzou G, Wicks R, Wicks E, Seale S, Sane C, Chen A, et al. Human Cortex Spheroid with a Functional Blood Brain Barrier for High-Throughput Neurotoxicity Screening and Disease Modeling. Sci Rep. 2018;8:7413 pubmed 出版商 |
Merlo S, Spampinato S, Beneventano M, Sortino M. The contribution of microglia to early synaptic compensatory responses that precede β-amyloid-induced neuronal death. Sci Rep. 2018;8:7297 pubmed 出版商 |
Fan J, Lee H, Lee W, Lin C, Hsu C, Hsieh C, et al. Potential role of CBX7 in regulating pluripotency of adult human pluripotent-like olfactory stem cells in stroke model. Cell Death Dis. 2018;9:502 pubmed 出版商 |
Zhang Q, Nguyen P, Shi S, Burrell J, Cullen D, Le A. 3D bio-printed scaffold-free nerve constructs with human gingiva-derived mesenchymal stem cells promote rat facial nerve regeneration. Sci Rep. 2018;8:6634 pubmed 出版商 |
Kim J, Lee J, Hwang H, Lee D, Park C, Jung S, et al. Wnt signal activation induces midbrain specification through direct binding of the beta-catenin/TCF4 complex to the EN1 promoter in human pluripotent stem cells. Exp Mol Med. 2018;50:24 pubmed 出版商 |
Srikanth P, Lagomarsino V, Muratore C, Ryu S, He A, Taylor W, et al. Shared effects of DISC1 disruption and elevated WNT signaling in human cerebral organoids. Transl Psychiatry. 2018;8:77 pubmed 出版商 |
Adil M, Gaj T, Rao A, Kulkarni R, Fuentes C, Ramadoss G, et al. hPSC-Derived Striatal Cells Generated Using a Scalable 3D Hydrogel Promote Recovery in a Huntington Disease Mouse Model. Stem Cell Reports. 2018;10:1481-1491 pubmed 出版商 |
Fröhlich D, Suchowerska A, Voss C, He R, Wolvetang E, von Jonquieres G, et al. Expression Pattern of the Aspartyl-tRNA Synthetase DARS in the Human Brain. Front Mol Neurosci. 2018;11:81 pubmed 出版商 |
Hwang I, Cao D, Na Y, Kim D, Zhang T, Yao J, et al. Far Upstream Element-Binding Protein 1 Regulates LSD1 Alternative Splicing to Promote Terminal Differentiation of Neural Progenitors. Stem Cell Reports. 2018;10:1208-1221 pubmed 出版商 |
Sarin S, ZUNIGA SANCHEZ E, Kurmangaliyev Y, Cousins H, Patel M, Hernandez J, et al. Role for Wnt Signaling in Retinal Neuropil Development: Analysis via RNA-Seq and In Vivo Somatic CRISPR Mutagenesis. Neuron. 2018;98:109-126.e8 pubmed 出版商 |
Sato C, Barthélemy N, Mawuenyega K, Patterson B, Gordon B, Jockel Balsarotti J, et al. Tau Kinetics in Neurons and the Human Central Nervous System. Neuron. 2018;97:1284-1298.e7 pubmed 出版商 |
Konermann S, Lotfy P, Brideau N, Oki J, Shokhirev M, Hsu P. Transcriptome Engineering with RNA-Targeting Type VI-D CRISPR Effectors. Cell. 2018;173:665-676.e14 pubmed 出版商 |
Saez I, Koyuncu S, Gutiérrez García R, Dieterich C, Vilchez D. Insights into the ubiquitin-proteasome system of human embryonic stem cells. Sci Rep. 2018;8:4092 pubmed 出版商 |
Qian X, Jacob F, Song M, Nguyen H, Song H, Ming G. Generation of human brain region-specific organoids using a miniaturized spinning bioreactor. Nat Protoc. 2018;13:565-580 pubmed 出版商 |
Kogut I, McCarthy S, Pavlova M, Astling D, Chen X, Jakimenko A, et al. High-efficiency RNA-based reprogramming of human primary fibroblasts. Nat Commun. 2018;9:745 pubmed 出版商 |
Shim M, Kim K, Bu J, Nam H, Jeong S, Park T, et al. Elevated intracellular cAMP exacerbates vulnerability to oxidative stress in optic nerve head astrocytes. Cell Death Dis. 2018;9:285 pubmed 出版商 |
Birger A, Ottolenghi M, Perez L, Reubinoff B, Behar O. ALS-related human cortical and motor neurons survival is differentially affected by Sema3A. Cell Death Dis. 2018;9:256 pubmed 出版商 |
Jacko M, Weyn Vanhentenryck S, Smerdon J, Yan R, Feng H, Williams D, et al. Rbfox Splicing Factors Promote Neuronal Maturation and Axon Initial Segment Assembly. Neuron. 2018;97:853-868.e6 pubmed 出版商 |
Martos S, Li T, Ramos R, Lou D, Dai H, Xu J, et al. Two approaches reveal a new paradigm of 'switchable or genetics-influenced allele-specific DNA methylation' with potential in human disease. Cell Discov. 2017;3:17038 pubmed 出版商 |
Su Z, Zhang Y, Liao B, Zhong X, Chen X, Wang H, et al. Antagonism between the transcription factors NANOG and OTX2 specifies rostral or caudal cell fate during neural patterning transition. J Biol Chem. 2018;293:4445-4455 pubmed 出版商 |
Russell O, Fruh I, Rai P, Marcellin D, Doll T, Reeve A, et al. Preferential amplification of a human mitochondrial DNA deletion in vitro and in vivo. Sci Rep. 2018;8:1799 pubmed 出版商 |
Ackerman S, Luo R, Poitelon Y, Mogha A, Harty B, D Rozario M, et al. GPR56/ADGRG1 regulates development and maintenance of peripheral myelin. J Exp Med. 2018;215:941-961 pubmed 出版商 |
Alshawaf A, Viventi S, Qiu W, D Abaco G, Nayagam B, Erlichster M, et al. Phenotypic and Functional Characterization of Peripheral Sensory Neurons derived from Human Embryonic Stem Cells. Sci Rep. 2018;8:603 pubmed 出版商 |
de la Torre Ubieta L, Stein J, Won H, Opland C, Liang D, Lu D, et al. The Dynamic Landscape of Open Chromatin during Human Cortical Neurogenesis. Cell. 2018;172:289-304.e18 pubmed 出版商 |
Hoffman G, Hartley B, Flaherty E, Ladran I, Gochman P, Ruderfer D, et al. Transcriptional signatures of schizophrenia in hiPSC-derived NPCs and neurons are concordant with post-mortem adult brains. Nat Commun. 2017;8:2225 pubmed 出版商 |
Lin J, Mironova Y, Shrager P, Giger R. LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair. elife. 2017;6: pubmed 出版商 |
Parrini M, Ghezzi D, Deidda G, Medrihan L, Castroflorio E, Alberti M, et al. Aerobic exercise and a BDNF-mimetic therapy rescue learning and memory in a mouse model of Down syndrome. Sci Rep. 2017;7:16825 pubmed 出版商 |
Muratore C, Zhou C, Liao M, Fernandez M, Taylor W, Lagomarsino V, et al. Cell-type Dependent Alzheimer's Disease Phenotypes: Probing the Biology of Selective Neuronal Vulnerability. Stem Cell Reports. 2017;9:1868-1884 pubmed 出版商 |
Oksanen M, Petersen A, Naumenko N, Puttonen K, Lehtonen S, Gubert Olivé M, et al. PSEN1 Mutant iPSC-Derived Model Reveals Severe Astrocyte Pathology in Alzheimer's Disease. Stem Cell Reports. 2017;9:1885-1897 pubmed 出版商 |
Ju Lee H, Bartsch D, Xiao C, Guerrero S, Ahuja G, Schindler C, et al. A post-transcriptional program coordinated by CSDE1 prevents intrinsic neural differentiation of human embryonic stem cells. Nat Commun. 2017;8:1456 pubmed 出版商 |
Klapper S, Sauter E, Swiersy A, Hyman M, Bamann C, Bamberg E, et al. On-demand optogenetic activation of human stem-cell-derived neurons. Sci Rep. 2017;7:14450 pubmed 出版商 |
Iribar H, Pérez López V, Etxaniz U, Gutiérrez Rivera A, Izeta A. Schwann Cells in the Ventral Dermis Do Not Derive from Myf5-Expressing Precursors. Stem Cell Reports. 2017;9:1477-1487 pubmed 出版商 |
Farhy Tselnicker I, van Casteren A, Lee A, Chang V, Aricescu A, Allen N. Astrocyte-Secreted Glypican 4 Regulates Release of Neuronal Pentraxin 1 from Axons to Induce Functional Synapse Formation. Neuron. 2017;96:428-445.e13 pubmed 出版商 |
Pease Raissi S, Pazyra Murphy M, Li Y, Wachter F, Fukuda Y, Fenstermacher S, et al. Paclitaxel Reduces Axonal Bclw to Initiate IP3R1-Dependent Axon Degeneration. Neuron. 2017;96:373-386.e6 pubmed 出版商 |
Guo W, Naujock M, Fumagalli L, Vandoorne T, Baatsen P, Boon R, et al. HDAC6 inhibition reverses axonal transport defects in motor neurons derived from FUS-ALS patients. Nat Commun. 2017;8:861 pubmed 出版商 |
Wang C, Ward M, Chen R, Liu K, Tracy T, Chen X, et al. Scalable Production of iPSC-Derived Human Neurons to Identify Tau-Lowering Compounds by High-Content Screening. Stem Cell Reports. 2017;9:1221-1233 pubmed 出版商 |
Kang S, Chen X, Gong S, Yu P, Yau S, Su Z, et al. Characteristic analyses of a neural differentiation model from iPSC-derived neuron according to morphology, physiology, and global gene expression pattern. Sci Rep. 2017;7:12233 pubmed 出版商 |
Ruderisch N, Schlatter D, Kuglstatter A, Guba W, Huber S, Cusulin C, et al. Potent and Selective BACE-1 Peptide Inhibitors Lower Brain A? Levels Mediated by Brain Shuttle Transport. EBioMedicine. 2017;24:76-92 pubmed 出版商 |
Pignataro D, Francia S, Zanetta F, Brenna G, Brandini S, Olivieri A, et al. A missense MT-ND5 mutation in differentiated Parkinson Disease cytoplasmic hybrid induces ROS-dependent DNA Damage Response amplified by DROSHA. Sci Rep. 2017;7:9528 pubmed 出版商 |
Saadipour K, MacLean M, Pirkle S, Ali S, Lopez Redondo M, Stokes D, et al. The transmembrane domain of the p75 neurotrophin receptor stimulates phosphorylation of the TrkB tyrosine kinase receptor. J Biol Chem. 2017;292:16594-16604 pubmed 出版商 |
Sloan S, Darmanis S, Huber N, Khan T, Birey F, Caneda C, et al. Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 2017;95:779-790.e6 pubmed 出版商 |
Tripathi P, Rodríguez Muela N, Klim J, de Boer A, Agrawal S, Sandoe J, et al. Reactive Astrocytes Promote ALS-like Degeneration and Intracellular Protein Aggregation in Human Motor Neurons by Disrupting Autophagy through TGF-β1. Stem Cell Reports. 2017;9:667-680 pubmed 出版商 |
Peng T, Chanthaphavong R, Sun S, Trigilio J, Phasouk K, Jin L, et al. Keratinocytes produce IL-17c to protect peripheral nervous systems during human HSV-2 reactivation. J Exp Med. 2017;214:2315-2329 pubmed 出版商 |
Welsbie D, Mitchell K, Jaskula Ranga V, Sluch V, Yang Z, Kim J, et al. Enhanced Functional Genomic Screening Identifies Novel Mediators of Dual Leucine Zipper Kinase-Dependent Injury Signaling in Neurons. Neuron. 2017;94:1142-1154.e6 pubmed 出版商 |
Birey F, Andersen J, Makinson C, Islam S, Wei W, Huber N, et al. Assembly of functionally integrated human forebrain spheroids. Nature. 2017;545:54-59 pubmed 出版商 |
Monzel A, Smits L, Hemmer K, Hachi S, Moreno E, van Wuellen T, et al. Derivation of Human Midbrain-Specific Organoids from Neuroepithelial Stem Cells. Stem Cell Reports. 2017;8:1144-1154 pubmed 出版商 |
Wang T, Zhang J, Zhu J, Lian H, Yuan H, Gao M, et al. Expression profiles and function analysis of microRNAs in postovulatory aging mouse oocytes. Aging (Albany NY). 2017;9:1186-1201 pubmed 出版商 |
Grima J, Daigle J, Arbez N, Cunningham K, Zhang K, Ochaba J, et al. Mutant Huntingtin Disrupts the Nuclear Pore Complex. Neuron. 2017;94:93-107.e6 pubmed 出版商 |
Xie M, Li M, Zhou J, Ding X, Shao Y, Jing J, et al. Brain-derived neurotrophic factor promotes human granulosa-like tumor cell steroidogenesis and proliferation by activating the FSH receptor-mediated signaling pathway. Sci Rep. 2017;7:180 pubmed 出版商 |
Emperador Melero J, Nadadhur A, Schut D, Weering J, Heine V, Toonen R, et al. Differential Maturation of the Two Regulated Secretory Pathways in Human iPSC-Derived Neurons. Stem Cell Reports. 2017;8:659-672 pubmed 出版商 |
Sternfeld M, Hinckley C, Moore N, Pankratz M, Hilde K, Driscoll S, et al. Speed and segmentation control mechanisms characterized in rhythmically-active circuits created from spinal neurons produced from genetically-tagged embryonic stem cells. elife. 2017;6: pubmed 出版商 |
Gimeno M, Fuertes F, Barcala Tabarrozzi A, Attorressi A, Cucchiani R, Corrales L, et al. Pluripotent Nontumorigenic Adipose Tissue-Derived Muse Cells have Immunomodulatory Capacity Mediated by Transforming Growth Factor-β1. Stem Cells Transl Med. 2017;6:161-173 pubmed 出版商 |
Mazzara P, Massimino L, Pellegatta M, Ronchi G, Ricca A, Iannielli A, et al. Two factor-based reprogramming of rodent and human fibroblasts into Schwann cells. Nat Commun. 2017;8:14088 pubmed 出版商 |
Noormohammadi A, Khodakarami A, Gutiérrez García R, Lee H, Koyuncu S, König T, et al. Somatic increase of CCT8 mimics proteostasis of human pluripotent stem cells and extends C. elegans lifespan. Nat Commun. 2016;7:13649 pubmed 出版商 |
Rubio A, Luoni M, Giannelli S, Radice I, Iannielli A, Cancellieri C, et al. Rapid and efficient CRISPR/Cas9 gene inactivation in human neurons during human pluripotent stem cell differentiation and direct reprogramming. Sci Rep. 2016;6:37540 pubmed 出版商 |
Sugeno N, Jäckel S, Voigt A, Wassouf Z, Schulze Hentrich J, Kahle P. α-Synuclein enhances histone H3 lysine-9 dimethylation and H3K9me2-dependent transcriptional responses. Sci Rep. 2016;6:36328 pubmed 出版商 |
Shim M, Takihara Y, Kim K, Iwata T, Yue B, Inatani M, et al. Mitochondrial pathogenic mechanism and degradation in optineurin E50K mutation-mediated retinal ganglion cell degeneration. Sci Rep. 2016;6:33830 pubmed 出版商 |
Nishioka H, Tooi N, Isobe T, Nakatsuji N, Aiba K. BMS-708163 and Nilotinib restore synaptic dysfunction in human embryonic stem cell-derived Alzheimer's disease models. Sci Rep. 2016;6:33427 pubmed 出版商 |
Borgs L, Peyre E, Alix P, Hanon K, Grobarczyk B, Godin J, et al. Dopaminergic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Sci Rep. 2016;6:33377 pubmed 出版商 |
Gennet N, Tamburini C, Nan X, Li M. FolR1: a novel cell surface marker for isolating midbrain dopamine neural progenitors and nascent dopamine neurons. Sci Rep. 2016;6:32488 pubmed 出版商 |
Guo X, Sun X, Hu D, Wang Y, Fujioka H, Vyas R, et al. VCP recruitment to mitochondria causes mitophagy impairment and neurodegeneration in models of Huntington's disease. Nat Commun. 2016;7:12646 pubmed 出版商 |
Redmond S, Mei F, Eshed Eisenbach Y, Osso L, Leshkowitz D, Shen Y, et al. Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination. Neuron. 2016;91:824-836 pubmed 出版商 |
Kapeli K, Pratt G, Vu A, Hutt K, Martinez F, Sundararaman B, et al. Distinct and shared functions of ALS-associated proteins TDP-43, FUS and TAF15 revealed by multisystem analyses. Nat Commun. 2016;7:12143 pubmed 出版商 |
Wright T, Gillespie L, O Leary S, Needham K. Firing frequency and entrainment maintained in primary auditory neurons in the presence of combined BDNF and NT3. Sci Rep. 2016;6:28584 pubmed 出版商 |
Ulivieri C, Savino M, Luccarini I, Fanigliulo E, Aldinucci A, Bonechi E, et al. The Adaptor Protein Rai/ShcC Promotes Astrocyte-Dependent Inflammation during Experimental Autoimmune Encephalomyelitis. J Immunol. 2016;197:480-90 pubmed 出版商 |
Rhim J, Luo X, Gao D, Xu X, Zhou T, Li F, et al. Cell type-dependent Erk-Akt pathway crosstalk regulates the proliferation of fetal neural progenitor cells. Sci Rep. 2016;6:26547 pubmed 出版商 |
Allodi I, Comley L, Nichterwitz S, Nizzardo M, Simone C, Benitez J, et al. Differential neuronal vulnerability identifies IGF-2 as a protective factor in ALS. Sci Rep. 2016;6:25960 pubmed 出版商 |
He J, Zhou R, Wu Z, Carrasco M, Kurshan P, Farley J, et al. Prevalent presence of periodic actin-spectrin-based membrane skeleton in a broad range of neuronal cell types and animal species. Proc Natl Acad Sci U S A. 2016;113:6029-34 pubmed 出版商 |
Vagaska B, New S, Alvarez González C, D Acquisto F, Gomez S, Bulstrode N, et al. MHC-class-II are expressed in a subpopulation of human neural stem cells in vitro in an IFNγ-independent fashion and during development. Sci Rep. 2016;6:24251 pubmed 出版商 |
Zhang W, Ross P, Tu Y, Wang Y, Beggs S, Sengar A, et al. Fyn Kinase regulates GluN2B subunit-dominant NMDA receptors in human induced pluripotent stem cell-derived neurons. Sci Rep. 2016;6:23837 pubmed 出版商 |
Smedowski A, Liu X, Pietrucha Dutczak M, Matuszek I, Varjosalo M, Lewin Kowalik J. Predegenerated Schwann cells--a novel prospect for cell therapy for glaucoma: neuroprotection, neuroregeneration and neuroplasticity. Sci Rep. 2016;6:23187 pubmed 出版商 |
Patzke C, Acuna C, Giam L, Wernig M, Südhof T. Conditional deletion of L1CAM in human neurons impairs both axonal and dendritic arborization and action potential generation. J Exp Med. 2016;213:499-515 pubmed 出版商 |
Carlson A, Bennett N, Francis N, Halikere A, Clarke S, Moore J, et al. Generation and transplantation of reprogrammed human neurons in the brain using 3D microtopographic scaffolds. Nat Commun. 2016;7:10862 pubmed 出版商 |
Remenyi J, Bajan S, Fuller Pace F, Arthur J, Hutvagner G. The loop structure and the RNA helicase p72/DDX17 influence the processing efficiency of the mice miR-132. Sci Rep. 2016;6:22848 pubmed 出版商 |
Wang L, Li X, Huang W, Zhou T, Wang H, Lin A, et al. TGFβ signaling regulates the choice between pluripotent and neural fates during reprogramming of human urine derived cells. Sci Rep. 2016;6:22484 pubmed 出版商 |
Nizzardo M, Simone C, Rizzo F, Ulzi G, Ramirez A, Rizzuti M, et al. Morpholino-mediated SOD1 reduction ameliorates an amyotrophic lateral sclerosis disease phenotype. Sci Rep. 2016;6:21301 pubmed 出版商 |
Morgado A, Rodrigues C, Solá S. MicroRNA-145 Regulates Neural Stem Cell Differentiation Through the Sox2-Lin28/let-7 Signaling Pathway. Stem Cells. 2016;34:1386-95 pubmed 出版商 |
Venugopalan P, Wang Y, Nguyen T, Huang A, Muller K, Goldberg J. Transplanted neurons integrate into adult retinas and respond to light. Nat Commun. 2016;7:10472 pubmed 出版商 |
Wang P, Du C, Chen F, Li C, Yu Y, Han T, et al. BDNF contributes to IBS-like colonic hypersensitivity via activating the enteroglia-nerve unit. Sci Rep. 2016;6:20320 pubmed 出版商 |
Wang H, Hu L, Liu C, Su Z, Wang L, Pan G, et al. 5-HT2 receptors mediate functional modulation of GABAa receptors and inhibitory synaptic transmissions in human iPS-derived neurons. Sci Rep. 2016;6:20033 pubmed 出版商 |
Cohen M, Wert K, Goldmann J, Markoulaki S, Buganim Y, Fu D, et al. Human neural crest cells contribute to coat pigmentation in interspecies chimeras after in utero injection into mouse embryos. Proc Natl Acad Sci U S A. 2016;113:1570-5 pubmed 出版商 |
Iyer N, Huettner J, Butts J, Brown C, Sakiyama Elbert S. Generation of highly enriched V2a interneurons from mouse embryonic stem cells. Exp Neurol. 2016;277:305-316 pubmed 出版商 |
Smith F, Davis R. Organ of Corti explants direct tonotopically graded morphology of spiral ganglion neurons in vitro. J Comp Neurol. 2016;524:2182-207 pubmed 出版商 |
Jiang H, Xu Z, Zhong P, Ren Y, Liang G, Schilling H, et al. Cell cycle and p53 gate the direct conversion of human fibroblasts to dopaminergic neurons. Nat Commun. 2015;6:10100 pubmed 出版商 |
Duan S, Yuan G, Liu X, Ren R, Li J, Zhang W, et al. PTEN deficiency reprogrammes human neural stem cells towards a glioblastoma stem cell-like phenotype. Nat Commun. 2015;6:10068 pubmed 出版商 |
Boisvert E, Engle S, Hallowell S, Liu P, Wang Z, Li X. The Specification and Maturation of Nociceptive Neurons from Human Embryonic Stem Cells. Sci Rep. 2015;5:16821 pubmed 出版商 |
Sluch V, Davis C, Ranganathan V, Kerr J, Krick K, Martin R, et al. Differentiation of human ESCs to retinal ganglion cells using a CRISPR engineered reporter cell line. Sci Rep. 2015;5:16595 pubmed 出版商 |
Ng T, Yung J, Choy K, Cao D, Leung C, Cheung H, et al. Transdifferentiation of periodontal ligament-derived stem cells into retinal ganglion-like cells and its microRNA signature. Sci Rep. 2015;5:16429 pubmed 出版商 |
Palm T, Bolognin S, Meiser J, Nickels S, Träger C, Meilenbrock R, et al. Rapid and robust generation of long-term self-renewing human neural stem cells with the ability to generate mature astroglia. Sci Rep. 2015;5:16321 pubmed 出版商 |
Tsenkina Y, Ricard J, Runko E, Quiala Acosta M, Mier J, Liebl D. EphB3 receptors function as dependence receptors to mediate oligodendrocyte cell death following contusive spinal cord injury. Cell Death Dis. 2015;6:e1922 pubmed 出版商 |
Gibbs K, Kalmar B, Sleigh J, Greensmith L, Schiavo G. In vivo imaging of axonal transport in murine motor and sensory neurons. J Neurosci Methods. 2016;257:26-33 pubmed 出版商 |
Fulgenzi G, Tomassoni Ardori F, Babini L, Becker J, Barrick C, Puverel S, et al. BDNF modulates heart contraction force and long-term homeostasis through truncated TrkB.T1 receptor activation. J Cell Biol. 2015;210:1003-12 pubmed |
Prieto G, Snigdha S, Baglietto Vargas D, Smith E, Berchtold N, Tong L, et al. Synapse-specific IL-1 receptor subunit reconfiguration augments vulnerability to IL-1β in the aged hippocampus. Proc Natl Acad Sci U S A. 2015;112:E5078-87 pubmed 出版商 |
Korb E, Herre M, Zucker Scharff I, Darnell R, Allis C. BET protein Brd4 activates transcription in neurons and BET inhibitor Jq1 blocks memory in mice. Nat Neurosci. 2015;18:1464-73 pubmed 出版商 |
Patzke C, Han Y, Covy J, Yi F, Maxeiner S, Wernig M, et al. Analysis of conditional heterozygous STXBP1 mutations in human neurons. J Clin Invest. 2015;125:3560-71 pubmed 出版商 |
Tian C, Li Y, Huang Y, Wang Y, Chen D, Liu J, et al. Selective Generation of Dopaminergic Precursors from Mouse Fibroblasts by Direct Lineage Conversion. Sci Rep. 2015;5:12622 pubmed 出版商 |
Nizzardo M, Simone C, Dametti S, Salani S, Ulzi G, Pagliarani S, et al. Spinal muscular atrophy phenotype is ameliorated in human motor neurons by SMN increase via different novel RNA therapeutic approaches. Sci Rep. 2015;5:11746 pubmed 出版商 |
Bardy C, van den Hurk M, Eames T, Marchand C, Hernandez R, Kellogg M, et al. Neuronal medium that supports basic synaptic functions and activity of human neurons in vitro. Proc Natl Acad Sci U S A. 2015;112:E2725-34 pubmed 出版商 |
Adams K, Rousso D, Umbach J, Novitch B. Foxp1-mediated programming of limb-innervating motor neurons from mouse and human embryonic stem cells. Nat Commun. 2015;6:6778 pubmed 出版商 |
Lippmann E, Williams C, Ruhl D, Estevez Silva M, Chapman E, Coon J, et al. Deterministic HOX patterning in human pluripotent stem cell-derived neuroectoderm. Stem Cell Reports. 2015;4:632-44 pubmed 出版商 |
Nieweg K, Andreyeva A, van Stegen B, Tanriöver G, Gottmann K. Alzheimer's disease-related amyloid-β induces synaptotoxicity in human iPS cell-derived neurons. Cell Death Dis. 2015;6:e1709 pubmed 出版商 |
Li Y, Polak U, Bhalla A, Rozwadowska N, Butler J, Lynch D, et al. Excision of Expanded GAA Repeats Alleviates the Molecular Phenotype of Friedreich's Ataxia. Mol Ther. 2015;23:1055-1065 pubmed 出版商 |
Topol A, Tran N, Brennand K. A guide to generating and using hiPSC derived NPCs for the study of neurological diseases. J Vis Exp. 2015;:e52495 pubmed 出版商 |
La Montanara P, Rusconi L, Locarno A, Forti L, Barbiero I, Tramarin M, et al. Synaptic synthesis, dephosphorylation, and degradation: a novel paradigm for an activity-dependent neuronal control of CDKL5. J Biol Chem. 2015;290:4512-27 pubmed 出版商 |
Lawn S, Krishna N, Pisklakova A, Qu X, Fenstermacher D, Fournier M, et al. Neurotrophin signaling via TrkB and TrkC receptors promotes the growth of brain tumor-initiating cells. J Biol Chem. 2015;290:3814-24 pubmed 出版商 |
Di Angelantonio S, Murana E, Cocco S, Scala F, Bertollini C, Molinari M, et al. A role for intracellular zinc in glioma alteration of neuronal chloride equilibrium. Cell Death Dis. 2014;5:e1501 pubmed 出版商 |
Pathak M, Nourse J, Tran T, Hwe J, Arulmoli J, Le D, et al. Stretch-activated ion channel Piezo1 directs lineage choice in human neural stem cells. Proc Natl Acad Sci U S A. 2014;111:16148-53 pubmed 出版商 |
Ben Shushan E, Feldman E, Reubinoff B. Notch signaling regulates motor neuron differentiation of human embryonic stem cells. Stem Cells. 2015;33:403-15 pubmed 出版商 |
Wang Y, Chakravarty P, Ranes M, Kelly G, Brooks P, Neilan E, et al. Dysregulation of gene expression as a cause of Cockayne syndrome neurological disease. Proc Natl Acad Sci U S A. 2014;111:14454-9 pubmed 出版商 |
Lu L, Zheng L, Si Y, Luo W, Dujardin G, Kwan T, et al. Hu antigen R (HuR) is a positive regulator of the RNA-binding proteins TDP-43 and FUS/TLS: implications for amyotrophic lateral sclerosis. J Biol Chem. 2014;289:31792-804 pubmed 出版商 |
Liu X, Obianyo O, Chan C, Huang J, Xue S, Yang J, et al. Biochemical and biophysical investigation of the brain-derived neurotrophic factor mimetic 7,8-dihydroxyflavone in the binding and activation of the TrkB receptor. J Biol Chem. 2014;289:27571-84 pubmed 出版商 |
Zuchero J. Purification of dorsal root ganglion neurons from rat by immunopanning. Cold Spring Harb Protoc. 2014;2014:826-38 pubmed 出版商 |
Chen C, Jiang P, Xue H, Peterson S, Tran H, McCann A, et al. Role of astroglia in Down's syndrome revealed by patient-derived human-induced pluripotent stem cells. Nat Commun. 2014;5:4430 pubmed 出版商 |
Smith E, Prieto G, Tong L, Sears Kraxberger I, Rice J, Steward O, et al. Rapamycin and interleukin-1? impair brain-derived neurotrophic factor-dependent neuron survival by modulating autophagy. J Biol Chem. 2014;289:20615-29 pubmed |
Potts M, Siu J, Price J, Salinas R, Cho M, Ramos A, et al. Analysis of Mll1 deficiency identifies neurogenic transcriptional modules and Brn4 as a factor for direct astrocyte-to-neuron reprogramming. Neurosurgery. 2014;75:472-82; discussion 482 pubmed 出版商 |
Scardigli R, Capelli P, Vignone D, Brandi R, Ceci M, La Regina F, et al. Neutralization of nerve growth factor impairs proliferation and differentiation of adult neural progenitors in the subventricular zone. Stem Cells. 2014;32:2516-28 pubmed 出版商 |
Kim T, Yao R, Monnell T, Cho J, Vasudevan A, Koh A, et al. Efficient specification of interneurons from human pluripotent stem cells by dorsoventral and rostrocaudal modulation. Stem Cells. 2014;32:1789-804 pubmed 出版商 |
Forsyth P, Krishna N, Lawn S, Valadez J, Qu X, Fenstermacher D, et al. p75 neurotrophin receptor cleavage by ?- and ?-secretases is required for neurotrophin-mediated proliferation of brain tumor-initiating cells. J Biol Chem. 2014;289:8067-85 pubmed 出版商 |
Yelamanchili S, Morsey B, Harrison E, Rennard D, Emanuel K, Thapa I, et al. The evolutionary young miR-1290 favors mitotic exit and differentiation of human neural progenitors through altering the cell cycle proteins. Cell Death Dis. 2014;5:e982 pubmed 出版商 |
Lippmann E, Estevez Silva M, Ashton R. Defined human pluripotent stem cell culture enables highly efficient neuroepithelium derivation without small molecule inhibitors. Stem Cells. 2014;32:1032-42 pubmed 出版商 |
Donato F, Rompani S, Caroni P. Parvalbumin-expressing basket-cell network plasticity induced by experience regulates adult learning. Nature. 2013;504:272-6 pubmed 出版商 |
Su B, Ji Y, Sun X, Liu X, Chen Z. Brain-derived neurotrophic factor (BDNF)-induced mitochondrial motility arrest and presynaptic docking contribute to BDNF-enhanced synaptic transmission. J Biol Chem. 2014;289:1213-26 pubmed 出版商 |
Macas J, Ku M, Nern C, Xu Y, Buhler H, Remke M, et al. Generation of neuronal progenitor cells in response to tumors in the human brain. Stem Cells. 2014;32:244-57 pubmed 出版商 |
Do H, Bruelle C, Tselykh T, Jalonen P, Korhonen L, Lindholm D. Reciprocal regulation of very low density lipoprotein receptors (VLDLRs) in neurons by brain-derived neurotrophic factor (BDNF) and Reelin: involvement of the E3 ligase Mylip/Idol. J Biol Chem. 2013;288:29613-20 pubmed 出版商 |
Lambert W, Xu C, Neubert T, Chao M, Garabedian M, Jeanneteau F. Brain-derived neurotrophic factor signaling rewrites the glucocorticoid transcriptome via glucocorticoid receptor phosphorylation. Mol Cell Biol. 2013;33:3700-14 pubmed 出版商 |
Henle S, Carlstrom L, Cheever T, Henley J. Differential role of PTEN phosphatase in chemotactic growth cone guidance. J Biol Chem. 2013;288:20837-42 pubmed 出版商 |
Zhang Y, Pak C, Han Y, Ahlenius H, Zhang Z, Chanda S, et al. Rapid single-step induction of functional neurons from human pluripotent stem cells. Neuron. 2013;78:785-98 pubmed 出版商 |
Weick J, Held D, Bonadurer G, Doers M, Liu Y, Maguire C, et al. Deficits in human trisomy 21 iPSCs and neurons. Proc Natl Acad Sci U S A. 2013;110:9962-7 pubmed 出版商 |
Sundberg M, Bogetofte H, Lawson T, Jansson J, Smith G, Astradsson A, et al. Improved cell therapy protocols for Parkinson's disease based on differentiation efficiency and safety of hESC-, hiPSC-, and non-human primate iPSC-derived dopaminergic neurons. Stem Cells. 2013;31:1548-62 pubmed 出版商 |
Martino M, Briquez P, Ranga A, Lutolf M, Hubbell J. Heparin-binding domain of fibrin(ogen) binds growth factors and promotes tissue repair when incorporated within a synthetic matrix. Proc Natl Acad Sci U S A. 2013;110:4563-8 pubmed 出版商 |
Shintani Y, Kapoor A, Kaneko M, Smolenski R, D Acquisto F, Coppen S, et al. TLR9 mediates cellular protection by modulating energy metabolism in cardiomyocytes and neurons. Proc Natl Acad Sci U S A. 2013;110:5109-14 pubmed 出版商 |
Grade S, Weng Y, Snapyan M, Kriz J, Malva J, Saghatelyan A. Brain-derived neurotrophic factor promotes vasculature-associated migration of neuronal precursors toward the ischemic striatum. PLoS ONE. 2013;8:e55039 pubmed 出版商 |
Xue Y, Ouyang K, Huang J, Zhou Y, Ouyang H, Li H, et al. Direct conversion of fibroblasts to neurons by reprogramming PTB-regulated microRNA circuits. Cell. 2013;152:82-96 pubmed 出版商 |
Howe E, Cochrane D, Cittelly D, Richer J. miR-200c targets a NF-?B up-regulated TrkB/NTF3 autocrine signaling loop to enhance anoikis sensitivity in triple negative breast cancer. PLoS ONE. 2012;7:e49987 pubmed 出版商 |
Wang Y, Zhang T, Xin J, Li T, Yu H, Li N, et al. Differential involvement of brain-derived neurotrophic factor in reconsolidation and consolidation of conditioned taste aversion memory. PLoS ONE. 2012;7:e49942 pubmed 出版商 |
Kawamura K, Chen Y, Shu Y, Cheng Y, Qiao J, Behr B, et al. Promotion of human early embryonic development and blastocyst outgrowth in vitro using autocrine/paracrine growth factors. PLoS ONE. 2012;7:e49328 pubmed 出版商 |
Dong Q, Ji Y, Cai C, Chen Z. LIM kinase 1 (LIMK1) interacts with tropomyosin-related kinase B (TrkB) and Mediates brain-derived neurotrophic factor (BDNF)-induced axonal elongation. J Biol Chem. 2012;287:41720-31 pubmed 出版商 |
Ai L, Sun C, Zhang L, Zhou S, Chu Z, Qin Y, et al. Inhibition of BDNF in multiple myeloma blocks osteoclastogenesis via down-regulated stroma-derived RANKL expression both in vitro and in vivo. PLoS ONE. 2012;7:e46287 pubmed 出版商 |
Lu P, Wang Y, Graham L, McHale K, Gao M, Wu D, et al. Long-distance growth and connectivity of neural stem cells after severe spinal cord injury. Cell. 2012;150:1264-73 pubmed 出版商 |
Vilchez D, Boyer L, Morantte I, Lutz M, Merkwirth C, Joyce D, et al. Increased proteasome activity in human embryonic stem cells is regulated by PSMD11. Nature. 2012;489:304-8 pubmed 出版商 |
Beck H, Flynn K, Lindenberg K, Schwarz H, Bradke F, Di Giovanni S, et al. Serum Response Factor (SRF)-cofilin-actin signaling axis modulates mitochondrial dynamics. Proc Natl Acad Sci U S A. 2012;109:E2523-32 pubmed |
Kim D, Lee D, Kim H, Yoo J, Jung S, Lim B, et al. Highly pure and expandable PSA-NCAM-positive neural precursors from human ESC and iPSC-derived neural rosettes. PLoS ONE. 2012;7:e39715 pubmed 出版商 |
Giorgetti A, Marchetto M, Li M, Yu D, Fazzina R, Mu Y, et al. Cord blood-derived neuronal cells by ectopic expression of Sox2 and c-Myc. Proc Natl Acad Sci U S A. 2012;109:12556-61 pubmed 出版商 |
Filipovic R, Santhosh Kumar S, Fiondella C, LoTurco J. Increasing doublecortin expression promotes migration of human embryonic stem cell-derived neurons. Stem Cells. 2012;30:1852-62 pubmed 出版商 |
Kapucu F, Tanskanen J, Mikkonen J, Yl xe4 Outinen L, Narkilahti S, Hyttinen J. Burst analysis tool for developing neuronal networks exhibiting highly varying action potential dynamics. Front Comput Neurosci. 2012;6:38 pubmed 出版商 |
Travo C, Gaboyard Niay S, Chabbert C. Plasticity of Scarpa's Ganglion Neurons as a Possible Basis for Functional Restoration within Vestibular Endorgans. Front Neurol. 2012;3:91 pubmed 出版商 |
Park T, Monzo H, Mee E, Bergin P, Teoh H, Montgomery J, et al. Adult human brain neural progenitor cells (NPCs) and fibroblast-like cells have similar properties in vitro but only NPCs differentiate into neurons. PLoS ONE. 2012;7:e37742 pubmed 出版商 |
Hayashi H, Eguchi Y, Fukuchi Nakaishi Y, Takeya M, Nakagata N, Tanaka K, et al. A potential neuroprotective role of apolipoprotein E-containing lipoproteins through low density lipoprotein receptor-related protein 1 in normal tension glaucoma. J Biol Chem. 2012;287:25395-406 pubmed 出版商 |
Abe H, Okazawa M, Nakanishi S. Gene regulation via excitation and BDNF is mediated by induction and phosphorylation of the Etv1 transcription factor in cerebellar granule cells. Proc Natl Acad Sci U S A. 2012;109:8734-9 pubmed 出版商 |
Baeza Raja B, Li P, Le Moan N, Sachs B, Schachtrup C, Davalos D, et al. p75 neurotrophin receptor regulates glucose homeostasis and insulin sensitivity. Proc Natl Acad Sci U S A. 2012;109:5838-43 pubmed 出版商 |
Unterlauft J, Eichler W, Kuhne K, Yang X, Yafai Y, Wiedemann P, et al. Pigment epithelium-derived factor released by Müller glial cells exerts neuroprotective effects on retinal ganglion cells. Neurochem Res. 2012;37:1524-33 pubmed 出版商 |
Di Lieto A, Rantamäki T, Vesa L, Yanpallewar S, Antila H, Lindholm J, et al. The responsiveness of TrkB to BDNF and antidepressant drugs is differentially regulated during mouse development. PLoS ONE. 2012;7:e32869 pubmed 出版商 |
Colombo E, Cordiglieri C, Melli G, Newcombe J, Krumbholz M, Parada L, et al. Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration. J Exp Med. 2012;209:521-35 pubmed 出版商 |
Kurihara D, Yamashita T. Chondroitin sulfate proteoglycans down-regulate spine formation in cortical neurons by targeting tropomyosin-related kinase B (TrkB) protein. J Biol Chem. 2012;287:13822-8 pubmed 出版商 |
Shen J, Ghai K, Sompol P, Liu X, Cao X, Iuvone P, et al. N-acetyl serotonin derivatives as potent neuroprotectants for retinas. Proc Natl Acad Sci U S A. 2012;109:3540-5 pubmed 出版商 |
Lakadamyali M, Babcock H, Bates M, Zhuang X, Lichtman J. 3D multicolor super-resolution imaging offers improved accuracy in neuron tracing. PLoS ONE. 2012;7:e30826 pubmed 出版商 |
Sadan O, Shemesh N, Barzilay R, Dadon Nahum M, Blumenfeld Katzir T, Assaf Y, et al. Mesenchymal stem cells induced to secrete neurotrophic factors attenuate quinolinic acid toxicity: a potential therapy for Huntington's disease. Exp Neurol. 2012;234:417-27 pubmed 出版商 |
Killian R, Flippin J, Herrera C, Almenar Queralt A, Goldstein L. Kinesin light chain 1 suppression impairs human embryonic stem cell neural differentiation and amyloid precursor protein metabolism. PLoS ONE. 2012;7:e29755 pubmed 出版商 |
Jeanneteau F, Lambert W, Ismaili N, Bath K, Lee F, Garabedian M, et al. BDNF and glucocorticoids regulate corticotrophin-releasing hormone (CRH) homeostasis in the hypothalamus. Proc Natl Acad Sci U S A. 2012;109:1305-10 pubmed 出版商 |
Li X, Yan J, Huang S, Zhao L, Wang J, Chen Z. Identification of a key motif that determines the differential surface levels of RET and TrkB tyrosine kinase receptors and controls depolarization enhanced RET surface insertion. J Biol Chem. 2012;287:1932-45 pubmed 出版商 |
Carlstrom L, Hines J, Henle S, Henley J. Bidirectional remodeling of ?1-integrin adhesions during chemotropic regulation of nerve growth. BMC Biol. 2011;9:82 pubmed 出版商 |
Han L, Wen Z, Lynn R, Baudet M, Holt C, Sasaki Y, et al. Regulation of chemotropic guidance of nerve growth cones by microRNA. Mol Brain. 2011;4:40 pubmed 出版商 |
Swanger S, Yao X, Gross C, Bassell G. Automated 4D analysis of dendritic spine morphology: applications to stimulus-induced spine remodeling and pharmacological rescue in a disease model. Mol Brain. 2011;4:38 pubmed 出版商 |
Labeed F, Lu J, Mulhall H, Marchenko S, Hoettges K, Estrada L, et al. Biophysical characteristics reveal neural stem cell differentiation potential. PLoS ONE. 2011;6:e25458 pubmed 出版商 |
Foo L, Allen N, Bushong E, Ventura P, Chung W, Zhou L, et al. Development of a method for the purification and culture of rodent astrocytes. Neuron. 2011;71:799-811 pubmed 出版商 |
Miranda C, Teixeira C, Liz M, Sousa V, Franquinho F, Forte G, et al. Systemic delivery of bone marrow-derived mesenchymal stromal cells diminishes neuropathology in a mouse model of Krabbe's disease. Stem Cells. 2011;29:1738-51 pubmed 出版商 |
Fujita Y, Takashima R, Endo S, Takai T, Yamashita T. The p75 receptor mediates axon growth inhibition through an association with PIR-B. Cell Death Dis. 2011;2:e198 pubmed 出版商 |
Devine M, Ryten M, Vodicka P, Thomson A, Burdon T, Houlden H, et al. Parkinson's disease induced pluripotent stem cells with triplication of the α-synuclein locus. Nat Commun. 2011;2:440 pubmed 出版商 |
Koehler K, Tropel P, Theile J, Kondo T, Cummins T, Viville S, et al. Extended passaging increases the efficiency of neural differentiation from induced pluripotent stem cells. BMC Neurosci. 2011;12:82 pubmed 出版商 |
Babu H, Claasen J, Kannan S, Rünker A, Palmer T, Kempermann G. A protocol for isolation and enriched monolayer cultivation of neural precursor cells from mouse dentate gyrus. Front Neurosci. 2011;5:89 pubmed 出版商 |
Stacpoole S, Bilican B, Webber D, Luzhynskaya A, He X, Compston A, et al. Efficient derivation of NPCs, spinal motor neurons and midbrain dopaminergic neurons from hESCs at 3% oxygen. Nat Protoc. 2011;6:1229-40 pubmed 出版商 |
Yoo A, Sun A, Li L, Shcheglovitov A, Portmann T, Li Y, et al. MicroRNA-mediated conversion of human fibroblasts to neurons. Nature. 2011;476:228-31 pubmed 出版商 |
Cunha C, Panseri S, Villa O, Silva D, Gelain F. 3D culture of adult mouse neural stem cells within functionalized self-assembling peptide scaffolds. Int J Nanomedicine. 2011;6:943-55 pubmed 出版商 |
Mitne Neto M, Machado Costa M, Marchetto M, Bengtson M, Joazeiro C, Tsuda H, et al. Downregulation of VAPB expression in motor neurons derived from induced pluripotent stem cells of ALS8 patients. Hum Mol Genet. 2011;20:3642-52 pubmed 出版商 |
Ahmed Z, Kalinski H, Berry M, Almasieh M, Ashush H, Slager N, et al. Ocular neuroprotection by siRNA targeting caspase-2. Cell Death Dis. 2011;2:e173 pubmed 出版商 |
Rantamäki T, Vesa L, Antila H, Di Lieto A, Tammela P, Schmitt A, et al. Antidepressant drugs transactivate TrkB neurotrophin receptors in the adult rodent brain independently of BDNF and monoamine transporter blockade. PLoS ONE. 2011;6:e20567 pubmed 出版商 |
Deleidi M, Hargus G, Hallett P, Osborn T, Isacson O. Development of histocompatible primate-induced pluripotent stem cells for neural transplantation. Stem Cells. 2011;29:1052-63 pubmed 出版商 |
Cohen Kupiec R, Pasmanik Chor M, Oron Karni V, Weil M. Effects of IKAP/hELP1 deficiency on gene expression in differentiating neuroblastoma cells: implications for familial dysautonomia. PLoS ONE. 2011;6:e19147 pubmed 出版商 |
Wong R, Ibrahim A, Fong H, Thompson N, Lock L, Donovan P. L1TD1 is a marker for undifferentiated human embryonic stem cells. PLoS ONE. 2011;6:e19355 pubmed 出版商 |
Cazorla M, Premont J, Mann A, Girard N, Kellendonk C, Rognan D. Identification of a low-molecular weight TrkB antagonist with anxiolytic and antidepressant activity in mice. J Clin Invest. 2011;121:1846-57 pubmed 出版商 |
Isomura R, Kitajima K, Sato C. Structural and functional impairments of polysialic acid by a mutated polysialyltransferase found in schizophrenia. J Biol Chem. 2011;286:21535-45 pubmed 出版商 |
Liu S, Liu S, Wang X, Zhou J, Cao Y, Wang F, et al. The PI3K-Akt pathway inhibits senescence and promotes self-renewal of human skin-derived precursors in vitro. Aging Cell. 2011;10:661-74 pubmed 出版商 |
Yuan S, Martin J, Elia J, Flippin J, Paramban R, Hefferan M, et al. Cell-surface marker signatures for the isolation of neural stem cells, glia and neurons derived from human pluripotent stem cells. PLoS ONE. 2011;6:e17540 pubmed 出版商 |
Geiger T, Song J, Rosado A, Peeper D. Functional characterization of human cancer-derived TRKB mutations. PLoS ONE. 2011;6:e16871 pubmed 出版商 |
Cheung A, Horvath L, Grafodatskaya D, Pasceri P, Weksberg R, Hotta A, et al. Isolation of MECP2-null Rett Syndrome patient hiPS cells and isogenic controls through X-chromosome inactivation. Hum Mol Genet. 2011;20:2103-15 pubmed 出版商 |
Gomez Sanchez J, Delgado Esteban M, Rodriguez Hernandez I, Sobrino T, Perez de la Ossa N, Reverte S, et al. The human Tp53 Arg72Pro polymorphism explains different functional prognosis in stroke. J Exp Med. 2011;208:429-37 pubmed 出版商 |
Souza T, Rodrigues D, Passaes C, Barreto de Souza V, Aguiar R, Temerozo J, et al. The nerve growth factor reduces APOBEC3G synthesis and enhances HIV-1 transcription and replication in human primary macrophages. Blood. 2011;117:2944-52 pubmed 出版商 |
Zhang X, Li Liu D, Chiang S, Choy K, Pang C, Lam D, et al. Immunopanning purification and long-term culture of human retinal ganglion cells. Mol Vis. 2010;16:2867-72 pubmed |
Ruiz S, Brennand K, Panopoulos A, Herrerias A, Gage F, Izpisua Belmonte J. High-efficient generation of induced pluripotent stem cells from human astrocytes. PLoS ONE. 2010;5:e15526 pubmed 出版商 |
Rivera Arconada I, Benedet T, Roza C, Torres B, Barrio J, Krzyzanowska A, et al. DREAM regulates BDNF-dependent spinal sensitization. Mol Pain. 2010;6:95 pubmed 出版商 |
Garcia O, Torres M, Helguera P, Coskun P, Busciglio J. A role for thrombospondin-1 deficits in astrocyte-mediated spine and synaptic pathology in Down's syndrome. PLoS ONE. 2010;5:e14200 pubmed 出版商 |
Barkis W, Ford K, Feller M. Non-cell-autonomous factor induces the transition from excitatory to inhibitory GABA signaling in retina independent of activity. Proc Natl Acad Sci U S A. 2010;107:22302-7 pubmed 出版商 |
Zhang N, An M, Montoro D, Ellerby L. Characterization of Human Huntington's Disease Cell Model from Induced Pluripotent Stem Cells. PLoS Curr. 2010;2:RRN1193 pubmed 出版商 |
Hargus G, Cooper O, Deleidi M, Levy A, Lee K, Marlow E, et al. Differentiated Parkinson patient-derived induced pluripotent stem cells grow in the adult rodent brain and reduce motor asymmetry in Parkinsonian rats. Proc Natl Acad Sci U S A. 2010;107:15921-6 pubmed 出版商 |
Zeng H, Guo M, Martins Taylor K, Wang X, Zhang Z, Park J, et al. Specification of region-specific neurons including forebrain glutamatergic neurons from human induced pluripotent stem cells. PLoS ONE. 2010;5:e11853 pubmed 出版商 |
Mäkelä J, Koivuniemi R, Korhonen L, Lindholm D. Interferon-gamma produced by microglia and the neuropeptide PACAP have opposite effects on the viability of neural progenitor cells. PLoS ONE. 2010;5:e11091 pubmed 出版商 |
Wu K, Zhou X, Luo Z. Geranylgeranyltransferase I is essential for dendritic development of cerebellar Purkinje cells. Mol Brain. 2010;3:18 pubmed 出版商 |
Halterman M, Gill M, Dejesus C, Ogihara M, Schor N, Federoff H. The endoplasmic reticulum stress response factor CHOP-10 protects against hypoxia-induced neuronal death. J Biol Chem. 2010;285:21329-40 pubmed 出版商 |
Gines S, Paoletti P, Alberch J. Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression. J Biol Chem. 2010;285:21537-48 pubmed 出版商 |
Fallini C, Bassell G, Rossoll W. High-efficiency transfection of cultured primary motor neurons to study protein localization, trafficking, and function. Mol Neurodegener. 2010;5:17 pubmed 出版商 |
Chen T, Koga K, Li X, Zhuo M. Spinal microglial motility is independent of neuronal activity and plasticity in adult mice. Mol Pain. 2010;6:19 pubmed 出版商 |
Steiner D, Khaner H, Cohen M, Even Ram S, Gil Y, Itsykson P, et al. Derivation, propagation and controlled differentiation of human embryonic stem cells in suspension. Nat Biotechnol. 2010;28:361-4 pubmed 出版商 |
Cazorla M, Jouvenceau A, Rose C, Guilloux J, Pilon C, Dranovsky A, et al. Cyclotraxin-B, the first highly potent and selective TrkB inhibitor, has anxiolytic properties in mice. PLoS ONE. 2010;5:e9777 pubmed 出版商 |
Greer P, Hanayama R, Bloodgood B, Mardinly A, Lipton D, Flavell S, et al. The Angelman Syndrome protein Ube3A regulates synapse development by ubiquitinating arc. Cell. 2010;140:704-16 pubmed 出版商 |
Taraballi F, Natalello A, Campione M, Villa O, Doglia S, Paleari A, et al. Glycine-spacers influence functional motifs exposure and self-assembling propensity of functionalized substrates tailored for neural stem cell cultures. Front Neuroeng. 2010;3:1 pubmed 出版商 |
Garavaglia A, Moiana A, Camnasio S, Bolognini D, Papait R, Rigamonti D, et al. Adaptation of NS cells growth and differentiation to high-throughput screening-compatible plates. BMC Neurosci. 2010;11:7 pubmed 出版商 |
Wu L, Fan Y, Li S, Li X, Zhou X. Huntingtin-associated protein-1 interacts with pro-brain-derived neurotrophic factor and mediates its transport and release. J Biol Chem. 2010;285:5614-23 pubmed 出版商 |
Hu B, Du Z, Zhang S. Differentiation of human oligodendrocytes from pluripotent stem cells. Nat Protoc. 2009;4:1614-22 pubmed 出版商 |
Imamura F, Greer C. Dendritic branching of olfactory bulb mitral and tufted cells: regulation by TrkB. PLoS ONE. 2009;4:e6729 pubmed 出版商 |
Hu B, Zhang S. Differentiation of spinal motor neurons from pluripotent human stem cells. Nat Protoc. 2009;4:1295-304 pubmed 出版商 |
Blurton Jones M, Kitazawa M, Martinez Coria H, Castello N, Muller F, Loring J, et al. Neural stem cells improve cognition via BDNF in a transgenic model of Alzheimer disease. Proc Natl Acad Sci U S A. 2009;106:13594-9 pubmed 出版商 |
Tomé M, Lindsay S, Riddell J, Barnett S. Identification of nonepithelial multipotent cells in the embryonic olfactory mucosa. Stem Cells. 2009;27:2196-208 pubmed 出版商 |
Hollis E, Jamshidi P, L xf6 w K, Blesch A, Tuszynski M. Induction of corticospinal regeneration by lentiviral trkB-induced Erk activation. Proc Natl Acad Sci U S A. 2009;106:7215-20 pubmed 出版商 |
Huang S, Zhao L, Sun Z, Li X, Geng Z, Zhang K, et al. Essential role of Hrs in endocytic recycling of full-length TrkB receptor but not its isoform TrkB.T1. J Biol Chem. 2009;284:15126-36 pubmed 出版商 |
Borgs L, Beukelaers P, Vandenbosch R, Nguyen L, Moonen G, Maquet P, et al. Period 2 regulates neural stem/progenitor cell proliferation in the adult hippocampus. BMC Neurosci. 2009;10:30 pubmed 出版商 |
Fiore R, Khudayberdiev S, Christensen M, Siegel G, Flavell S, Kim T, et al. Mef2-mediated transcription of the miR379-410 cluster regulates activity-dependent dendritogenesis by fine-tuning Pumilio2 protein levels. EMBO J. 2009;28:697-710 pubmed 出版商 |
Ebert A, Yu J, Rose F, Mattis V, Lorson C, Thomson J, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature. 2009;457:277-80 pubmed 出版商 |
Goffredo D, Conti L, Di Febo F, Biella G, Tosoni A, Vago G, et al. Setting the conditions for efficient, robust and reproducible generation of functionally active neurons from adult subventricular zone-derived neural stem cells. Cell Death Differ. 2008;15:1847-56 pubmed 出版商 |
Zhou X, Wu K, Liang B, Fu X, Luo Z. TrkB-mediated activation of geranylgeranyltransferase I promotes dendritic morphogenesis. Proc Natl Acad Sci U S A. 2008;105:17181-6 pubmed 出版商 |
Fletcher J, Morton C, Zwar R, Murray S, O Leary P, Hughes R. Design of a conformationally defined and proteolytically stable circular mimetic of brain-derived neurotrophic factor. J Biol Chem. 2008;283:33375-83 pubmed 出版商 |
Agterberg M, Versnel H, de Groot J, Smoorenburg G, Albers F, Klis S. Morphological changes in spiral ganglion cells after intracochlear application of brain-derived neurotrophic factor in deafened guinea pigs. Hear Res. 2008;244:25-34 pubmed 出版商 |
Kettunen P, Spencer Dene B, Furmanek T, Kvinnsland I, Dickson C, Thesleff I, et al. Fgfr2b mediated epithelial-mesenchymal interactions coordinate tooth morphogenesis and dental trigeminal axon patterning. Mech Dev. 2007;124:868-83 pubmed |
Qin H, Yu T, Qing T, Liu Y, Zhao Y, Cai J, et al. Regulation of apoptosis and differentiation by p53 in human embryonic stem cells. J Biol Chem. 2007;282:5842-52 pubmed |
Cass W, Peters L, Harned M, Seroogy K. Protection by GDNF and other trophic factors against the dopamine-depleting effects of neurotoxic doses of methamphetamine. Ann N Y Acad Sci. 2006;1074:272-81 pubmed |
Gama C, Tully S, Sotogaku N, Clark P, Rawat M, Vaidehi N, et al. Sulfation patterns of glycosaminoglycans encode molecular recognition and activity. Nat Chem Biol. 2006;2:467-73 pubmed |
Soen Y, Mori A, Palmer T, Brown P. Exploring the regulation of human neural precursor cell differentiation using arrays of signaling microenvironments. Mol Syst Biol. 2006;2:37 pubmed |
Pyle A, Lock L, Donovan P. Neurotrophins mediate human embryonic stem cell survival. Nat Biotechnol. 2006;24:344-50 pubmed |
Studer L, Tabar V, McKay R. Transplantation of expanded mesencephalic precursors leads to recovery in parkinsonian rats. Nat Neurosci. 1998;1:290-5 pubmed |
