产品简要
公司名称 :
赛默飞世尔
其他品牌 :
NeoMarkers, Lab Vision, Endogen, Pierce, BioSource International, Zymed Laboratories, Caltag, Molecular Probes, Research Genetics, Life Technologies, Applied Biosystems, GIBCO BRL, ABgene, Dynal, Affinity BioReagents, Nunc, Invitrogen, NatuTec, Oxoid, Richard-Allan Scientific, Arcturus, Perseptive Biosystems, Proxeon, eBioscience
产品类型 :
抗体
产品名称 :
磷酸化INSR(Tyr972)多克隆抗体
目录 :
44-800G
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
抗原修饰 :
磷酸化
反应物种 :
人类, 小鼠
应用 :
免疫印迹, 免疫细胞化学, 其他
更多信息或购买 :
赛默飞世尔 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 小鼠; 图 8b
Wang H, Lee K, Pei Z, Khan A, Bakshi K, Burns L. PTI-125 binds and reverses an altered conformation of filamin A to reduce Alzheimer's disease pathogenesis. Neurobiol Aging. 2017;55:99-114 pubmed 出版商
  • 免疫印迹; 人类; 图 6a
Cieniewicz A, Kirchner T, Hinke S, Nanjunda R, D AQUINO K, Boayke K, et al. Novel Monoclonal Antibody Is an Allosteric Insulin Receptor Antagonist That Induces Insulin Resistance. Diabetes. 2017;66:206-217 pubmed 出版商
  • 其他; 人类; 图 7
Cieniewicz A, Cooper P, MCGEHEE J, Lingham R, Kihm A. Novel method demonstrates differential ligand activation and phosphatase-mediated deactivation of insulin receptor tyrosine-specific phosphorylation. Cell Signal. 2016;28:1037-47 pubmed 出版商
You D, Chul Jung B, Villivalam S, Lim H, Kang S. JMJD8 is a Novel Molecular Nexus Between Adipocyte-Intrinsic Inflammation and Insulin Resistance. Diabetes. 2021;: pubmed 出版商
Ferrara P, Rong X, Maschek J, Verkerke A, Siripoksup P, Song H, et al. Lysophospholipid acylation modulates plasma membrane lipid organization and insulin sensitivity in skeletal muscle. J Clin Invest. 2021;131: pubmed 出版商
Nakazawa H, Ikeda K, Shinozaki S, Yasuhara S, Yu Y, Martyn J, et al. Coenzyme Q10 protects against burn-induced mitochondrial dysfunction and impaired insulin signaling in mouse skeletal muscle. FEBS Open Bio. 2019;9:348-363 pubmed 出版商
Kim J, Toda C, Ramírez C, Fernandez Hernando C, Diano S. Hypothalamic Ventromedial Lin28a Enhances Glucose Metabolism in Diet-Induced Obesity. Diabetes. 2017;66:2102-2111 pubmed 出版商
Mollica M, Mattace Raso G, Cavaliere G, Trinchese G, De Filippo C, Aceto S, et al. Butyrate Regulates Liver Mitochondrial Function, Efficiency, and Dynamics in Insulin-Resistant Obese Mice. Diabetes. 2017;66:1405-1418 pubmed 出版商
Nakazawa H, Yamada M, Tanaka T, Kramer J, Yu Y, Fischman A, et al. Role of protein farnesylation in burn-induced metabolic derangements and insulin resistance in mouse skeletal muscle. PLoS ONE. 2015;10:e0116633 pubmed 出版商
产品信息
产品类型 :
抗体
产品名称 :
磷酸化INSR(Tyr972)多克隆抗体
目录# :
44-800G
规格 :
100微升
价格 :
美国425.00
克隆性 :
多克隆
纯度 :
抗原亲和色谱
宿主 :
兔
反应物种 :
人类, 小鼠
应用 :
Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000
物种 :
人类, 小鼠
抗体亚型 :
IgG
储存 :
-20°C
描述 :
INSR is a receptor tyrosine kinase. Binding of insulin to the extracellular domain of INSR stimulates glucose uptake. INSR and IGF-1 receptors share major structural and functional similarity. The earliest cellular response to insulin stimulation is autophosphorylation of tyrosine in INSR. In humans, the INSR gene is located on chromosome 19. Defects in INSR are the cause of various insulin resistance syndromes and IGF-1R defects may also cause some forms of growth retardation.
免疫原 :
The antiserum was produced against a chemically synthesized phosphopeptide derived from the region of the human insulin receptor that contains tyrosine 972, as numbered according to Ebina, et al. (tyrosine 960 according to Ullrich, et al.). The sequence is conserved in mouse and rat.
格式 :
液体
应用w/稀释 :
Immunocytochemistry: 1:100-1:500, Western Blot: 1:1,000
别名 :
4932439J01Rik; CD 220; CD220; CD220 antigen; CD220 beta; CD221; D630014A15Rik; HHF 5; HHF5; IGF-I receptor; INSR; Insulin receptor; insulin receptor preproprotein; Insulin receptor subunit alpha; Insulin receptor subunit beta; IR; IR 1; IR beta; IR1; IR-1; IR-A; IR-B
更多信息或购买 :
赛默飞世尔 产品网页
公司信息
赛默飞世尔
上海浦东新金桥路27号7号楼
analyze.cn@thermofisher.com
http://www.thermo.com.cn
1084193588
公司总部: 美国